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Rafael Tapia-Rojo
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The work of titin protein folding as a major driver in muscle contraction
EC Eckels, R Tapia-Rojo, JA Rivas-Pardo, JM Fernández
Annual review of physiology 80, 327-351, 2018
822018
Ephemeral states in protein folding under force captured with a magnetic tweezers design
R Tapia-Rojo, EC Eckels, JM Fernández
Proceedings of the National Academy of Sciences 116 (16), 7873-7878, 2019
752019
Trigger factor chaperone acts as a mechanical foldase
S Haldar, R Tapia-Rojo, EC Eckels, J Valle-Orero, JM Fernandez
Nature communications 8 (1), 668, 2017
722017
The mechanical power of titin folding
EC Eckels, S Haldar, R Tapia-Rojo, JA Rivas-Pardo, JM Fernández
Cell reports 27 (6), 1836-1847. e4, 2019
712019
Direct observation of a coil-to-helix contraction triggered by vinculin binding to talin
R Tapia-Rojo, A Alonso-Caballero, JM Fernandez
Science Advances 6, aaz4707, 2020
592020
Talin folding as the tuning fork of cellular mechanotransduction
R Tapia-Rojo, Á Alonso-Caballero, JM Fernández
Proceedings of the National Academy of Sciences 117 (35), 21346-21353, 2020
582020
Mechanical deformation accelerates protein ageing
J Valle‐Orero, JA Rivas‐Pardo, R Tapia‐Rojo, I Popa, DJ Echelman, ...
Angewandte Chemie International Edition 56 (33), 9741-9746, 2017
512017
Thermal and mechanical properties of a DNA model with solvation barrier
R Tapia-Rojo, JJ Mazo, F Falo
Physical Review E 82 (3), 031916, 2010
452010
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
JA Rivas-Pardo, Y Li, Z Mártonfalvi, R Tapia-Rojo, A Unger, ...
Nature communications 11 (1), 2060, 2020
392020
Protein folding modulates the chemical reactivity of a Gram-positive adhesin
A Alonso-Caballero, DJ Echelman, R Tapia-Rojo, S Haldar, EC Eckels, ...
Nature Chemistry, 1-10, 2020
372020
Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins
JA Rivas-Pardo, CL Badilla, R Tapia-Rojo, Á Alonso-Caballero, ...
Proceedings of the National Academy of Sciences 115 (37), 9222-9227, 2018
262018
Proteins breaking bad: A free energy perspective
J Valle-Orero, R Tapia-Rojo, EC Eckels, JA Rivas-Pardo, I Popa, ...
The journal of physical chemistry letters 8 (15), 3642-3647, 2017
242017
Mesoscopic model for free-energy-landscape analysis of DNA sequences
R Tapia-Rojo, D Prada-Gracia, JJ Mazo, F Falo
Physical Review E 86 (2), 021908, 2012
242012
Enhanced statistical sampling reveals microscopic complexity in the talin mechanosensor folding energy landscape
R Tapia-Rojo, M Mora, S Board, J Walker, R Boujemaa-Paterski, ...
Nature physics 19 (1), 52-60, 2023
182023
Mesoscopic model and free energy landscape for protein-DNA binding sites: analysis of cyanobacterial promoters
R Tapia-Rojo, JJ Mazo, JÁ Hernández, ML Peleato, MF Fillat, F Falo
PLoS Computational Biology 10 (10), e1003835, 2014
172014
A physical picture for mechanical dissociation of biological complexes: from forces to free energies
R Tapia-Rojo, C Marcuello, A Lostao, C Gómez-Moreno, JJ Mazo, F Falo
Physical Chemistry Chemical Physics 19 (6), 4567-4575, 2017
152017
Allosteric activation of vinculin by talin
F Franz, R Tapia-Rojo, S Winograd-Katz, R Boujemaa-Paterski, W Li, ...
Nature Communications 14 (1), 4311, 2023
112023
Magnetic tweezers meets AFM: Ultra-stable protein dynamics across the force spectrum
A Alonso-Caballero, R Tapia-Rojo, CL Badilla, JM Fernandez
bioRxiv, 2021.01. 04.425265, 2021
72021
Thermal versus mechanical unfolding in a model protein
R Tapia-Rojo, JJ Mazo, F Falo
The Journal of Chemical Physics 151 (18), 2019
72019
Identical sequences, different behaviors: Protein diversity captured at the single-molecule level
R Tapia-Rojo, A Alonso-Caballero, CL Badilla, JM Fernandez
Biophysical Journal, 2024
52024
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