Rational design of potent sialidase-based inhibitors of influenza virus replication M Von Itzstein, WY Wu, GB Kok, MS Pegg, JC Dyason, B Jin, T Van Phan, ... Nature 363 (6428), 418-423, 1993 | 2443 | 1993 |
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function L Chen, SN Willis, A Wei, BJ Smith, JI Fletcher, MG Hinds, PM Colman, ... Molecular cell 17 (3), 393-403, 2005 | 2272 | 2005 |
Conformations of immunoglobulin hypervariable regions C Chothia, AM Lesk, A Tramontano, M Levitt, SJ Smith-Gill, G Air, S Sheriff, ... Nature 342 (6252), 877-883, 1989 | 2012 | 1989 |
Shape complementarity at protein/protein interfaces MC Lawrence, PM Colman Journal of molecular biology 234 (4), 946-950, 1993 | 1541 | 1993 |
Effects of amino acid sequence changes on antibody-antigen interactions PM Colman Research in immunology 145 (1), 33-36, 1994 | 1305 | 1994 |
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 Å resolution JN Varghese, WG Laver, PM Colman Nature 303 (5912), 35-40, 1983 | 1173 | 1983 |
Structure of the catalytic and antigenic sites in influenza virus neuraminidase PM Colman, JN Varghese, WG Laver Nature 303 (5912), 41-44, 1983 | 1087 | 1983 |
X-ray crystal structure analysis of plastocyanin at 2.7 Å resolution PM Colman, HC Freeman, JM Guss, M Murata, VA Norris, JAM Ramshaw, ... Nature 272 (5651), 319-324, 1978 | 852 | 1978 |
BCL-2 family antagonists for cancer therapy G Lessene, PE Czabotar, PM Colman Nature reviews Drug discovery 7 (12), 989-1000, 2008 | 805 | 2008 |
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase PM Colman, WG Laver, JN Varghese, AT Baker, PA Tulloch, GM Air, ... Nature 326 (6111), 358-363, 1987 | 726 | 1987 |
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis PE Czabotar, D Westphal, G Dewson, S Ma, C Hockings, WD Fairlie, ... Cell 152 (3), 519-531, 2013 | 657 | 2013 |
The structural biology of type I viral membrane fusion PM Colman, MC Lawrence Nature Reviews Molecular Cell Biology 4 (4), 309-319, 2003 | 606 | 2003 |
Crystallographic structure studies of an IgG molecule and an Fc fragment R Huber, J Deisenhofer, PM Colman, M Matsushima, W Palm Nature 264 (5585), 415-420, 1976 | 554 | 1976 |
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor JN Varghese, JL McKimm‐Breschkin, JB Caldwell, AA Kortt, PM Colman Proteins: Structure, Function, and Bioinformatics 14 (3), 327-332, 1992 | 522 | 1992 |
Structural insights into the degradation of Mcl-1 induced by BH3 domains PE Czabotar, EF Lee, MF van Delft, CL Day, BJ Smith, DCS Huang, ... Proceedings of the National Academy of Sciences 104 (15), 6217-6222, 2007 | 516 | 2007 |
Influenza virus neuraminidase: structure, antibodies, and inhibitors PM Colman Protein Science 3 (10), 1687-1696, 1994 | 483 | 1994 |
Structure-guided design of a selective BCL-XL inhibitor G Lessene, PE Czabotar, BE Sleebs, K Zobel, KN Lowes, JM Adams, ... Nature chemical biology 9 (6), 390-397, 2013 | 443 | 2013 |
Three-dimensional structure of thermolysin BW Matthews, JN Jansonius, PM Colman, BP Schoenborn, D Dupourque Nature new biology 238, 37-41, 1972 | 438 | 1972 |
The structure of thermolysin: an electron density map at 2.3 Å resolution PM Colman, JN Jansonius, BW Matthews Journal of molecular biology 70 (3), 701-724, 1972 | 414 | 1972 |
To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3: groove interactions G Dewson, T Kratina, HW Sim, H Puthalakath, JM Adams, PM Colman, ... Molecular cell 30 (3), 369-380, 2008 | 401 | 2008 |