Exploitation of the apoptosis-primed state of MYCN-amplified neuroblastoma to develop a potent and specific targeted therapy combination J Ham, C Costa, R Sano, TL Lochmann, EM Sennott, NU Patel, A Dastur, ... Cancer cell 29 (2), 159-172, 2016 | 125 | 2016 |
Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression TL Lochmann, KV Floros, M Naseri, KM Powell, W Cook, RJ March, ... Clinical Cancer Research 24 (2), 360-369, 2018 | 114 | 2018 |
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma TL Lochmann, KM Powell, J Ham, KV Floros, DAR Heisey, RIJ Kurupi, ... Science translational medicine 10 (441), eaao4680, 2018 | 84 | 2018 |
Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM KA Song, MJ Niederst, TL Lochmann, AN Hata, H Kitai, J Ham, KV Floros, ... Clinical Cancer Research 24 (1), 197-208, 2018 | 84 | 2018 |
Epigenetic modifications of the PGC-1α promoter during exercise induced expression in mice TL Lochmann, RR Thomas, JP Bennett Jr, SM Taylor PloS one 10 (6), e0129647, 2015 | 53 | 2015 |
Increased Synthesis of MCL-1 Protein Underlies Initial Survival of EGFR-Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target KA Song, Y Hosono, C Turner, S Jacob, TL Lochmann, Y Murakami, ... Clinical Cancer Research 24 (22), 5658-5672, 2018 | 50 | 2018 |
NC-mediated nucleolar localization of retroviral gag proteins TL Lochmann, DV Bann, EP Ryan, AR Beyer, A Mao, A Cochrane, ... Virus research 171 (2), 304-318, 2013 | 46 | 2013 |
Intermolecular interactions between retroviral Gag proteins in the nucleus SP Kenney, TL Lochmann, CL Schmid, LJ Parent Journal of virology 82 (2), 683-691, 2008 | 44 | 2008 |
Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus Gag protein S Nadaraia-Hoke, DV Bann, TL Lochmann, N Gudleski-O’Regan, ... Journal of virology, JVI. 03059-12, 2013 | 38 | 2013 |
Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy KV Floros, TL Lochmann, B Hu, C Monterrubio, MT Hughes, JD Wells, ... Proceedings of the National Academy of Sciences, 201717820, 2018 | 32 | 2018 |
The Ewing family of tumors rely on BCL-2 and BCL-XL to escape PARP inhibitor toxicity DAR Heisey, TL Lochmann, KV Floros, CM Coon, KM Powell, S Jacob, ... Clinical Cancer Research, clincanres. 0277.2018, 2018 | 31 | 2018 |
BCL-2 inhibition is a promising therapeutic strategy for small cell lung cancer TL Lochmann, YM Bouck, AC Faber Oncoscience 5 (7-8), 218, 2018 | 21 | 2018 |
Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus BL Rice, RJ Kaddis, MS Stake, TL Lochmann, LJ Parent Frontiers in microbiology 6, 925, 2015 | 11 | 2015 |
P2. 13-35 Inhibition of H3K27 Demethylation is Toxic in Poorly Differentiated Small Cell Lung Cancer T Lochmann, M Calbert, K Powell, C Benes, H Harada, A Faber Journal of Thoracic Oncology 13 (10), S812, 2018 | | 2018 |
Abstract B31: A protein synthesis switch underlies initial survival of EGFR-mutant lung cancer to EGFR inhibitors KA Song, TL Lochmann, NU Patel, J Ham, BE Windle, H Harada, ... Clinical Cancer Research 24 (17 Supplement), B31-B31, 2018 | | 2018 |