Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13481* | 2021 |
TFEB links autophagy to lysosomal biogenesis C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ... science 332 (6036), 1429-1433, 2011 | 3140 | 2011 |
A gene network regulating lysosomal biogenesis and function M Sardiello, M Palmieri, A Di Ronza, DL Medina, M Valenza, ... Science 325 (5939), 473-477, 2009 | 2536 | 2009 |
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB C Settembre, R Zoncu, DL Medina, F Vetrini, S Erdin, SU Erdin, T Huynh, ... The EMBO journal 31 (5), 1095-1108, 2012 | 1974 | 2012 |
Signals from the lysosome: a control centre for cellular clearance and energy metabolism C Settembre, A Fraldi, DL Medina, A Ballabio Nature reviews Molecular cell biology 14 (5), 283-296, 2013 | 1765 | 2013 |
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ... Nature cell biology 17 (3), 288-299, 2015 | 1294 | 2015 |
Transcriptional activation of lysosomal exocytosis promotes cellular clearance DL Medina, A Fraldi, V Bouche, F Annunziata, G Mansueto, ... Developmental cell 21 (3), 421-430, 2011 | 794 | 2011 |
Mechanism of TrkB-mediated hippocampal long-term potentiation L Minichiello, AM Calella, DL Medina, T Bonhoeffer, R Klein, M Korte Neuron 36 (1), 121-137, 2002 | 616 | 2002 |
A block of autophagy in lysosomal storage disorders C Settembre, A Fraldi, L Jahreiss, C Spampanato, C Venturi, D Medina, ... Human molecular genetics 17 (1), 119-129, 2008 | 604 | 2008 |
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition A Luciani, VR Villella, S Esposito, N Brunetti-Pierri, D Medina, ... Nature cell biology 12 (9), 863-875, 2010 | 537 | 2010 |
mTOR-dependent phosphorylation controls TFEB nuclear export G Napolitano, A Esposito, H Choi, M Matarese, V Benedetti, C Di Malta, ... Nature communications 9 (1), 3312, 2018 | 349 | 2018 |
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders A Fraldi, F Annunziata, A Lombardi, HJ Kaiser, DL Medina, ... The EMBO journal 29 (21), 3607-3620, 2010 | 248 | 2010 |
FGF signalling regulates bone growth through autophagy L Cinque, A Forrester, R Bartolomeo, M Svelto, R Venditti, S Montefusco, ... Nature 528 (7581), 272-275, 2015 | 199 | 2015 |
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition JX Song, YR Sun, I Peluso, Y Zeng, X Yu, JH Lu, Z Xu, MZ Wang, LF Liu, ... Autophagy 12 (8), 1372-1389, 2016 | 180 | 2016 |
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis SE Mole, G Anderson, HA Band, SF Berkovic, JD Cooper, SMK Holthaus, ... The Lancet Neurology 18 (1), 107-116, 2019 | 174 | 2019 |
Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL MG De Leo, L Staiano, M Vicinanza, A Luciani, A Carissimo, M Mutarelli, ... Nature cell biology 18 (8), 839-850, 2016 | 169 | 2016 |
Brain disorders due to lysosomal dysfunction A Fraldi, AD Klein, DL Medina, C Settembre Annual review of neuroscience 39 (1), 277-295, 2016 | 167 | 2016 |
The rapidly evolving view of lysosomal storage diseases G Parenti, DL Medina, A Ballabio EMBO molecular medicine 13 (2), e12836, 2021 | 161 | 2021 |
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway A Scotto Rosato, S Montefusco, C Soldati, S Di Paola, A Capuozzo, ... Nature communications 10 (1), 5630, 2019 | 154 | 2019 |
TRPML1: The Ca (2+) retaker of the lysosome S Di Paola, A Scotto-Rosato, DL Medina Cell calcium 69, 112-121, 2018 | 151 | 2018 |