Therapeutically targeting ErbB3: A key node in ligand-induced activation of the ErbB receptor–PI3K axis B Schoeberl, EA Pace, JB Fitzgerald, BD Harms, L Xu, L Nie, B Linggi, ... Science signaling 2 (77), ra31-ra31, 2009 | 417 | 2009 |
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3 CF McDonagh, A Huhalov, BD Harms, S Adams, V Paragas, S Oyama, ... Molecular cancer therapeutics 11 (3), 582-593, 2012 | 344 | 2012 |
MM-141, an IGF-IR–and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors JB Fitzgerald, BW Johnson, J Baum, S Adams, S Iadevaia, J Tang, ... Molecular cancer therapeutics 13 (2), 410-425, 2014 | 119 | 2014 |
Enhanced targeting of the EGFR network with MM-151, an oligoclonal anti-EGFR antibody therapeutic JD Kearns, R Bukhalid, M Sevecka, G Tan, N Gerami-Moayed, SL Werner, ... Molecular Cancer Therapeutics 14 (7), 1625-1636, 2015 | 81 | 2015 |
A novel screening method to assess developability of antibody-like molecules N Kohli, N Jain, ML Geddie, M Razlog, L Xu, AA Lugovskoy MAbs 7 (4), 752-758, 2015 | 63 | 2015 |
Renewable dehydrogenase-based interfaces for bioelectronic applications BL Hassler, N Kohli, JG Zeikus, I Lee, RM Worden Langmuir 23 (13), 7127-7133, 2007 | 46 | 2007 |
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models WS Kamoun, DB Kirpotin, ZR Huang, SK Tipparaju, CO Noble, ME Hayes, ... Nature Biomedical Engineering 3 (4), 264-280, 2019 | 44 | 2019 |
Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity EM Tam, RB Fulton, JF Sampson, M Muda, A Camblin, J Richards, ... Science translational medicine 11 (512), eaax0720, 2019 | 42 | 2019 |
Rapid optimization and prototyping for therapeutic antibody-like molecules L Xu, N Kohli, R Rennard, Y Jiao, M Razlog, K Zhang, J Baum, B Johnson, ... MAbs 5 (2), 237-254, 2013 | 35 | 2013 |
Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle K Zhang, ML Geddie, N Kohli, T Kornaga, DB Kirpotin, Y Jiao, R Rennard, ... MAbs 7 (1), 42-52, 2015 | 33 | 2015 |
Optimizing properties of antireceptor antibodies using kinetic computational models and experiments BD Harms, JD Kearns, SV Su, N Kohli, UB Nielsen, B Schoeberl Methods in enzymology 502, 67-87, 2012 | 33 | 2012 |
Arrays of lipid bilayers and liposomes on patterned polyelectrolyte templates N Kohli, S Vaidya, RY Ofoli, RM Worden, I Lee Journal of colloid and interface science 301 (2), 461-469, 2006 | 33 | 2006 |
Nanostructured biosensor for measuring neuropathy target esterase activity N Kohli, D Srivastava, J Sun, RJ Richardson, I Lee, RM Worden Analytical chemistry 79 (14), 5196-5203, 2007 | 31 | 2007 |
Nanostructured crosslinkable micropatterns by amphiphilic dendrimer stamping N Kohli, PR Dvornic, SN Kaganove, RM Worden, I Lee Macromolecular rapid communications 25 (9), 935-941, 2004 | 31 | 2004 |
Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody–Drug Conjugates to Increase In Vivo Efficacy JF Ponte, L Lanieri, E Khera, R Laleau, O Ab, C Espelin, N Kohli, B Matin, ... Molecular cancer therapeutics 20 (1), 203-212, 2021 | 30 | 2021 |
Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting ML Geddie, N Kohli, DB Kirpotin, M Razlog, Y Jiao, T Kornaga, ... MAbs 9 (1), 58-67, 2017 | 29 | 2017 |
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM JB Casaletto, ML Geddie, AO Abu-Yousif, K Masson, A Fulgham, ... Proceedings of the National Academy of Sciences 116 (15), 7533-7542, 2019 | 28 | 2019 |
Bispecific anti-IGF-1R and anti-ErbB3 antibodies J Baum, B Johnson, AA Lugovskoy, LH Xu, N Kohli, JB Fitzgerald, ... US Patent 8,476,409, 2013 | 25 | 2013 |
Bispecific binding agents targeting igf-1r and erbb3 signalling and uses thereof B Schoeberl, U Nielsen, AJ Kudla, A Muruganandam, D Buckler, ... US Patent App. 13/443,660, 2012 | 24 | 2012 |
Direct transfer of preformed patterned bio‐nanocomposite films on polyelectrolyte multilayer templates N Kohli, RM Worden, I Lee Macromolecular bioscience 7 (6), 789-797, 2007 | 22 | 2007 |