Päivi Östling
Päivi Östling
Scientific Lead of Precision Medicine, SciLifeLab, Dept. Oncology and Pathology, Karolinska
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Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
L Pirkkala, P Nykänen, LEA Sistonen
The FASEB Journal 15 (7), 1118-1131, 2001
Screening out irrelevant cell-based models of disease
P Horvath, N Aulner, M Bickle, AM Davies, ED Nery, D Ebner, ...
Nature reviews Drug discovery 15 (11), 751-769, 2016
Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells
P Östling, SK Leivonen, A Aakula, P Kohonen, R Mäkelä, Z Hagman, ...
Cancer research 71 (5), 1956-1967, 2011
Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
SK Leivonen, R Mäkelä, P Östling, P Kohonen, S Haapa-Paananen, ...
Oncogene 28 (44), 3926-3936, 2009
Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1
P Östling, JK Björk, P Roos-Mattjus, V Mezger, L Sistonen
Journal of Biological Chemistry 282 (10), 7077-7086, 2007
Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ
S Jin, AP Mutvei, IV Chivukula, ER Andersson, D Ramsköld, R Sandberg, ...
Oncogene 32 (41), 4892-4902, 2013
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion
M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ...
Oncogene 31 (29), 3444-3456, 2012
Role of heat-shock factor 2 in cerebral cortex formation and as a regulatorof p35 expression
Y Chang, P Östling, M Åkerfelt, D Trouillet, M Rallu, Y Gitton, R El Fatimy, ...
Genes & development 20 (7), 836-847, 2006
Consistency in drug response profiling
JP Mpindi, B Yadav, P Östling, P Gautam, D Malani, A Murumägi, ...
Nature 540 (7631), E5-E6, 2016
Comprehensive drug testing of patient-derived conditionally reprogrammed cells from castration-resistant prostate cancer
K Saeed, V Rahkama, S Eldfors, D Bychkov, JP Mpindi, B Yadav, ...
European urology 71 (3), 319-327, 2017
Breeze: an integrated quality control and data analysis application for high-throughput drug screening
S Potdar, A Ianevski, JP Mpindi, D Bychkov, C Fiere, P Ianevski, B Yadav, ...
Bioinformatics 36 (11), 3602-3604, 2020
Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact
SK Leivonen, A Rokka, P Östling, P Kohonen, GL Corthals, O Kallioniemi, ...
Molecular & Cellular Proteomics 10 (7), 2011
Accurate morphology preserving segmentation of overlapping cells based on active contours
C Molnar, IH Jermyn, Z Kato, V Rahkama, P Östling, P Mikkonen, ...
Scientific reports 6 (1), 32412, 2016
Systematic identification of microRNAs that impact on proliferation of prostate cancer cells and display changed expression in tumor tissue
A Aakula, P Kohonen, SK Leivonen, R Mäkelä, P Hintsanen, JP Mpindi, ...
European urology 69 (6), 1120-1128, 2016
MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth
A Aakula, SK Leivonen, P Hintsanen, T Aittokallio, Y Ceder, ...
Molecular oncology 9 (7), 1287-1300, 2015
FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis
SP Turunen, P von Nandelstadh, T Öhman, E Gucciardo, ...
Cell Death & Differentiation 26 (12), 2577-2593, 2019
Differentiation lineage‐specific expression of human heat shock transcription factor 2
L Pirkkala, TP Alastalo, P Nykänen, L Seppä, L Sistonen
The FASEB journal 13 (9), 1089-1098, 1999
ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors
K Kaipio, P Chen, P Roering, K Huhtinen, P Mikkonen, P Östling, ...
The Journal of pathology 250 (2), 159-169, 2020
Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose–response data
JP Mpindi, P Swapnil, B Dmitrii, S Jani, K Saeed, K Wennerberg, ...
Bioinformatics 31 (23), 3815-3821, 2015
miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen
O Larne, P Östling, BS Haflidadottir, Z Hagman, A Aakula, P Kohonen, ...
European urology 68 (4), 581-588, 2015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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