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Karen Doyle
Karen Doyle
Dirección de correo verificada de nuigalway.ie
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Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
KM Doyle, D Kennedy, AM Gorman, S Gupta, SJM Healy, A Samali
Journal of cellular and molecular medicine 15 (10), 2025-2039, 2011
3742011
Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia
J Li, KM Doyle, T Tatlisumak
Current medicinal chemistry 14 (17), 1807-1813, 2007
722007
Platelet-rich emboli in cerebral large vessel occlusion are associated with a large artery atherosclerosis source
S Fitzgerald, D Dai, S Wang, A Douglas, R Kadirvel, KF Layton, ...
Stroke 50 (7), 1907-1910, 2019
682019
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots
S Fitzgerald, S Wang, D Dai, DH Murphree Jr, A Pandit, A Douglas, ...
PloS one 14 (12), e0225841, 2019
652019
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT
ST Fitzgerald, S Wang, D Dai, A Douglas, R Kadirvel, MJ Gounis, J Chueh, ...
Journal of neurointerventional surgery 11 (11), 1145-1149, 2019
542019
Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology
W Brinjikji, RG Nogueira, P Kvamme, KF Layton, JED Almandoz, ...
Journal of neurointerventional surgery 13 (7), 594-598, 2021
512021
Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour
KM Doyle, S Feerick, DL Kirkby, A Eddleston, GA Higgins
Behavioural pharmacology 9 (8), 671-681, 1998
511998
Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex
WM Purcell, KM Doyle, C Westgate, CK Atterwill
Journal of neuroimmunology 65 (1), 49-53, 1996
511996
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
K Mnich, LA Carleton, ET Kavanagh, KM Doyle, A Samali, AM Gorman
Cell death & disease 5 (5), e1202-e1202, 2014
502014
Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition
S Fitzgerald, R Rossi, OM Mereuta, D Jabrah, A Okolo, A Douglas, SM Gil, ...
Journal of neurointerventional surgery 13 (12), 1111-1116, 2021
492021
Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes
A Douglas, S Fitzgerald, OM Mereuta, R Rossi, S O'Leary, A Pandit, ...
Journal of neurointerventional surgery 12 (6), 557-562, 2020
492020
Histological stroke clot analysis after thrombectomy: technical aspects and recommendations
S Staessens, S Fitzgerald, T Andersson, F Clarençon, F Denorme, ...
International Journal of Stroke 15 (5), 467-476, 2020
472020
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does …
R Rossi, S Fitzgerald, S Molina, OM Mereuta, A Douglas, A Pandit, ...
Journal of thrombosis and thrombolysis 51, 545-551, 2021
432021
Studying stroke thrombus composition after thrombectomy: what can we learn?
S Staessens, O François, W Brinjikji, KM Doyle, P Vanacker, T Andersson, ...
Stroke 52 (11), 3718-3727, 2021
422021
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis
D Kennedy, K Mnich, D Oommen, R Chakravarthy, L Almeida-Souza, ...
Cell Death & Disease 8 (8), e3026-e3026, 2017
392017
Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders
M Debnath, K Doyle, C Langan, C McDonald, B Leonard, D Cannon
Translational Neuroscience 2 (2), 121-137, 2011
342011
Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine
ET Kavanagh, JP Loughlin, KR Herbert, P Dockery, A Samali, KM Doyle, ...
Biochemical and biophysical research communications 351 (4), 890-895, 2006
332006
Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome
S Fitzgerald, OM Mereuta, KM Doyle, DF Kallmes, W Brinjikji
Journal of neurosurgical sciences 63 (3), 292, 2019
312019
Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives
S Patil, R Rossi, D Jabrah, K Doyle
Frontiers in medical technology 4, 748949, 2022
302022
The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice
J Li, MC Henman, KM Doyle, D Strbian, BP Kirby, T Tatlisumak, GG Shaw
Brain research 1029 (1), 84-92, 2004
292004
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