| High interstitial fluid pressure—an obstacle in cancer therapy CH Heldin, K Rubin, K Pietras, A Östman Nature Reviews Cancer 4 (10), 806-813, 2004 | 2392 | 2004 |
| Protein detection using proximity-dependent DNA ligation assays S Fredriksson, M Gullberg, J Jarvius, C Olsson, K Pietras, ... Nature biotechnology 20 (5), 473-477, 2002 | 1678 | 2002 |
| Tertiary lymphoid structures improve immunotherapy and survival in melanoma R Cabrita, M Lauss, A Sanna, M Donia, M Skaarup Larsen, S Mitra, ... Nature 577 (7791), 561-565, 2020 | 1496 | 2020 |
| Hallmarks of cancer: interactions with the tumor stroma K Pietras, A Östman Experimental cell research 316 (8), 1324-1331, 2010 | 1491 | 2010 |
| A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition T Vincent, EPA Neve, JR Johnson, A Kukalev, F Rojo, J Albanell, ... Nature cell biology 11 (8), 943-950, 2009 | 782 | 2009 |
| PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor E Bergsten, M Uutela, X Li, K Pietras, A Östman, CH Heldin, K Alitalo, ... Nature cell biology 3 (5), 512-516, 2001 | 779 | 2001 |
| Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing M Bartoschek, N Oskolkov, M Bocci, J Lövrot, C Larsson, M Sommarin, ... Nature communications 9 (1), 5150, 2018 | 589 | 2018 |
| Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors K Pietras, A Ostman, M Sjöquist, E Buchdunger, RK Reed, CH Heldin, ... Cancer research 61 (7), 2929-2934, 2001 | 578 | 2001 |
| PDGF receptors as cancer drug targets K Pietras, T Sjöblom, K Rubin, CH Heldin, A Östman Cancer cell 3 (5), 439-443, 2003 | 575 | 2003 |
| Vascular endothelial growth factor B controls endothelial fatty acid uptake CE Hagberg, A Falkevall, X Wang, E Larsson, J Huusko, I Nilsson, ... Nature 464 (7290), 917-921, 2010 | 564 | 2010 |
| A multitargeted, metronomic, and maximum-tolerated dose “chemo-switch” regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer K Pietras, D Hanahan Journal of Clinical Oncology 23 (5), 939-952, 2005 | 563 | 2005 |
| Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy K Pietras, K Rubin, T Sjöblom, E Buchdunger, M Sjöquist, CH Heldin, ... Cancer research 62 (19), 5476-5484, 2002 | 558 | 2002 |
| Consensus guidelines for the use and interpretation of angiogenesis assays P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov, AC Aplin, R Auerbach, ... Angiogenesis 21, 425-532, 2018 | 554 | 2018 |
| Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke EJ Su, L Fredriksson, M Geyer, E Folestad, J Cale, J Andrae, Y Gao, ... Nature medicine 14 (7), 731-737, 2008 | 516 | 2008 |
| Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting K Pietras, J Pahler, G Bergers, D Hanahan PLoS medicine 5 (1), e19, 2008 | 512 | 2008 |
| The dermatofibrosarcoma protuberans-associated collagen type Iα1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to … A Shimizu, KP O’Brien, T Sjöblom, K Pietras, E Buchdunger, VP Collins, ... Cancer research 59 (15), 3719-3723, 1999 | 348 | 1999 |
| Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression M Franco, P Roswall, E Cortez, D Hanahan, K Pietras Blood, The Journal of the American Society of Hematology 118 (10), 2906-2917, 2011 | 332 | 2011 |
| Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis T Sjöblom, A Shimizu, KP O’Brien, K Pietras, P Dal Cin, E Buchdunger, ... Cancer Research 61 (15), 5778-5783, 2001 | 322 | 2001 |
| Angiogenesis stimulated by PDGF‐CC, a novel member in the PDGF family, involves activation of PDGFR‐aa and‐ap receptors R Cao, E Bråkenhielm, X Li, K Pietras, J Widenfalk, A Östman, U Eriksson, ... The FASEB Journal 16 (12), 1575-1583, 2002 | 307 | 2002 |
| Fibroblasts as architects of cancer pathogenesis T Marsh, K Pietras, SS McAllister Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (7 …, 2013 | 304 | 2013 |
