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Yanier Nunez-Figueredo
Yanier Nunez-Figueredo
Drug Research and Development Center
Dirección de correo verificada de cidem.cu
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The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler
GL Pardo-Andreu, Y Nuñez-Figueredo, VG Tudella, O Cuesta-Rubio, ...
Mitochondrion 11 (2), 255-263, 2011
662011
The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications
GL Pardo-Andreu, Y Nuñez-Figueredo, VG Tudella, O Cuesta-Rubio, ...
Toxicology and applied pharmacology 253 (3), 282-289, 2011
542011
A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo
Y Nunez-Figueredo, J Ramírez-Sánchez, G Hansel, ENS Pires, N Merino, ...
Neuropharmacology 85, 517-527, 2014
522014
JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro
Y Nuñez-Figueredo, J Ramírez-Sánchez, R Delgado-Hernández, ...
European Journal of Pharmacology 726, 57-65, 2014
432014
Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment
Y Nunez-Figueredo, GL Pardo-Andreu, J Ramírez-Sánchez, ...
Brain research bulletin 109, 68-76, 2014
412014
Mitochondrial involvement in memory impairment induced by scopolamine in rats
M Wong-Guerra, J Jiménez-Martin, GL Pardo-Andreu, ...
Neurological research 39 (7), 649-659, 2017
392017
Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death
FHZ Reis, GL Pardo-Andreu, Y Nuñez-Figueredo, O Cuesta-Rubio, ...
Chemico-biological interactions 212, 20-29, 2014
362014
Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway
J Ramírez-Sánchez, ENS Pires, Y Nuñez-Figueredo, GL Pardo-Andreu, ...
Neurochemistry international 90, 215-223, 2015
342015
Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule
YN Figueredo, EO Rodríguez, YV Reyes, CC Domínguez, AL Parra, ...
Neurological research 35 (8), 804-812, 2013
292013
JM-20 treatment after MCAO reduced astrocyte reactivity and neuronal death on peri-infarct regions of the rat brain
J Ramírez-Sánchez, ENS Pires, A Meneghetti, G Hansel, ...
Molecular neurobiology 56, 502-512, 2019
252019
A strong protective action of guttiferone-A, a naturally occurring prenylated benzophenone, against iron-induced neuronal cell damage
YN Figueredo, L García-Pupo, OC Rubio, RD Hernández, Z Naal, C Curti, ...
Journal of pharmacological sciences 116 (1), 36-46, 2011
242011
The cytotoxic effects of brown Cuban propolis depend on the nemorosone content and may be mediated by mitochondrial uncoupling
GLP Andreu, FHZ Reis, FM Dalalio, YN Figueredo, OC Rubio, ...
Chemico-Biological Interactions 228, 28-34, 2015
222015
The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain
Y Nuñez-Figueredo, GLP Andreu, SO Loureiro, M Ganzella, ...
Neurochemistry international 81, 41-47, 2015
222015
JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment
M Wong-Guerra, J Jiménez-Martin, LA Fonseca-Fonseca, ...
Neurological research 41 (5), 385-398, 2019
172019
Efecto antiinflamatorio preclínico del polvo seco de Caléndula officinalis
YN FIGUEREDO, CM ALARCÓN, SA FERNÁNDEZ, AM CERNUDA
Latin American Journal of Pharmacy 26 (4), 548-52, 2007
172007
JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease
LA Fonseca-Fonseca, M Wong-Guerra, J Ramírez-Sánchez, ...
Neuroscience letters 690, 29-35, 2019
152019
Amburana cearensis seed extract protects brain mitochondria from oxidative stress and cerebellar cells from excitotoxicity induced by glutamate
ÉPL Pereira, CS Souza, J Amparo, RS Ferreira, Y Nuñez-Figueredo, ...
Journal of Ethnopharmacology 209, 157-166, 2017
152017
Discerning the antioxidant mechanism of rapanone: A naturally occurring benzoquinone with iron complexing and radical scavenging activities
K de la Vega-Hernández, M Antuch, O Cuesta-Rubio, Y Núñez-Figueredo, ...
Journal of Inorganic Biochemistry 170, 134-147, 2017
142017
Potencial terapéutico de los canabinoides como neuroprotectores
L Martínez García, JE Tacoronte Morales, Y Nuñez Figueredo, ...
Revista Cubana de Farmacia 41 (3), 0-0, 2007
142007
Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources
FDA da Silva, PA Nogara, E Ochoa-Rodríguez, Y Nuñez-Figueredo, ...
Biochimie 168, 297-306, 2020
132020
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Artículos 1–20