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Sahba Seddighi
Sahba Seddighi
MD/PhD Student, Johns Hopkins School of Medicine
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ...
Nature 603 (7899), 131-137, 2022
2102022
Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway
VR Varma, S Varma, Y An, TJ Hohman, S Seddighi, R Casanova, A Beri, ...
Molecular psychiatry 22 (1), 13-23, 2017
1252017
Social play in juvenile hamsters alters dendritic morphology in the medial prefrontal cortex and attenuates effects of social stress in adulthood.
CA Burleson, RW Pedersen, S Seddighi, LE DeBusk, GM Burghardt, ...
Behavioral Neuroscience 130 (4), 437, 2016
702016
At the crossroads between neurodegeneration and cancer: a review of overlapping biology and its implications
AL Houck, S Seddighi, JA Driver
Current aging science 11 (2), 77-89, 2018
662018
Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD
S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, ...
Science Translational Medicine 16 (734), eadg7162, 2024
372024
Evidence of a Causal Association Between Cancer and Alzheimer's Disease: a Mendelian Randomization Analysis
S Seddighi, AL Houck, JB Rowe, PDP Pharoah
Scientific Reports, 2019
292019
SPARCL1 accelerates symptom onset in Alzheimer’s disease and influences brain structure and function during aging
S Seddighi, VR Varma, Y An, S Varma, LL Beason-Held, T Tanaka, ...
Journal of Alzheimer's disease 61 (1), 401-414, 2018
272018
α2-macroglobulin in Alzheimer's disease: new roles for an old chaperone
S Seddighi, V Varma, M Thambisetty
Biomarkers in Medicine 12 (4), 311-314, 2018
122018
Dominance status alters restraint-induced neural activity in brain regions controlling stress vulnerability
MA Cooper, S Seddighi, AK Barnes, JA Grizzell, BN Dulka, CT Clinard
Physiology & behavior 179, 153-161, 2017
112017
Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders
S Diaz-Torres, W He, J Thorp, S Seddighi, S Mullany, CJ Hammond, ...
EBioMedicine 92, 2023
82023
Variant biomarker discovery using mass spectrometry-based proteogenomics
L Reilly*, S Seddighi*, AB Singleton, MR Cookson, ME Ward, YA Qi
Frontiers in Aging 4, 2023
12023
FTLD targets brain regions expressing recently evolved genes
L Pasquini, FL Pereira, S Seddighi, Y Zeng, Y Wei, I Illán-Gala, ...
medRxiv, 2023
2023
Proteogenomic Identification of TDP-43-Related Splicing Biomarkers in Frontotemporal Dementia
S Seddighi, A Qi, AL Brown, C Bereda, Y Zhang, M Prudencio, S Hill, ...
Alzheimer's Association International Conference, 2023
2023
Developing biomarkers of TDP‐43‐related splicing dysfunction in frontotemporal dementia
S Seddighi, S Hill, AL Brown, A Qi, J Hawrot, S Coon, L Petrucelli, P Fratta, ...
Alzheimer's & Dementia 17, e055170, 2021
2021
Evidence of a Causal Association Between Cancer and Alzheimer’s Disease: A Mendelian Randomization Analysis (2597)
S Seddighi, A Houck, J Rowe, P Pharoah
Neurology 94 (15_supplement), 2597, 2020
2020
Sparcl1 Accelerates Symptom Onset in Alzheimer’s Disease and Influences Brain Structure and Function During Aging
S Seddighi, VR Varma, Y An, S Varma, LL Beason-Held, T Tanaka, ...
Alzheimer's & Dementia 13 (7), P974-P975, 2017
2017
Social Status Modulates Restraint-Induced Neural Activity in Brain Regions Controlling Stress Vulnerability
S Seddighi, MA Cooper
TRACE: Tennessee Research and Creative Exchange, 2017
2017
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