Karen Doyle
Karen Doyle
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Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
KM Doyle, D Kennedy, AM Gorman, S Gupta, SJM Healy, A Samali
Journal of cellular and molecular medicine 15 (10), 2025-2039, 2011
Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia
J Li, KM Doyle, T Tatlisumak
Current medicinal chemistry 14 (17), 1807-1813, 2007
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots
S Fitzgerald, S Wang, D Dai, DH Murphree Jr, A Pandit, A Douglas, ...
PloS one 14 (12), e0225841, 2019
Platelet-rich emboli in cerebral large vessel occlusion are associated with a large artery atherosclerosis source
S Fitzgerald, D Dai, S Wang, A Douglas, R Kadirvel, KF Layton, ...
Stroke 50 (7), 1907-1910, 2019
Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex
WM Purcell, KM Doyle, C Westgate, CK Atterwill
Journal of neuroimmunology 65 (1), 49-53, 1996
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT
ST Fitzgerald, S Wang, D Dai, A Douglas, R Kadirvel, MJ Gounis, J Chueh, ...
Journal of neurointerventional surgery 11 (11), 1145-1149, 2019
Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour
KM Doyle, S Feerick, DL Kirkby, A Eddleston, GA Higgins
Behavioural pharmacology 9 (8), 671-681, 1998
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
K Mnich, LA Carleton, ET Kavanagh, KM Doyle, A Samali, AM Gorman
Cell death & disease 5 (5), e1202-e1202, 2014
Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology
W Brinjikji, RG Nogueira, P Kvamme, KF Layton, JED Almandoz, ...
Journal of neurointerventional surgery 13 (7), 594-598, 2021
Histological stroke clot analysis after thrombectomy: technical aspects and recommendations
S Staessens, S Fitzgerald, T Andersson, F Clarençon, F Denorme, ...
International Journal of Stroke 15 (5), 467-476, 2020
Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition
S Fitzgerald, R Rossi, OM Mereuta, D Jabrah, A Okolo, A Douglas, SM Gil, ...
Journal of neurointerventional surgery 13 (12), 1111-1116, 2021
Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes
A Douglas, S Fitzgerald, OM Mereuta, R Rossi, S O'Leary, A Pandit, ...
Journal of neurointerventional surgery 12 (6), 557-562, 2020
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does …
R Rossi, S Fitzgerald, S Molina, OM Mereuta, A Douglas, A Pandit, ...
Journal of thrombosis and thrombolysis 51, 545-551, 2021
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis
D Kennedy, K Mnich, D Oommen, R Chakravarthy, L Almeida-Souza, ...
Cell Death & Disease 8 (8), e3026-e3026, 2017
Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders
M Debnath, K Doyle, C Langan, C McDonald, B Leonard, D Cannon
Translational Neuroscience 2 (2), 121-137, 2011
Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine
ET Kavanagh, JP Loughlin, KR Herbert, P Dockery, A Samali, KM Doyle, ...
Biochemical and biophysical research communications 351 (4), 890-895, 2006
Studying stroke thrombus composition after thrombectomy: what can we learn?
S Staessens, O François, W Brinjikji, KM Doyle, P Vanacker, T Andersson, ...
Stroke 52 (11), 3718-3727, 2021
The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice
J Li, MC Henman, KM Doyle, D Strbian, BP Kirby, T Tatlisumak, GG Shaw
Brain research 1029 (1), 84-92, 2004
Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo.
KM Doyle, GG Shaw
British journal of pharmacology 117 (8), 1803, 1996
Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome
S Fitzgerald, OM Mereuta, KM Doyle, DF Kallmes, W Brinjikji
Journal of neurosurgical sciences 63 (3), 292, 2019
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Artículos 1–20