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Brian T. Do
Brian T. Do
Dirección de correo verificada de hms.harvard.edu - Página principal
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Opportunities and obstacles for deep learning in biology and medicine
T Ching, DS Himmelstein, BK Beaulieu-Jones, AA Kalinin, BT Do, ...
Journal of The Royal Society Interface, 2018
19782018
Cell-programmed nutrient partitioning in the tumour microenvironment
BI Reinfeld, MZ Madden, MM Wolf, A Chytil, JE Bader, AR Patterson, ...
Nature 593 (7858), 282-288, 2021
5882021
Increased demand for NAD+ relative to ATP drives aerobic glycolysis
A Luengo, Z Li, DY Gui, LB Sullivan, M Zagorulya, BT Do, R Ferreira, ...
Molecular cell 81 (4), 691-707. e6, 2021
2862021
irCLIP platform for efficient characterization of protein–RNA interactions
BJ Zarnegar, RA Flynn, Y Shen, BT Do, HY Chang, PA Khavari
Nature methods 13 (6), 489-492, 2016
2462016
7SK-BAF axis controls pervasive transcription at enhancers
RA Flynn, BT Do, AJ Rubin, E Calo, B Lee, H Kuchelmeister, M Rale, ...
Nature structural & molecular biology 23 (3), 231-238, 2016
1092016
Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs
GXY Zheng, BT Do, DE Webster, PA Khavari, HY Chang
Nature structural & molecular biology 21 (7), 585-590, 2014
1082014
Dissecting noncoding and pathogen RNA–protein interactomes
RA Flynn, L Martin, RC Spitale, BT Do, SM Sagan, B Zarnegar, K Qu, ...
RNA 21 (1), 135-143, 2015
892015
Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress
S Oh, RA Flynn, SN Floor, J Purzner, L Martin, BT Do, S Schubert, D Vaka, ...
Oncotarget 7 (19), 28169, 2016
802016
Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma
JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ...
Molecular cell 62 (1), 34-46, 2016
792016
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders
CE Ang, Q Ma, OL Wapinski, SH Fan, RA Flynn, QY Lee, B Coe, ...
Elife 8, e41770, 2019
712019
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
AJ Schwartz, JW Goyert, S Solanki, SA Kerk, B Chen, C Castillo, PP Hsu, ...
Nature metabolism 3 (7), 969-982, 2021
622021
Nucleotide imbalance decouples cell growth from cell proliferation
FF Diehl, TP Miettinen, R Elbashir, CS Nabel, AM Darnell, BT Do, ...
Nature cell biology 24 (8), 1252-1264, 2022
572022
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity
R Franklin, Y Guo, S He, M Chen, F Ji, X Zhou, D Frankhouser, BT Do, ...
Nature communications 13 (1), 2350, 2022
102022
Screening in serum-derived medium reveals differential response to compounds targeting metabolism
KL Abbott, A Ali, D Casalena, BT Do, R Ferreira, JH Cheah, CK Soule, ...
Cell chemical biology 30 (9), 1156-1168. e7, 2023
82023
Cancer tissue of origin constrains the growth and metabolism of metastases
S Sivanand, Y Gultekin, PS Winter, SY Vermeulen, K Tchourine, ...
bioRxiv, 2022.08. 17.504141, 2022
42022
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
BT Do, PP Hsu, SY Vermeulen, Z Wang, T Hirz, KL Abbott, N Aziz, ...
bioRxiv, 2022.08. 16.503984, 2022
42022
Loss of FLT3 sensitizes myeloid cells to differentiation Via DHODH inhibition
AN Sexauer, B Do, DB Sykes
Blood 134, 2712, 2019
32019
SherlockNet: Exploring 400 Years of Western Book Illustrations With Convolutional Neural Networks
L Zhao, K Wang, B Do
22016
GOT2 consider the tumor microenvironment
BT Do, MG Vander Heiden
Trends in cancer 8 (11), 884-886, 2022
12022
Metabolic and genetic factors guiding hematopoietic cell fate
BT Do
Massachusetts Institute of Technology, 2023
2023
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Artículos 1–20