Mathew Garnett

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Ultan McDermottChief Scientist, Oncology R&D, AstraZenecaDirección de correo verificada de astrazeneca.com
Francesco IorioHuman TechnopoleDirección de correo verificada de fht.org
Julio Saez RodriguezHeidelberg UniversityDirección de correo verificada de uni-heidelberg.de
Fiona M BehanDirector, GSKDirección de correo verificada de gsk.com
Kosuke YusaProfessor, Kyoto UniversityDirección de correo verificada de infront.kyoto-u.ac.jp
Emanuel GonçalvesINESC-ID & IST - Universidade de LisboaDirección de correo verificada de tecnico.ulisboa.pt
Rizwan AnsariUniversity of CambridgeDirección de correo verificada de cam.ac.uk
Lodewyk WesselsProfessor of Computational Cancer BiologyDirección de correo verificada de nki.nl
Euan StronachGSKDirección de correo verificada de gsk.com
Daniel A HaberProfessor of Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical SchoolDirección de correo verificada de mgh.harvard.edu
Joshua E AllenOncoceuticsDirección de correo verificada de oncoceutics.com
Dieudonne J van der MeerSenior Scientist Bioinformatics - VitroScan BVDirección de correo verificada de vitroscan.nl
Patricia GreningerDirección de correo verificada de mgh.harvard.edu
David BarfordMRC Laboratory of Molecular BiologyDirección de correo verificada de mrc-lmb.cam.ac.uk
Michael P. MendenAssociate Professor, University of Melbourne, Department of Biochemistry and PharmacologyDirección de correo verificada de helmholtz-muenchen.de
Livio TrusolinoProfessor, University of Torino School of Medicine, ItalyDirección de correo verificada de ircc.it
Andrea BertottiUniversity of Torino - School of MedicineDirección de correo verificada de ircc.it
Graham Robert BignellSenior Staff Scientist, Wellcome Trust Sanger InstituteDirección de correo verificada de sanger.ac.uk
Matthew A. CoelhoWellcome Sanger InstituteDirección de correo verificada de sanger.ac.uk
Hans CleversHubrecht Institute - UtrechtDirección de correo verificada de hubrecht.eu

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Mathew Garnett

Wellcome Sanger Institute

Dirección de correo verificada de sanger.ac.uk - Página principal

cancer biology and therapeutics


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002	12992	2002
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF PTC Wan, MJ Garnett, SM Roe, S Lee, D Niculescu-Duvaz, VM Good, ... Cell 116 (6), 855-867, 2004	3369	2004
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells W Yang, J Soares, P Greninger, EJ Edelman, H Lightfoot, S Forbes, ... Nucleic acids research 41 (D1), D955-D961, 2012	3310	2012
Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012	2643	2012
Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015	2249	2015
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016	1887	2016
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ... Nature medicine 23 (12), 1424-1435, 2017	1303	2017
Guilty as charged: B-RAF is a human oncogene MJ Garnett, R Marais Cancer cell 6 (4), 313-319, 2004	1192	2004
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ... Nature 568 (7753), 511-516, 2019	1150	2019
Perturbation-response genes reveal signaling footprints in cancer gene expression M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ... Nature communications 9 (1), 20, 2018	629	2018
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ... PLoS one 8 (4), e61318, 2013	572	2013
Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization MJ Garnett, S Rana, H Paterson, D Barford, R Marais Molecular cell 20 (6), 963-969, 2005	517	2005
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ... Cell 151 (5), 937-950, 2012	495	2012
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ... Cell 167 (1), 260-274. e22, 2016	472	2016
High-content CRISPR screening C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ... Nature Reviews Methods Primers 2 (1), 1-23, 2022	448	2022
ETV6-NTRK3 Gene Fusions and Trisomy 11 Establish a Histogenetic Link between Mesoblastic Nephroma and Congenital Fibrosarcoma SR Knezevich, MJ Garnett, TJ Pysher, JB Beckwith, PE Grundy, ... Cancer research 58 (22), 5046-5048, 1998	439	1998
Characterizing mutational signatures in human cancer cell lines reveals episodic APOBEC mutagenesis M Petljak, LB Alexandrov, JS Brammeld, S Price, DC Wedge, ... Cell 176 (6), 1282-1294. e20, 2019	398	2019
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening E Driehuis, A Van Hoeck, K Moore, S Kolders, HE Francies, ... Proceedings of the National Academy of Sciences 116 (52), 26580-26590, 2019	390	2019
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019	312	2019
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics X Li, HE Francies, M Secrier, J Perner, A Miremadi, N Galeano-Dalmau, ... Nature communications 9 (1), 2983, 2018	312	2018

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