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Takao Ashikaga
Takao Ashikaga
National Institute of Health Sciences
Dirección de correo verificada de nihs.go.jp
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Assessing skin sensitization hazard in mice and men using non-animal test methods
D Urbisch, A Mehling, K Guth, T Ramirez, N Honarvar, S Kolle, ...
Regulatory Toxicology and Pharmacology 71 (2), 337-351, 2015
3522015
Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT): I. Optimization of the h-CLAT protocol
T Ashikaga, Y Yoshida, M Hirota, K Yoneyama, H Itagaki, H Sakaguchi, ...
Toxicology in vitro 20 (5), 767-773, 2006
3392006
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT) II. An inter-laboratory study of the h-CLAT
H Sakaguchi, T Ashikaga, M Miyazawa, Y Yoshida, Y Ito, K Yoneyama, ...
Toxicology in vitro 20 (5), 774-784, 2006
2422006
Categorization of chemicals according to their relative human skin sensitizing potency
DA Basketter, N Alépée, T Ashikaga, J Barroso, N Gilmour, C Goebel, ...
Dermatitis 25 (1), 11-21, 2014
2162014
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
NC Kleinstreuer, S Hoffmann, N Alépée, D Allen, T Ashikaga, W Casey, ...
Critical reviews in toxicology 48 (5), 359-374, 2018
1672018
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
S Hoffmann, N Kleinstreuer, N Alépée, D Allen, AM Api, T Ashikaga, ...
Critical reviews in toxicology 48 (5), 344-358, 2018
1522018
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment
K Reisinger, S Hoffmann, N Alépée, T Ashikaga, J Barroso, C Elcombe, ...
Toxicology in Vitro 29 (1), 259-270, 2015
1512015
A Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA)
T Ashikaga, H Sakaguchi, S Sono, N Kosaka, M Ishikawa, Y Nukada, ...
Alternatives to laboratory animals 38 (4), 275-284, 2010
1482010
Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy
JS Jaworska, A Natsch, C Ryan, J Strickland, T Ashikaga, M Miyazawa
Archives of toxicology 89, 2355-2383, 2015
1452015
Effect of the photocatalytic activity of TiO2 on plasmid DNA
T Ashikaga, M Wada, H Kobayashi, M Mori, Y Katsumura, H Fukui, S Kato, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466 (1), 1-7, 2000
1252000
The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test–human cell line activation test (h-CLAT)
H Sakaguchi, T Ashikaga, M Miyazawa, N Kosaka, Y Ito, K Yoneyama, ...
Cell biology and toxicology 25, 109-126, 2009
1202009
Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers
T Ashikaga, M Hoya, H Itagaki, Y Katsumura, S Aiba
Toxicology in Vitro 16 (6), 711-716, 2002
1182002
Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency
Y Nukada, T Ashikaga, M Miyazawa, M Hirota, H Sakaguchi, H Sasa, ...
Toxicology in vitro 26 (7), 1150-1160, 2012
1152012
Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and …
O Takenouchi, S Fukui, K Okamoto, S Kurotani, N Imai, M Fujishiro, ...
Journal of Applied Toxicology 35 (11), 1318-1332, 2015
1022015
Identifying and characterizing chemical skin sensitizers without animal testing: Colipa’s research and method development program
P Aeby, T Ashikaga, S Bessou-Touya, A Schepky, F Gerberick, P Kern, ...
Toxicology in vitro 24 (6), 1465-1473, 2010
922010
Predictive performance for human skin sensitizing potential of the human cell line activation test (h‐CLAT)
Y Nukada, T Ashikaga, H Sakaguchi, S Sono, N Mugita, M Hirota, ...
Contact dermatitis 65 (6), 343-353, 2011
852011
Predictive performance of the human Cell Line Activation Test (h-CLAT) for lipophilic chemicals with high octanol-water partition coefficients
O Takenouchi, M Miyazawa, K Saito, T Ashikaga, H Sakaguchi
The Journal of toxicological sciences 38 (4), 599-609, 2013
752013
Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring …
H Sakaguchi, C Ryan, JM Ovigne, KR Schroeder, T Ashikaga
Toxicology in Vitro 24 (6), 1810-1820, 2010
702010
Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network‐based risk assessment model of skin sensitization
M Hirota, S Fukui, K Okamoto, S Kurotani, N Imai, M Fujishiro, D Kyotani, ...
Journal of Applied Toxicology 35 (11), 1333-1347, 2015
592015
Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment
G Maxwell, P Aeby, T Ashikaga, S Bessou-Touya, W Diembeck, ...
ALTEX-Alternatives to animal experimentation 28 (1), 50-55, 2011
562011
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