| Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes H Shimano, N Yahagi, M Amemiya-Kudo, AH Hasty, J Osuga, Y Tamura, ... Journal of Biological Chemistry 274 (50), 35832-35839, 1999 | 839 | 1999 |
| Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity J Osuga, S Ishibashi, T Oka, H Yagyu, R Tozawa, A Fujimoto, F Shionoiri, ... Proceedings of the National academy of sciences 97 (2), 787-792, 2000 | 724 | 2000 |
| Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter T Yoshikawa, H Shimano, M Amemiya-Kudo, N Yahagi, AH Hasty, ... Molecular and cellular biology, 2001 | 629 | 2001 |
| Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance T Matsuzaka, H Shimano, N Yahagi, T Kato, A Atsumi, T Yamamoto, ... Nature medicine 13 (10), 1193-1202, 2007 | 586 | 2007 |
| Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements T Yoshikawa, H Shimano, N Yahagi, T Ide, M Amemiya-Kudo, ... Journal of Biological Chemistry 277 (3), 1705-1711, 2002 | 517 | 2002 |
| Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression M Sekiya, N Yahagi, T Matsuzaka, Y Najima, M Nakakuki, R Nagai, ... Hepatology 38 (6), 1529-1539, 2003 | 505 | 2003 |
| Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lepob/Lepob mice N Yahagi, H Shimano, AH Hasty, T Matsuzaka, T Ide, T Yoshikawa, ... Journal of Biological Chemistry 277 (22), 19353-19357, 2002 | 468 | 2002 |
| Transcriptional activities of nuclear SREBP-1a,-1c, and-2 to different target promoters of lipogenic and cholesterogenic genes M Amemiya-Kudo, H Shimano, AH Hasty, N Yahagi, T Yoshikawa, ... Journal of lipid research 43 (8), 1220-1235, 2002 | 450 | 2002 |
| A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids N Yahagi, H Shimano, AH Hasty, M Amemiya-Kudo, H Okazaki, Y Tamura, ... Journal of Biological Chemistry 274 (50), 35840-35844, 1999 | 448 | 1999 |
| Troglitazone inhibits atherosclerosis in apolipoprotein E–knockout mice: pleiotropic effects on CD36 expression and HDL Z Chen, S Ishibashi, S Perrey, J Osuga, T Gotoda, T Kitamine, Y Tamura, ... Arteriosclerosis, thrombosis, and vascular biology 21 (3), 372-377, 2001 | 435 | 2001 |
| SREBPs suppress IRS-2-mediated insulin signalling in the liver T Ide, H Shimano, N Yahagi, T Matsuzaka, M Nakakuki, T Yamamoto, ... Nature cell biology 6 (4), 351-357, 2004 | 429 | 2004 |
| Dual regulation of mouse Δ5-and Δ6-desaturase gene expression by SREBP-1 and PPARα T Matsuzaka, H Shimano, N Yahagi, M Amemiya-Kudo, T Yoshikawa, ... Journal of lipid research 43 (1), 107-114, 2002 | 355 | 2002 |
| Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol … T Yoshikawa, T Ide, H Shimano, N Yahagi, M Amemiya-Kudo, ... Molecular Endocrinology 17 (7), 1240-1254, 2003 | 343 | 2003 |
| Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. H Abe, N Yamada, K Kamata, T Kuwaki, M Shimada, J Osuga, F Shionoiri, ... The Journal of clinical investigation 101 (8), 1784-1788, 1998 | 314 | 1998 |
| Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene M Amemiya-Kudo, H Shimano, T Yoshikawa, N Yahagi, AH Hasty, ... Journal of Biological Chemistry 275 (40), 31078-31085, 2000 | 299 | 2000 |
| Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma N Yahagi, H Shimano, K Hasegawa, K Ohashi, T Matsuzaka, Y Najima, ... European Journal of Cancer 41 (9), 1316-1322, 2005 | 279 | 2005 |
| Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor AH Hasty, H Shimano, J Osuga, I Namatame, A Takahashi, N Yahagi, ... Journal of Biological Chemistry 276 (40), 37402-37408, 2001 | 272 | 2001 |
| Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets T Kato, H Shimano, T Yamamoto, M Ishikawa, S Kumadaki, T Matsuzaka, ... Diabetes 57 (9), 2382-2392, 2008 | 257 | 2008 |
| p53 Activation in adipocytes of obese mice N Yahagi, H Shimano, T Matsuzaka, Y Najima, M Sekiya, Y Nakagawa, ... Journal of Biological Chemistry 278 (28), 25395-25400, 2003 | 249 | 2003 |
| Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs T Matsuzaka, H Shimano, N Yahagi, T Yoshikawa, M Amemiya-Kudo, ... Journal of lipid research 43 (6), 911-920, 2002 | 248 | 2002 |
Hirohito SoneNiigata University Faculty of Medicine, Dept. of Hematology, Endocrinology and MetabolismVerified email at med.niigata-u.ac.jp
