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Alexandra Surcel
Alexandra Surcel
Department of Cell Biology, Johns Hopkins School of Medicine
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Entosis is induced by glucose starvation
JC Hamann, A Surcel, R Chen, C Teragawa, JG Albeck, DN Robinson, ...
Cell reports 20 (1), 201-210, 2017
1552017
14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis
Q Zhou, YS Kee, CC Poirier, C Jelinek, J Osborne, S Divi, A Surcel, ...
Current Biology 20 (21), 1881-1889, 2010
992010
Pharmacological activation of myosin II paralogs to correct cell mechanics defects
A Surcel, WP Ng, H West-Foyle, Q Zhu, Y Ren, LB Avery, AK Krenc, ...
Proceedings of the National Academy of Sciences 112 (5), 1428-1433, 2015
672015
Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14
A Surcel, ES Schiffhauer, DG Thomas, Q Zhu, K DiNapoli, M Herbig, ...
Biophysical Journal 116 (3), 260a, 2019
592019
Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization
H Bai, Q Zhu, A Surcel, T Luo, Y Ren, B Guan, Y Liu, N Wu, NE Joseph, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (3 …, 2016
422016
Cytokinesis through biochemical–mechanical feedback loops
A Surcel, YS Kee, T Luo, DN Robinson
Seminars in cell & developmental biology 21 (9), 866-873, 2010
402010
4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis
DS Bryan, M Stack, K Krysztofiak, U Cichoń, DG Thomas, A Surcel, ...
Proceedings of the National Academy of Sciences 117 (36), 22423-22429, 2020
322020
Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure
A Surcel, D Koshland, H Ma, RT Simpson
PLoS One 3 (6), e2453, 2008
272008
7.5 Understanding how dividing cells change shape
DN Robinson, YS Kee, T Luo, A Surcel
Comprehensive Biophysics. Amsterdam: Elsevier, 48-72, 2012
262012
Genetic suppression of a phosphomimic myosin II identifies system-level factors that promote myosin II cleavage furrow accumulation
Y Ren, H West-Foyle, A Surcel, C Miller, DN Robinson
Molecular biology of the cell 25 (25), 4150-4165, 2014
192014
Comprehensive Biophysics
DN Robinson, YS Kee, T Luo, A Surcel, EH Egelman
Academic 7, 48-73, 2012
172012
The mechanobiome: a goldmine for cancer therapeutics
E Parajón, A Surcel, DN Robinson
American Journal of Physiology-Cell Physiology 320 (3), C306-C323, 2021
152021
Long-term maintenance of stable copy number in the eukaryotic SMC family: origin of a vertebrate meiotic SMC1 and fate of recent segmental duplicates
A Surcel, X Zhou, L Quan, H Ma
Journal of Systematics and Evolution 46 (3), 405-423, 2008
102008
Meddling with myosin’s mechanobiology in cancer
A Surcel, DN Robinson
Proceedings of the National Academy of Sciences 116 (31), 15322-15323, 2019
82019
Harnessing the adaptive potential of mechanoresponsive proteins to overwhelm pancreatic cancer dissemination and invasion
A Surcel, E Schiffhauer, D Thomas, Q Zhu, K DiNapoli, M Herbig, O Otto, ...
BioRxiv, 190553, 2017
72017
Treating and preventing diseases by modulating cell mechanics
D Robinson, A Surcel, WP Ng, CLF Meyers
US Patent 11,834,401, 2023
2023
Treating and preventing diseases by modulating cell mechanics
D Robinson, A Surcel, WP Ng, CLF Meyers
US Patent 10,787,410, 2020
2020
4-Hydroxyacetophenone Modulates the Cytoskeleton through Nonmuscle Myosin-2C to Reduce Metastasis
D Bryan, M Stack, K Krysztofiak, U Cichoń, D Thomas, A Surcel, ...
Biophysical Journal 116 (3), 548a, 2019
2019
Computer Aided Small Molecule Modulation of Pancreatic Cancer Mechanobiology
KT DiNapoli, E Schiffhauer, A Surcel, D Thomas, P Iglesias, D Robinson
Biophysical Journal 116 (3), 415a, 2019
2019
The mechanobiome of pancreatic cancer: a viable, targetable drug space
A Surcel, ES Schiffhauer, D Thomas, Q Zhu, R Anders, D Robinson
Cancer Research 77 (13_Supplement), 901-901, 2017
2017
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