Nibaldo C. Inestrosa
Nibaldo C. Inestrosa
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Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme
NC Inestrosa, A Alvarez, CA Perez, RD Moreno, M Vicente, C Linker, ...
Neuron 16 (4), 881-891, 1996
Metalloenzyme-like activity of Alzheimer's disease β-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2
C Opazo, X Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, ...
Journal of Biological Chemistry 277 (43), 40302-40308, 2002
Settlement of benthic marine invertebrates
SR Rodriguez, FP Ojeda, NC Inestrosa
Marine ecology progress series. Oldendorf 97 (2), 193-207, 1993
Emerging roles of Wnts in the adult nervous system
NC Inestrosa, E Arenas
Nature Reviews Neuroscience 11 (2), 77-86, 2010
The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease
S Miranda, C Opazo, LF Larrondo, FJ Muñoz, F Ruiz, F Leighton, ...
Progress in neurobiology 62 (6), 633-648, 2000
A structural motif of acetylcholinesterase that promotes amyloid β-peptide fibril formation
GV De Ferrari, MA Canales, I Shin, LM Weiner, I Silman, NC Inestrosa
Biochemistry 40 (35), 10447-10457, 2001
The α-Helical to β-Strand Transition in the Amino-terminal Fragment of the Amyloid β-Peptide Modulates Amyloid Formation∗
C Soto, EM Castaño, B Frangione, NC Inestrosa
Journal of Biological Chemistry 270 (7), 3063-3067, 1995
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
GV De Ferrari, MA Chacon, MI Barria, JL Garrido, JA Godoy, G Olivares, ...
Molecular psychiatry 8 (2), 195-208, 2003
Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils
A Alvarez, R Alarcón, C Opazo, EO Campos, FJ Muñoz, FH Calderón, ...
Journal of Neuroscience 18 (9), 3213-3223, 1998
Wnt signaling function in Alzheimer’s disease
GV De Ferrari, NC Inestrosa
Brain research reviews 33 (1), 1-12, 2000
Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils
A Alvarez, C Opazo, R Alarcón, J Garrido, NC Inestrosa
Journal of molecular biology 272 (3), 348-361, 1997
Platelets are the primary source of amyloid β-peptide in human blood
M Chen, NC Inestrosa, GS Ross, HL Fernandez
Biochemical and biophysical research communications 213 (1), 96-103, 1995
Peroxisome proliferator-activated receptor γ up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative …
K Fuenzalida, R Quintanilla, P Ramos, D Piderit, RA Fuentealba, ...
Journal of Biological Chemistry 282 (51), 37006-37015, 2007
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
EM Toledo, NC Inestrosa
Molecular psychiatry 15 (3), 272-285, 2010
Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons
AR Alvarez, JA Godoy, K Mullendorff, GH Olivares, M Bronfman, ...
Experimental cell research 297 (1), 186-196, 2004
Amyloid–cholinesterase interactions: implications for Alzheimer’s disease
NC Inestrosa, MC Dinamarca, A Alvarez
The FEBS journal 275 (4), 625-632, 2008
Wnt signaling in neuroprotection and stem cell differentiation
EM Toledo, M Colombres, NC Inestrosa
Progress in neurobiology 86 (3), 281-296, 2008
Wnt signaling in the nervous system and in Alzheimer's disease
NC Inestrosa, L Varela-Nallar
Journal of molecular cell biology 6 (1), 64-74, 2014
Detection of peroxisomal fatty acyl-coenzyme A oxidase activity
NC Inestrosa, M Bronfman, F Leighton
Biochemical Journal 182 (3), 779-788, 1979
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons
W Cerpa, JA Godoy, I Alfaro, GG Farías, MJ Metcalfe, R Fuentealba, ...
Journal of Biological Chemistry 283 (9), 5918-5927, 2008
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