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Diego L. Medina
Diego L. Medina
Head, High Content Screening Facility, Telethon Institute of Genetics and Medicine (TIGEM)
Dirección de correo verificada de tigem.it
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Año
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13481*2021
TFEB links autophagy to lysosomal biogenesis
C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ...
science 332 (6036), 1429-1433, 2011
31402011
A gene network regulating lysosomal biogenesis and function
M Sardiello, M Palmieri, A Di Ronza, DL Medina, M Valenza, ...
Science 325 (5939), 473-477, 2009
25362009
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
C Settembre, R Zoncu, DL Medina, F Vetrini, S Erdin, SU Erdin, T Huynh, ...
The EMBO journal 31 (5), 1095-1108, 2012
19742012
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
C Settembre, A Fraldi, DL Medina, A Ballabio
Nature reviews Molecular cell biology 14 (5), 283-296, 2013
17652013
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ...
Nature cell biology 17 (3), 288-299, 2015
12942015
Transcriptional activation of lysosomal exocytosis promotes cellular clearance
DL Medina, A Fraldi, V Bouche, F Annunziata, G Mansueto, ...
Developmental cell 21 (3), 421-430, 2011
7942011
Mechanism of TrkB-mediated hippocampal long-term potentiation
L Minichiello, AM Calella, DL Medina, T Bonhoeffer, R Klein, M Korte
Neuron 36 (1), 121-137, 2002
6162002
A block of autophagy in lysosomal storage disorders
C Settembre, A Fraldi, L Jahreiss, C Spampanato, C Venturi, D Medina, ...
Human molecular genetics 17 (1), 119-129, 2008
6042008
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
A Luciani, VR Villella, S Esposito, N Brunetti-Pierri, D Medina, ...
Nature cell biology 12 (9), 863-875, 2010
5372010
mTOR-dependent phosphorylation controls TFEB nuclear export
G Napolitano, A Esposito, H Choi, M Matarese, V Benedetti, C Di Malta, ...
Nature communications 9 (1), 3312, 2018
3492018
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders
A Fraldi, F Annunziata, A Lombardi, HJ Kaiser, DL Medina, ...
The EMBO journal 29 (21), 3607-3620, 2010
2482010
FGF signalling regulates bone growth through autophagy
L Cinque, A Forrester, R Bartolomeo, M Svelto, R Venditti, S Montefusco, ...
Nature 528 (7581), 272-275, 2015
1992015
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition
JX Song, YR Sun, I Peluso, Y Zeng, X Yu, JH Lu, Z Xu, MZ Wang, LF Liu, ...
Autophagy 12 (8), 1372-1389, 2016
1802016
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis
SE Mole, G Anderson, HA Band, SF Berkovic, JD Cooper, SMK Holthaus, ...
The Lancet Neurology 18 (1), 107-116, 2019
1742019
Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL
MG De Leo, L Staiano, M Vicinanza, A Luciani, A Carissimo, M Mutarelli, ...
Nature cell biology 18 (8), 839-850, 2016
1692016
Brain disorders due to lysosomal dysfunction
A Fraldi, AD Klein, DL Medina, C Settembre
Annual review of neuroscience 39 (1), 277-295, 2016
1672016
The rapidly evolving view of lysosomal storage diseases
G Parenti, DL Medina, A Ballabio
EMBO molecular medicine 13 (2), e12836, 2021
1612021
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway
A Scotto Rosato, S Montefusco, C Soldati, S Di Paola, A Capuozzo, ...
Nature communications 10 (1), 5630, 2019
1542019
TRPML1: The Ca (2+) retaker of the lysosome
S Di Paola, A Scotto-Rosato, DL Medina
Cell calcium 69, 112-121, 2018
1512018
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20