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Fadi Jacob
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Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure
X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, ...
Cell 165 (5), 1238-1254, 2016
19462016
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
6892016
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity
F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...
Cell 180 (1), 188-204. e22, 2020
6512020
Temporal control of mammalian cortical neurogenesis by m6A methylation
KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, ...
Cell 171 (4), 877-889. e17, 2017
6452017
Generation of human brain region–specific organoids using a miniaturized spinning bioreactor
X Qian, F Jacob, MM Song, HN Nguyen, H Song, G Ming
Nature protocols 13 (3), 565, 2018
3942018
Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
F Jacob, SR Pather, WK Huang, F Zhang, SZH Wong, H Zhou, B Cubitt, ...
Cell stem cell 27 (6), 937-950. e9, 2020
3662020
Sliced human cortical organoids for modeling distinct cortical layer formation
X Qian, Y Su, CD Adam, AU Deutschmann, SR Pather, EM Goldberg, ...
Cell stem cell 26 (5), 766-781. e9, 2020
3172020
Using brain organoids to understand Zika virus-induced microcephaly
X Qian, HN Nguyen, F Jacob, H Song, G Ming
Development 144 (6), 952-957, 2017
2312017
Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins
KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho, NS Kim, C Habela, ...
Cell stem cell 21 (3), 349-358. e6, 2017
1942017
Defining the cellular lineage hierarchy in the interfollicular epidermis of adult skin
A Sada, F Jacob, E Leung, S Wang, BS White, D Shalloway, T Tumbar
Nature cell biology 18 (6), 619-631, 2016
1872016
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes
M Song, X Yang, X Ren, L Maliskova, B Li, IR Jones, C Wang, F Jacob, ...
Nature genetics 51 (8), 1252-1262, 2019
1642019
DISC1 regulates neurogenesis via modulating kinetochore attachment of Ndel1/Nde1 during mitosis
F Ye, E Kang, C Yu, X Qian, F Jacob, C Yu, M Mao, RYC Poon, J Kim, ...
Neuron 96 (5), 1041-1054. e5, 2017
1532017
Molecular landscapes of human hippocampal immature neurons across lifespan
Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond, Y Sun, F Jacob, ...
Nature 607 (7919), 527-533, 2022
1352022
Generation and biobanking of patient-derived glioblastoma organoids and their application in CAR T cell testing
F Jacob, G Ming, H Song
Nature protocols 15 (12), 4000-4033, 2020
1052020
Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma
I Makhlin, RD Salinas, D Zhang, F Jacob, G Ming, H Song, D Saxena, ...
CNS oncology 8 (3), CNS43, 2019
452019
Structural and functional integration of human forebrain organoids with the injured adult rat visual system
D Jgamadze, JT Lim, Z Zhang, PM Harary, J Germi, K Mensah-Brown, ...
Cell Stem Cell 30 (2), 137-152. e7, 2023
432023
Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease
F Jacob, JG Schnoll, H Song, G Ming
Current topics in developmental biology 142, 477-530, 2021
182021
Modeling neurological disease using human stem cell-derived microglia-like cells transplanted into rodent brains
F Jacob, ML Bennett
Lab animal 49 (2), 49-51, 2020
42020
Volumetric analysis of spheno-orbital meningiomas: prognostic correlation and a compartmentalized approach
YM Zohdy, F Jacob, M Agam, A Alawieh, D Bray, JMR Barbero, SA Argaw, ...
Neurosurgery 94 (4), 736-744, 2024
22024
A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment
X Lin, W Wang, M Yang, N Damseh, MML de Sousa, F Jacob, A Lång, ...
Genome Biology 24 (1), 216, 2023
2*2023
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