Morris F White

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198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024239 317 461 637 571 726 855 1191 1540 1705 1848 2034 2234 2085 2012 2313 2364 2137 2479 2864 2625 2795 2828 3005 2773 2812 3112 2933 3019 2742 2642 2396 2393 2089 2094 2259 1974 1843 1242

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C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolVerified email at joslin.harvard.edu
Martin MyersUniversity of MichiganVerified email at umich.edu
Xiao Jian SunThe University of MarylandVerified email at medicine.umaryland.edu
Lynne YenushProfesor Departamento de Biotecnología Universidad Politécnica de ValenciaVerified email at ibmcp.upv.es
Steven ShoelsonHarvard Medical SchoolVerified email at joslin.harvard.edu
Gerald I ShulmanYale School of Medicine/Howard Hughes Medical InstituteVerified email at yale.edu
Sebastian PonsInstituto de Biología Molecular de BarcelonaVerified email at ibmb.csic.es
Zhiyong ChengUniversity of FloridaVerified email at ufl.edu
Shaodong GuoTexas A&M University, College Station, Texas USAVerified email at tamu.edu
Barry J. GoldsteinVice President and Therapeutic Area Head, Covance, IncVerified email at covance.com
Bruce M. SpiegelmanStanley J. Korsmeyer Professor, Harvard Medical School and Dana-Farber Cancer InstituteVerified email at dfci.harvard.edu
Liangyou RuiLouis G. D'Alecy Collegiate Professor of Physiology, University of Michigan Medical SchoolVerified email at umich.edu
Hans-Ulrich HäringProfessor of Endocrinology and DiabetologyVerified email at med.uni-tuebingen.de
X. Charlie DongIndiana University School of MedicineVerified email at iu.edu
Marianna SadagurskiWayne State UniversityVerified email at wayne.edu
John BlenisProfessor of Pharmacology, Weill Cornell MedicineVerified email at med.cornell.edu
Stephen PrevisMerckVerified email at merck.com
Joseph SchlessingerYale university School of MedicineVerified email at Yale.edu
Susan Bonner-Weir , Susan Bonner W...Joslin Diabetes Center, Harvard Medical SchoolVerified email at joslin.harvard.edu
Sunmin ParkHoseo UniversityVerified email at hoseo.edu

Morris F White

Professor of Pediatrics, Harvard Medical School

Verified email at childrens.harvard.edu - Homepage

insulin action insulin diabetes


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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance GS Hotamisligil, P Peraldi, A Budavari, R Ellis, MF White, BM Spiegelman Science 271 (5249), 665-670, 1996	3689	1996
Disruption of IRS-2 causes type 2 diabetes in mice DJ Withers, JS Gutierrez, H Towery, DJ Burks, JM Ren, S Previs, Y Zhang, ... Nature 391 (6670), 900-904, 1998	2167	1998
The insulin signaling system. MF White, CR Kahn Journal of Biological Chemistry 269 (1), 1-4, 1994	2115	1994
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein XJ Sun, P Rothenberg, CR Kahn, JM Backer, E Araki, PA Wilden, ... Nature 352 (6330), 73-77, 1991	2056	1991
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle C Yu, Y Chen, GW Cline, D Zhang, H Zong, Y Wang, R Bergeron, JK Kim, ... Journal of Biological Chemistry 277 (52), 50230-50236, 2002	1959	2002
The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307 V Aguirre, T Uchida, L Yenush, R Davis, MF White Journal of Biological Chemistry 275 (12), 9047-9054, 2000	1956	2000
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. ME Griffin, MJ Marcucci, GW Cline, K Bell, N Barucci, D Lee, LJ Goodyear, ... Diabetes 48 (6), 1270-1274, 1999	1714	1999
IRS proteins and the common path to diabetes MF White American Journal of Physiology-Endocrinology and Metabolism 283 (3), E413-E422, 2002	1319	2002
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action V Aguirre, ED Werner, J Giraud, YH Lee, SE Shoelson, MF White Journal of Biological Chemistry 277 (2), 1531-1537, 2002	1285	2002
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 L Rui, M Yuan, D Frantz, S Shoelson, MF White Journal of Biological Chemistry 277 (44), 42394-42398, 2002	1202	2002
Role of IRS-2 in insulin and cytokine signalling XJ Sun, LM Wang, Y Zhang, L Yenush, MG Myers Jr, E Glasheen, ... Nature 377 (6545), 173-177, 1995	1168	1995
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 KD Copps, MF White Diabetologia 55, 2565-2582, 2012	1141	2012
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents K Morino, KF Petersen, S Dufour, D Befroy, J Frattini, N Shatzkes, ... The Journal of clinical investigation 115 (12), 3587-3593, 2005	1042	2005
The IRS-signalling system: a network of docking proteins that mediate insulin action MF White Insulin Action, 3-11, 1998	1015	1998
Insulin signaling in health and disease MF White Science 302 (5651), 1710-1711, 2003	945	2003
The SH2/SH3 domain‐containing protein GRB2 interacts with tyrosine‐phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. EY Skolnik, CH Lee, A Batzer, LM Vicentini, M Zhou, R Daly, MJ Myers Jr, ... The EMBO journal 12 (5), 1929-1936, 1993	866	1993
Insulin rapidly stimulates tyrosine phosphorylation of a M_r-185,000 protein in intact cells MF White, R Maron, CR Kahn Nature 318 (6042), 183-186, 1985	863	1985
The insulin signalling system and the IRS proteins MF White Diabetologia 40, S2-S17, 1997	804	1997
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats ZY Jiang, YW Lin, A Clemont, EP Feener, KD Hein, M Igarashi, ... The Journal of clinical investigation 104 (4), 447-457, 1999	793	1999
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity DR Kaplan, M Whitman, B Schaffhausen, DC Pallas, M White, L Cantley, ... Cell 50 (7), 1021-1029, 1987	788	1987

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