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Amrendra Kumar Ajay
Amrendra Kumar Ajay
Faculty member, Harvard Medical School, Brigham and Women's Hospital, Boston
Dirección de correo verificada de bwh.harvard.edu
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MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
G Murugaiyan, AP Da Cunha, AK Ajay, N Joller, LP Garo, S Kumaradevan, ...
The Journal of clinical investigation 125 (3), 1069-1080, 2015
2442015
A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer
A Kulkarni, V Chandrasekar, SK Natarajan, A Ramesh, P Pandey, ...
Nature biomedical engineering 2 (8), 589-599, 2018
1632018
IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease
JH Baek, R Zeng, J Weinmann-Menke, MT Valerius, Y Wada, AK Ajay, ...
The Journal of clinical investigation 125 (8), 3198-3214, 2015
1372015
A quantitative approach to screen for nephrotoxic compounds in vitro
M Adler, S Ramm, M Hafner, JL Muhlich, EM Gottwald, E Weber, A Jaklic, ...
Journal of the American Society of Nephrology 27 (4), 1015-1028, 2016
1282016
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
Y Mori, AK Ajay, JH Chang, S Mou, H Zhao, S Kishi, J Li, CR Brooks, ...
Cell metabolism 33 (5), 1042-1061. e7, 2021
1222021
p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: a novel target of p53 in apoptosis
S Singh, AK Upadhyay, AK Ajay, MK Bhat
FEBS letters 581 (2), 289-295, 2007
1072007
Diet‐induced obesity increases melanoma progression: involvement of Cav‐1 and FASN
V Pandey, MV Vijayakumar, AK Ajay, P Malvi, MK Bhat
International journal of cancer 130 (3), 497-508, 2012
932012
MicroRNA-146a limits tumorigenic inflammation in colorectal cancer
LP Garo, AK Ajay, M Fujiwara, G Gabriely, R Raheja, C Kuhn, B Kenyon, ...
Nature communications 12 (1), 2419, 2021
802021
RNA sequencing identifies novel translational biomarkers of kidney fibrosis
FL Craciun, V Bijol, AK Ajay, P Rao, RK Kumar, J Hutchinson, O Hofmann, ...
Journal of the American society of nephrology 27 (6), 1702-1713, 2016
702016
A bioinformatics approach identifies signal transducer and activator of transcription-3 and checkpoint kinase 1 as upstream regulators of kidney injury molecule-1 after kidney …
AK Ajay, TM Kim, V Ramirez-Gonzalez, PJ Park, DA Frank, VS Vaidya
Journal of the American Society of Nephrology 25 (1), 105-118, 2014
672014
Fibrinogen β–derived Bβ15-42 peptide protects against kidney ischemia/ reperfusion injury
A Krishnamoorthy, AK Ajay, D Hoffmann, TM Kim, V Ramirez, ...
Blood, The Journal of the American Society of Hematology 118 (7), 1934-1942, 2011
642011
Synthesis, characterization, plasmid cleavage and cytotoxicity of cancer cells by a copper (II) complex of anthracenyl-terpyridine
A Kumar, JP Chinta, AK Ajay, MK Bhat, CP Rao
Dalton Transactions 40 (41), 10865-10872, 2011
622011
Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation
C Gerarduzzi, RK Kumar, P Trivedi, AK Ajay, A Iyer, S Boswell, ...
JCI insight 2 (8), 2017
572017
Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis
FL Craciun, AK Ajay, D Hoffmann, J Saikumar, SL Fabian, V Bijol, ...
American Journal of Physiology-Renal Physiology 307 (4), F471-F484, 2014
572014
Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression
AK Ajay, AK Upadhyay, S Singh, MV Vijayakumar, R Kumari, V Pandey, ...
Molecular cancer 9, 1-15, 2010
562010
Methyl-β-cyclodextrin enhances the susceptibility of human breast cancer cells to carboplatin and 5-fluorouracil: Involvement of Akt, NF-κB and Bcl-2
AK Upadhyay, S Singh, RR Chhipa, MV Vijayakumar, AK Ajay, MK Bhat
Toxicology and applied pharmacology 216 (2), 177-185, 2006
532006
Smad7 controls immunoregulatory PDL2/1-PD1 signaling in intestinal inflammation and autoimmunity
LP Garo, AK Ajay, M Fujiwara, V Beynon, C Kuhn, G Gabriely, ...
Cell reports 28 (13), 3353-3366. e5, 2019
472019
Cell cycle regulatory protein 5 (Cdk5) is a novel downstream target of ERK in carboplatin induced death of breast cancer cells (supplementary data)
AK Upadhyay, AK Ajay, S Singh, MK Bhat
Current cancer drug targets 8 (8), 741-752, 2008
402008
Genetic reduction of cilium length by targeting intraflagellar transport 88 protein impedes kidney and liver cyst formation in mouse models of autosomal polycystic kidney disease
L Shao, W El-Jouni, F Kong, J Ramesh, RS Kumar, X Shen, J Ren, ...
Kidney international 98 (5), 1225-1241, 2020
382020
IL-34–Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice
Y Wada, HM Gonzalez-Sanchez, J Weinmann-Menke, Y Iwata, AK Ajay, ...
Journal of the American Society of Nephrology 30 (2), 244-259, 2019
382019
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Artículos 1–20