The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: In vitro and in vivo … C Carrasco-Pozo, KN Tan, M Reyes-Farias, N De La Jara, ST Ngo, ... Redox Biology 9, 229-243, 2016 | 98 | 2016 |
Potential role of skeletal muscle glucose metabolism on the regulation of insulin secretion ML Mizgier, M Casas, A Contreras‐Ferrat, P Llanos, JE Galgani Obesity Reviews 15 (7), 587-597, 2014 | 97 | 2014 |
Reduction in the desaturation capacity of the liver in mice subjected to high fat diet: Relation to LCPUFA depletion in liver and extrahepatic tissues R Valenzuela, C Barrera, A Espinosa, P Llanos, P Orellana, LA Videla Prostaglandins, Leukotrienes and Essential Fatty Acids 98, 7-14, 2015 | 94 | 2015 |
Glucose-Dependent Insulin Secretion in Pancreatic β-Cell Islets from Male Rats Requires Ca2+ Release via ROS-Stimulated Ryanodine Receptors P Llanos, A Contreras-Ferrat, G Barrientos, M Valencia, D Mears, ... PLoS One 10 (6), e0129238, 2015 | 79 | 2015 |
Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation A Contreras-Ferrat, P Llanos, C Vásquez, A Espinosa, ... Journal of cell science 127 (9), 1911-1923, 2014 | 71 | 2014 |
Isolation and purification of human placental plasma membranes from normal and pre-eclamptic pregnancies. A comparative study V Jimenez, M Henriquez, P Llanos, G Riquelme Placenta 25 (5), 422-437, 2004 | 62 | 2004 |
NOX2 inhibition impairs early muscle gene expression induced by a single exercise bout C Henríquez-Olguín, A Díaz-Vegas, Y Utreras-Mendoza, C Campos, ... Frontiers in physiology 7, 282, 2016 | 61 | 2016 |
Mitochondrial calcium increase induced by RyR1 and IP3R channel activation after membrane depolarization regulates skeletal muscle metabolism AR Díaz-Vegas, A Cordova, D Valladares, P Llanos, C Hidalgo, ... Frontiers in physiology 9, 791, 2018 | 57 | 2018 |
Lactate administration activates the ERK 1/2, mTORC 1, and AMPK pathways differentially according to skeletal muscle type in mouse H Cerda‐Kohler, C Henríquez‐Olguín, M Casas, TE Jensen, P Llanos, ... Physiological reports 6 (18), e13800, 2018 | 55 | 2018 |
Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells S Wehinger, R Ortiz, MI Díaz, A Aguirre, M Valenzuela, P Llanos, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (5), 693-708, 2015 | 52 | 2015 |
Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet A Espinosa, C Campos, A Díaz-Vegas, JE Galgani, N Juretic, ... International journal of molecular sciences 14 (8), 15740-15754, 2013 | 52 | 2013 |
The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice P Llanos, A Contreras-Ferrat, T Georgiev, C Osorio-Fuentealba, ... American Journal of Physiology-Endocrinology and Metabolism 308 (4), E294-E305, 2015 | 45 | 2015 |
Annexin 6 modulates the maxi-chloride channel of the apical membrane of syncytiotrophoblast isolated from human placenta G Riquelme, P Llanos, E Tischner, J Neil, B Campos Journal of Biological Chemistry 279 (48), 50601-50608, 2004 | 44 | 2004 |
Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet R Valenzuela, A Espinosa, P Llanos, MC Hernandez-Rodas, C Barrera, ... Food & function 7 (1), 140-150, 2016 | 43 | 2016 |
High-fat-diet-induced obesity produces spontaneous ventricular arrhythmias and increases the activity of ryanodine receptors in mice G Sánchez, F Araneda, JP Peña, JP Finkelstein, JA Riquelme, ... International journal of molecular sciences 19 (2), 533, 2018 | 35 | 2018 |
Membrane cholesterol in skeletal muscle: a novel player in excitation-contraction coupling and insulin resistance G Barrientos, P Sánchez-Aguilera, E Jaimovich, C Hidalgo, P Llanos Journal of diabetes research 2017, 2017 | 31 | 2017 |
High extracellular ATP levels released through pannexin-1 channels mediate inflammation and insulin resistance in skeletal muscle fibres of diet-induced obese mice G Jorquera, R Meneses-Valdés, G Rosales-Soto, D Valladares-Ide, ... Diabetologia 64, 1389-1401, 2021 | 30 | 2021 |
Role of ABCA1 on membrane cholesterol content, insulin-dependent Akt phosphorylation and glucose uptake in adult skeletal muscle fibers from mice P Sánchez-Aguilera, A Diaz-Vegas, C Campos, O Quinteros-Waltemath, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 29 | 2018 |
Prolonged activation of the Htr2b serotonin receptor impairs glucose stimulated insulin secretion and mitochondrial function in MIN6 cells LR Cataldo, ML Mizgier, R Bravo Sagua, F Jana, C Cárdenas, P Llanos, ... PLoS One 12 (1), e0170213, 2017 | 29 | 2017 |
NLRP3 inflammasome: Potential role in obesity related low-grade inflammation and insulin resistance in skeletal muscle G Jorquera, J Russell, M Monsalves-Álvarez, G Cruz, D Valladares-Ide, ... International journal of molecular sciences 22 (6), 3254, 2021 | 28 | 2021 |