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Justine Sinnaeve
Justine Sinnaeve
Ashfiled Health
Dirección de correo verificada de vanderbilt.edu
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Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library
S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ...
Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017
1322017
Single cell analysis of human tissues and solid tumors with mass cytometry
N Leelatian, DB Doxie, AR Greenplate, BC Mobley, JM Lehman, ...
Cytometry Part B: Clinical Cytometry 92 (1), 68-78, 2017
1112017
Preparing viable single cells from human tissue and tumors for cytomic analysis
N Leelatian, DB Doxie, AR Greenplate, J Sinnaeve, RA Ihrie, JM Irish
Current protocols in molecular biology 118 (1), 25C. 1.1-25C. 1.23, 2017
552017
Space invaders: brain tumor exploitation of the stem cell niche
J Sinnaeve, BC Mobley, RA Ihrie
The American journal of pathology 188 (1), 29-38, 2018
242018
Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells
N Leelatian, J Sinnaeve, AM Mistry, SM Barone, AA Brockman, ...
Elife 9, e56879, 2020
202020
DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons
LK Klofas, BP Short, JP Snow, J Sinnaeve, GV Rushing, G Westlake, ...
Neurobiology of disease 143, 104975, 2020
192020
Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin
B Singh, G Bogatcheva, A Starchenko, J Sinnaeve, LA Lapierre, ...
Journal of Cell Science 128 (18), 3444-3455, 2015
122015
High risk glioblastoma cells revealed by machine learning and single cell signaling profiles
N Leelatian, J Sinnaeve, AM Mistry, SM Barone, KE Diggins, ...
bioRxiv, 632208, 2019
32019
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas
T Bartkowiak, SM Lima, MJ Hayes, AM Mistry, AA Brockman, J Sinnaeve, ...
JCI insight 8 (12), 2023
22023
IMMU-16. TWO DISTINCT SUBSETS OF NATURAL KILLER CELLS ARE ENRICHED IN THE TUMOR MICROENVIRONMENT AND CORRELATE WITH SURVIVAL OUTCOME IN HUMAN GLIOBLASTOMA.
T Bartkowiak, S Barone, M Hayes, C Roe, J Sinnaeve, A Mistry, ...
Neuro-Oncology 22 (Supplement_2), ii107-ii108, 2020
12020
CSIG-19. DETECTION OF IDH1 R132H VIA FLOW CYTOMETRY IN INTRAOPERATIVE AND ARCHIVAL GLIOMA SPECIMENS
IN IDH, WT GRADE II
Neuro-Oncology, 2018
12018
Mass cytometry of human glioblastoma characterizes more than 99 percent of cells and reveals intratumoral cell subsets defined by contrasting signaling network profiles
N Leelatian, J Sinnaeve, BC Mobley, AM Mistry, D Liu, KD Weaver, ...
Cancer Research 77 (13_Supplement), 364-364, 2017
12017
TMIC-26. USING INTEGRATED MULTIDIMENSIONAL MASS CYTOMETRY AND MULTIPLEX IMMUNOHISTOCHEMISTRY TO INFER SPATIAL RELATIONSHIPS BETWEEN PHENOTYPICALLY DISTINCT GLIOBLASTOMA …
T Bartkowiak, A Brockman, S Lima, M Hayes, C Roe, J Sinnaeve, A Mistry, ...
Neuro-Oncology 24 (Supplement_7), vii277-vii277, 2022
2022
Immune cell regulation in stem cell niche contacting glioblastomas
T Bartkowiak, SM Lima, MJ Hayes, AM Mistry, J Sinnaeve, N Leelatian, ...
bioRxiv, 2022.02. 16.480731, 2022
2022
111 Integrating multidimensional mass cytometry and multiplex immunohistochemistry to infer spatial relationships between human glioblastoma infiltrating immune cells that …
T Bartkowiak, A Brockman, S Lima, M Hayes, C Roe, J Sinnaeve, A Mistry, ...
J Immunother 10 (2), A1-A1595, 2022
2022
SELECTIVE ENRICHMENT OF SUPPRESSED IMMUNE CELLS IN THE TUMOR MICROENVIRONMENT CORRELATES WITH ESTABLISHMENT OF DISTINCT IMMUNOLOGIC NICHES IN HUMAN GLIOBLASTOMAS CONTACTING THE …
T Bartkowiak, A Brockman, B Mobley, A Mistry, S Barone, M Hayes, C Roe, ...
NEURO-ONCOLOGY 23, 94-94, 2021
2021
38 Spatial immune profiling of human glioblastoma tissue reveals the presence of aggregated lymphoid niches in the tumor microenvironment
T Bartkowiak, A Brockman, S Barone, M Hayes, C Roe, J Sinnaeve, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A45-A45, 2021
2021
661 Five immunotypic signatures identified in human glioblastoma correlate with tumor contact with the lateral ventricle, immune suppression, and patient outcome
T Bartkowiak, S Barone, M Hayes, A Greenplate, J Sinnaeve, N Leelatian, ...
Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020
2020
Single-cell systems neuroimmunology reveals a highly immunosuppressive microenvironment in human glioblastomas contacting the ventricular stem cell niche
T Bartkowiak, S Barone, AM Mistry, AR Greenplate, J Sinnaeve, ...
The Journal of Immunology 204 (1_Supplement), 242.23-242.23, 2020
2020
Single Cell Studies of Protein Expression Reveal Glioma Cell Phenotypes and Prognostic Tumor Cell Populations
J Sinnaeve
Vanderbilt University, 2020
2020
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