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Mary Wertz
Mary Wertz
Postdoc Broad Institute/MIT
Dirección de correo verificada de mit.edu
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BACE1 regulates voltage-gated sodium channels and neuronal activity
DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ...
Nature cell biology 9 (7), 755-764, 2007
3762007
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits
B Akten, MJ Kye, LT Hao, MH Wertz, S Singh, D Nie, J Huang, ...
Proceedings of the National Academy of Sciences 108 (25), 10337-10342, 2011
2462011
SMN regulates axonal local translation via miR-183/mTOR pathway
MJ Kye, ED Niederst, MH Wertz, ICG Gonçalves, B Akten, KZ Dover, ...
Human molecular genetics 23 (23), 6318-6331, 2014
1492014
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1
A Di Nardo, MH Wertz, E Kwiatkowski, PT Tsai, JD Leech, ...
Human molecular genetics 23 (14), 3865-3874, 2014
1052014
Genome-wide in vivo CNS screening identifies genes that modify CNS neuronal survival and mHTT toxicity
MH Wertz, MR Mitchem, SS Pineda, LJ Hachigian, H Lee, V Lau, ...
Neuron 106 (1), 76-89. e8, 2020
712020
Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy
MH Wertz, K Winden, P Neveu, SY Ng, E Ercan, M Sahin
Human molecular genetics 25 (11), 2168-2181, 2016
492016
Characterization of the nuclear localization signal of high risk HPV16 E2 protein
K Klucevsek, M Wertz, J Lucchi, A Leszczynski, J Moroianu
Virology 360 (1), 191-198, 2007
252007
Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes
MH Wertz, SS Pineda, H Lee, R Kulicke, M Kellis, M Heiman
Molecular neurodegeneration 15, 1-8, 2020
222020
Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis
SW Kong, M Sahin, CD Collins, MH Wertz, MG Campbell, JD Leech, ...
Molecular Autism 5, 1-11, 2014
222014
Developing therapies for spinal muscular atrophy
MH Wertz, M Sahin
Annals of the New York Academy of Sciences 1366 (1), 5-19, 2016
212016
d. CG, Akten, B
MJ Kye, ED Niederst, MH Wertz, I Gonçalves
Dover, KZ,... Sahin, M.(2014, dec). SMN regulates axonal local translation …, 2014
122014
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin
L Megret, B Gris, S Sasidharan Nair, J Cevost, M Wertz, J Aaronson, ...
Elife 10, e64984, 2021
72021
The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells
DY Kim, MH Wertz, V Gautam, C D'avanzo, R Bhattacharyya, DM Kovacs
Neurodegenerative Diseases 13 (2-3), 64-68, 2014
52014
Genome-wide genetic screening in the mammalian CNS
MH Wertz, M Heiman
Genome Editing in Neurosciences, 31-39, 2017
22017
Neuronal Tsc1/2 Complex Controls Autophagy Through AMPK-Dependent Regulation Of ULK1
AD NARDO, MH Wertz, E Kwiatkowski, PT Tsai, JD Leech, ...
Human Molecular Genetics 23 (14), 1-10, 2014
12014
A39 Precision machine-learning identifies a new paradigm along with a target database for therapeutic discovery in Huntington’s disease: molecular reprogramming to re-instate …
L Megret, B Gris, SS Nai, J Cevost, M Wertz, J Aaronson, J Rosinski, ...
Journal of Neurology, Neurosurgery & Psychiatry 93 (Suppl 1), A14-A14, 2022
2022
A03 Precise machine-learning suggests that neuronal death in HD is mainly driven by the loss of homeostatic responses
L Mégret, B Gris, SS Nair, J Cevost, M Wertz, J Aaronson, J Rosinski, ...
Journal of Neurology, Neurosurgery & Psychiatry 92 (Suppl 1), A1-A2, 2021
2021
Aberrant microRNA expression in spinal muscular atrophy motor neurons
MH Wertz
Harvard University, 2015
2015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–18