The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth LH Schmidt, T Spieker, S Koschmieder, J Humberg, D Jungen, E Bulk, ... Journal of thoracic oncology 6 (12), 1984-1992, 2011 | 665 | 2011 |
Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet T Barbui, A Tefferi, AM Vannucchi, F Passamonti, RT Silver, R Hoffman, ... Leukemia 32 (5), 1057-1069, 2018 | 549 | 2018 |
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival A Hamilton, GV Helgason, M Schemionek, B Zhang, S Myssina, EK Allan, ... Blood, The Journal of the American Society of Hematology 119 (6), 1501-1510, 2012 | 487 | 2012 |
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes U Krug, C Röllig, A Koschmieder, A Heinecke, MC Sauerland, M Schaich, ... The Lancet 376 (9757), 2000-2008, 2010 | 348 | 2010 |
PU. 1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis G Huang, P Zhang, H Hirai, S Elf, X Yan, Z Chen, S Koschmieder, ... Nature genetics 40 (1), 51-60, 2008 | 293 | 2008 |
Dysregulation of the C/EBPα differentiation pathway in human cancer S Koschmieder, B Halmos, E Levantini, DG Tenen Journal of clinical oncology 27 (4), 619, 2009 | 273 | 2009 |
Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study H Gisslinger, C Klade, P Georgiev, D Krochmalczyk, ... The Lancet Haematology 7 (3), e196-e208, 2020 | 262 | 2020 |
Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis S Koschmieder, B Göttgens, P Zhang, J Iwasaki-Arai, K Akashi, JL Kutok, ... Blood 105 (1), 324-334, 2005 | 261 | 2005 |
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ... The Journal of clinical investigation 123 (10), 4144-4157, 2013 | 259 | 2013 |
Flt3-dependent transformation by inactivating c-Cbl mutations in AML B Sargin, C Choudhary, N Crosetto, MHH Schmidt, R Grundler, ... Blood, The Journal of the American Society of Hematology 110 (3), 1004-1012, 2007 | 256 | 2007 |
Bleeding, thrombosis, and anticoagulation in myeloproliferative neoplasms (MPN): analysis from the German SAL-MPN-registry A Kaifie, M Kirschner, D Wolf, C Maintz, M Hänel, N Gattermann, ... Journal of hematology & oncology 9, 1-11, 2016 | 195 | 2016 |
JAK inhibition impairs NK cell function in myeloproliferative neoplasms K Schönberg, J Rudolph, M Vonnahme, S Parampalli Yajnanarayana, ... Cancer research 75 (11), 2187-2199, 2015 | 185 | 2015 |
Dexamethasone nanomedicines for COVID-19 T Lammers, AM Sofias, R Van der Meel, R Schiffelers, G Storm, F Tacke, ... Nature nanotechnology 15 (8), 622-624, 2020 | 171 | 2020 |
IL-18 activates STAT3 in the natural killer cell line 92, augments cytotoxic activity, and mediates IFN-γ production by the stress kinase p38 and by the extracellular regulated … U Kalina, D Kauschat, N Koyama, H Nuernberger, K Ballas, ... The Journal of Immunology 165 (3), 1307-1313, 2000 | 170 | 2000 |
Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both S Koschmieder, TI Mughal, HC Hasselbalch, G Barosi, P Valent, ... Leukemia 30 (5), 1018-1024, 2016 | 156 | 2016 |
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia U Steidl, C Steidl, A Ebralidze, B Chapuy, HJ Han, B Will, F Rosenbauer, ... The Journal of clinical investigation 117 (9), 2611-2620, 2007 | 147 | 2007 |
The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia S Agrawal, WK Hofmann, N Tidow, M Ehrich, D Boom, S Koschmieder, ... Blood 109 (9), 3895-3905, 2007 | 145 | 2007 |
S100A2 induces metastasis in non–small cell lung cancer E Bulk, B Sargin, U Krug, A Hascher, Y Jun, M Knop, C Kerkhoff, V Gerke, ... Clinical Cancer Research 15 (1), 22-29, 2009 | 142 | 2009 |
DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia S Agrawal, M Unterberg, S Koschmieder, U zur Stadt, U Brunnberg, ... Cancer research 67 (3), 1370-1377, 2007 | 140 | 2007 |
Effect of transcription-factor concentrations on leukemic stem cells F Rosenbauer, S Koschmieder, U Steidl, DG Tenen Blood 106 (5), 1519-1524, 2005 | 137 | 2005 |