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Houston Cole
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Near-infrared absorbing Ru (II) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma
LM Lifshits, JA Roque III, P Konda, S Monro, HD Cole, D von Dohlen, ...
Chemical Science 11 (43), 11740-11762, 2020
772020
Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy
JA Roque, PC Barrett, HD Cole, LM Lifshits, G Shi, S Monro, ...
Chemical science 11 (36), 9784-9806, 2020
682020
Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin
HD a. Cole, JA Roque, G Shi, LM Lifshits, E Ramasamy, PC Barrett, ...
Journal of the American Chemical Society, 2021
512021
TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models
Q Chen, V Ramu, Y Aydar, A Groenewoud, XQ Zhou, MJ Jager, H Cole, ...
Cancers 12 (3), 587, 2020
392020
Os (II) oligothienyl complexes as a hypoxia-active photosensitizer class for photodynamic therapy
JA Roque III, PC Barrett, HD Cole, LM Lifshits, E Bradner, G Shi, ...
Inorganic chemistry 59 (22), 16341-16360, 2020
382020
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia
JA Roque III, HD Cole, PC Barrett, LM Lifshits, RO Hodges, S Kim, ...
Journal of the American Chemical Society 144 (18), 8317-8336, 2022
342022
TLD1433-Mediated photodynamic therapy with an optical surface applicator in the treatment of lung cancer cells in vitro
S Chamberlain, HD Cole, J Roque III, D Bellnier, SA McFarland, ...
Pharmaceuticals 13 (7), 137, 2020
282020
Discovery of immunogenic cell death-inducing ruthenium-based photosensitizers for anticancer photodynamic therapy
P Konda, LM Lifshits, JA Roque III, HD Cole, CG Cameron, SA McFarland, ...
Oncoimmunology 10 (1), 1863626, 2021
262021
Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity
HD Cole, JA Roque III, LM Lifshits, R Hodges, PC Barrett, D Havrylyuk, ...
Photochemistry and photobiology 98 (1), 73-84, 2022
212022
Singlet Oxygen Formation vs Photodissociation for Light-Responsive Protic Ruthenium Anticancer Compounds: The Oxygenated Substituent Determines Which Pathway Dominates
F Qu, RW Lamb, CG Cameron, S Park, O Oladipupo, JL Gray, Y Xu, ...
Inorganic chemistry 60 (4), 2138-2148, 2021
192021
Modification of amyloid-beta peptide aggregation via photoactivation of strained Ru (ii) polypyridyl complexes
JC Bataglioli, LMF Gomes, C Maunoir, JR Smith, HD Cole, J McCain, ...
Chemical Science 12 (21), 7510-7520, 2021
172021
It Takes Three to Tango: The Length of the Oligothiophene Chain Determines the Nature of the Long‐Lived Excited State and the Resulting Photocytotoxicity of a Ruthenium (II …
A Chettri, JA Roque III, KRA Schneider, HD Cole, CG Cameron, ...
ChemPhotoChem 5 (5), 421-425, 2021
162021
Intracellular photophysics of an osmium complex bearing an oligothiophene extended ligand
KRA Schneider, A Chettri, HD Cole, K Reglinski, J Brückmann, ...
Chemistry–A European Journal 26 (65), 14844-14851, 2020
152020
NIR‐Absorbing RuII Complexes Containing α‐Oligothiophenes for Applications in Photodynamic Therapy
LM Lifshits, JA Roque III, HD Cole, RP Thummel, CG Cameron, ...
ChemBioChem 21 (24), 3594-3607, 2020
112020
String-attached oligothiophene substituents determine the fate of excited states in ruthenium complexes for photodynamic therapy
A Chettri, KRA Schneider, HD Cole, JA Roque III, CG Cameron, ...
The Journal of Physical Chemistry A 125 (32), 6985-6994, 2021
102021
Interaction with a Biomolecule Facilitates the Formation of the Function-Determining Long-Lived Triplet State in a Ruthenium Complex for Photodynamic Therapy
A Chettri, HD Cole, JA Roque III, KRA Schneider, T Yang, CG Cameron, ...
The Journal of Physical Chemistry A 126 (8), 1336-1344, 2022
82022
Chiral resolution and absolute configuration determination of new metal-based photodynamic therapy antitumor agents
DW Armstrong, J Yu, HD Cole, SA McFarland, J Nafie
Journal of pharmaceutical and biomedical analysis 204, 114233, 2021
82021
Using Biological Photophysics to Map the Excited‐State Topology of Molecular Photosensitizers for Photodynamic Therapy
A Chettri, T Yang, HD Cole, G Shi, CG Cameron, SA McFarland, ...
Angewandte Chemie 135 (17), e202301452, 2023
62023
Insights into enantioselective separations of ionic metal complexes by sub/supercritical fluid chromatography
TT Handlovic, MF Wahab, HD Cole, N Alatrash, E Ramasamy, ...
Analytica chimica acta 1228, 340156, 2022
42022
Ru (II) Phenanthroline-Based Oligothienyl Complexes as Phototherapy Agents
HD Cole, A Vali, JA Roque III, G Shi, G Kaur, RO Hodges, ...
Inorganic Chemistry 62 (51), 21181-21200, 2023
32023
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