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Alexander Koers
Alexander Koers
Imaging Sciences and Biomedical Engineering, Department of Chemistry/Biology, King's College
Dirección de correo verificada de kcl.ac.uk
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IgG4 subclass antibodies impair antitumor immunity in melanoma
P Karagiannis, AE Gilbert, DH Josephs, N Ali, T Dodev, L Saul, I Correa, ...
The Journal of clinical investigation 123 (4), 1457-1474, 2013
2212013
Efficient bifunctional gallium-68 chelators for positron emission tomography: tris (hydroxypyridinone) ligands
DJ Berry, Y Ma, JR Ballinger, R Tavaré, A Koers, K Sunassee, T Zhou, ...
Chemical communications 47 (25), 7068-7070, 2011
1812011
FS118, a bispecific antibody targeting LAG-3 and PD-L1, enhances T-cell activation resulting in potent antitumor activity
M Kraman, M Faroudi, NL Allen, K Kmiecik, D Gliddon, C Seal, A Koers, ...
Clinical cancer research 26 (13), 3333-3344, 2020
942020
Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies
AE Gilbert, P Karagiannis, T Dodev, A Koers, K Lacy, DH Josephs, ...
PloS one 6 (4), e19330, 2011
902011
Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein
F Kampmeier, J Niesen, A Koers, M Ribbert, A Brecht, R Fischer, ...
European journal of nuclear medicine and molecular imaging 37, 1926-1934, 2010
742010
Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFα/MCP-1 signaling
DH Josephs, HJ Bax, T Dodev, M Georgouli, M Nakamura, G Pellizzari, ...
Cancer research 77 (5), 1127-1141, 2017
722017
In vivo SPECT reporter gene imaging of regulatory T cells
E Sharif-Paghaleh, K Sunassee, R Tavaré, K Ratnasothy, A Koers, N Ali, ...
PloS one 6 (10), e25857, 2011
632011
Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application
SN Karagiannis, DH Josephs, P Karagiannis, AE Gilbert, L Saul, ...
Cancer Immunology, Immunotherapy 61, 1547-1564, 2012
592012
Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI‐mediated basophil activation by a tumour‐specific IgE antibody to evaluate …
SM Rudman, DH Josephs, H Cambrook, P Karagiannis, AE Gilbert, ...
Clinical & Experimental Allergy 41 (10), 1400-1413, 2011
482011
FS222, a CD137/PD-L1 tetravalent bispecific antibody, exhibits low toxicity and antitumor activity in colorectal cancer models
MA Lakins, A Koers, R Giambalvo, J Munoz-Olaya, R Hughes, ...
Clinical Cancer Research 26 (15), 4154-4167, 2020
462020
p53 loss in MYC-driven neuroblastoma leads to metabolic adaptations supporting radioresistance
O Yogev, K Barker, A Sikka, GS Almeida, A Hallsworth, LM Smith, Y Jamin, ...
Cancer research 76 (10), 3025-3035, 2016
362016
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma
G Carreno, JKR Boult, J Apps, JM Gonzalez-Meljem, S Haston, R Guiho, ...
Endocrine-related cancer 26 (3), 355-366, 2019
252019
MRI imaging of the hemodynamic vasculature of neuroblastoma predicts response to antiangiogenic treatment
K Zormpas-Petridis, NP Jerome, MD Blackledge, F Carceller, E Poon, ...
Cancer research 79 (11), 2978-2991, 2019
212019
Noninvasive MRI Native T1 Mapping Detects Response to MYCN-targeted Therapies in the Th-MYCN Model of Neuroblastoma
K Zormpas-Petridis, E Poon, M Clarke, NP Jerome, JKR Boult, ...
Cancer research 80 (16), 3424-3435, 2020
202020
Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma
JKR Boult, JR Apps, A Hölsken, JC Hutchinson, G Carreno, LS Danielson, ...
Brain pathology 28 (4), 475-483, 2018
192018
Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces CD8+ T-cell activation and modulates the tumor microenvironment to promote antitumor immune …
M Kraman, N Fosh, K Kmiecik, K Everett, C Zimarino, M Faroudi, M Wydro, ...
Cancer research 78 (13_Supplement), 2719-2719, 2018
162018
Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
J Chauhan, M Grandits, LCGF Palhares, S Mele, M Nakamura, ...
Nature Communications 14 (1), 2192, 2023
62023
Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces T-cell activation with the potential to drive potent anti-tumour immune responses
M Kraman, N Fosh, K Kmiecik, K Everett, C Zimarino, M Faroudi, M Wydro, ...
J. Immunother. Cancer 5, P348, 2017
62017
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration
JG Kettle, SK Bagal, D Barratt, MS Bodnarchuk, S Boyd, E Braybrooke, ...
Journal of Medicinal Chemistry 66 (13), 9147-9160, 2023
32023
Metal ion chelation as a basis for pretargeting
PJ Blower, MS Cooper, S Nawaz, A O'Neill, A Koers, K Sunassee, ...
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 39, S262-S262, 2012
32012
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Artículos 1–20