| Contribution of antibody hydrodynamic size to vitreal clearance revealed through rabbit studies using a species-matched fab W Shatz, PE Hass, M Mathieu, HS Kim, K Leach, M Zhou, Y Crawford, ... Molecular Pharmaceutics 13 (9), 2996-3003, 2016 | 72 | 2016 |
| Development and application of a physiologically based pharmacokinetic model for triadimefon and its metabolite triadimenol in rats and humans SR Crowell, WM Henderson, JF Kenneke, JW Fisher Toxicology letters 205 (2), 154-162, 2011 | 58 | 2011 |
| In vitro metabolism of benzo [a] pyrene and dibenzo [def, p] chrysene in rodent and human hepatic microsomes SR Crowell, S Hanson-Drury, DE Williams, RA Corley Toxicology letters 228 (1), 48-55, 2014 | 51 | 2014 |
| Mechanistic investigation of the noncytochrome P450-mediated metabolism of triadimefon to triadimenol in hepatic microsomes JF Kenneke, CS Mazur, SE Ritger, TJ Sack Chemical research in toxicology 21 (10), 1997-2004, 2008 | 49 | 2008 |
| Influence of charge, hydrophobicity, and size on vitreous pharmacokinetics of large molecules SR Crowell, K Wang, A Famili, W Shatz, KM Loyet, V Chang, Y Liu, ... Translational Vision Science & Technology 8 (6), 1-1, 2019 | 44 | 2019 |
| Preliminary physiologically based pharmacokinetic models for benzo [a] pyrene and dibenzo [def, p] chrysene in rodents SR Crowell, SG Amin, KA Anderson, G Krishnegowda, AK Sharma, ... Toxicology and applied pharmacology 257 (3), 365-376, 2011 | 43 | 2011 |
| Translational research to develop a human PBPK models tool kit—volatile organic compounds (VOCs) MM Mumtaz, M Ray, SR Crowell, D Keys, J Fisher, P Ruiz Journal of Toxicology and Environmental Health, Part A 75 (1), 6-24, 2012 | 33 | 2012 |
| Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye W Shatz, PE Hass, N Peer, MT Paluch, C Blanchette, G Han, W Sandoval, ... PLoS One 14 (6), e0218613, 2019 | 27 | 2019 |
| Impact of pregnancy on the pharmacokinetics of dibenzo [def, p] chrysene in mice SR Crowell, AK Sharma, S Amin, JJ Soelberg, NC Sadler, AT Wright, ... toxicological sciences 135 (1), 48-62, 2013 | 27 | 2013 |
| Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ WJ Meilandt, JA Maloney, J Imperio, G Lalehzadeh, T Earr, S Crowell, ... Alzheimer's research & therapy 11, 1-14, 2019 | 26 | 2019 |
| Human in Vivo Pharmacokinetics of [14C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing E Madeen, RA Corley, S Crowell, K Turteltaub, T Ognibene, M Malfatti, ... Chemical research in toxicology 28 (1), 126-134, 2015 | 24 | 2015 |
| Increased in vivo effector function of human IgG4 isotype antibodies through afucosylation Q Gong, M Hazen, B Marshall, SR Crowell, Q Ou, AW Wong, W Phung, ... MAbs 8 (6), 1098-1106, 2016 | 22 | 2016 |
| A preliminary regional PBPK model of lung metabolism for improving species dependent descriptions of 1, 3-butadiene and its metabolites J Campbell, C Van Landingham, S Crowell, R Gentry, D Kaden, ... Chemico-biological interactions 238, 102-110, 2015 | 21 | 2015 |
| In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes JN Smith, D Mehinagic, S Nag, SR Crowell, RA Corley Toxicology letters 269, 23-32, 2017 | 20 | 2017 |
| Translational approaches for brain delivery of biologics via cerebrospinal fluid SS Sadekar, M Bowen, H Cai, S Jamalian, H Rafidi, W Shatz‐Binder, ... Clinical Pharmacology & Therapeutics 111 (4), 826-834, 2022 | 19 | 2022 |
| Physiologically based pharmacokinetic modeling of ethyl acetate and ethanol in rodents and humans SR Crowell, JN Smith, JA Creim, W Faber, JG Teeguarden Regulatory Toxicology and Pharmacology 73 (1), 452-462, 2015 | 17 | 2015 |
| Hyaluronic acid–antibody fragment bioconjugates for extended ocular pharmacokinetics A Famili, SR Crowell, KM Loyet, D Mandikian, CA Boswell, D Cain, ... Bioconjugate Chemistry 30 (11), 2782-2789, 2019 | 15 | 2019 |
| Predicting lung dosimetry of inhaled particleborne benzo [a] pyrene using physiologically based pharmacokinetic modeling J Campbell, A Franzen, C Van Landingham, M Lumpkin, S Crowell, ... Inhalation Toxicology 28 (11), 520-535, 2016 | 10 | 2016 |
| Gender and species differences in triadimefon metabolism by rodent hepatic microsomes SR Crowell, WM Henderson, JW Fisher, JF Kenneke Toxicology letters 193 (1), 101-107, 2010 | 8 | 2010 |
| Translating dosimetry of Dibenzo [def, p] chrysene (DBC) and metabolites across dose and species using physiologically based pharmacokinetic (PBPK) modeling P Pande, EP Madeen, DE Williams, SR Crowell, TJ Ognibene, ... Toxicology and applied pharmacology 438, 115830, 2022 | 6 | 2022 |
David WilliamsProfessor of Environmental and Molecular Toxicology, Oregon State UniversityDirección de correo verificada de oregonstate.edu
