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Nibaldo C. Inestrosa
Nibaldo C. Inestrosa
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Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme
NC Inestrosa, A Alvarez, CA Perez, RD Moreno, M Vicente, C Linker, ...
Neuron 16 (4), 881-891, 1996
13171996
Metalloenzyme-like activity of Alzheimer's disease β-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2
C Opazo, X Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, ...
Journal of Biological Chemistry 277 (43), 40302-40308, 2002
7882002
Emerging roles of Wnts in the adult nervous system
NC Inestrosa, E Arenas
Nature Reviews Neuroscience 11 (2), 77-86, 2010
7682010
Settlement of benthic marine invertebrates
SR Rodriguez, FP Ojeda, NC Inestrosa
Marine ecology progress series. Oldendorf 97 (2), 193-207, 1993
7591993
The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease
S Miranda, C Opazo, LF Larrondo, FJ Muñoz, F Ruiz, F Leighton, ...
Progress in neurobiology 62 (6), 633-648, 2000
5232000
A structural motif of acetylcholinesterase that promotes amyloid β-peptide fibril formation
GV De Ferrari, MA Canales, I Shin, LM Weiner, I Silman, NC Inestrosa
Biochemistry 40 (35), 10447-10457, 2001
5222001
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
GV De Ferrari, MA Chacon, MI Barria, JL Garrido, JA Godoy, G Olivares, ...
Molecular psychiatry 8 (2), 195-208, 2003
4602003
Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils
A Alvarez, R Alarcon, C Opazo, EO Campos, FJ Munoz, FH Calderon, ...
Journal of Neuroscience 18 (9), 3213-3223, 1998
4401998
The α-Helical to β-Strand Transition in the Amino-terminal Fragment of the Amyloid β-Peptide Modulates Amyloid Formation∗
C Soto, EM Castano, B Frangione, NC Inestrosa
Journal of Biological Chemistry 270 (7), 3063-3067, 1995
4261995
Wnt signaling function in Alzheimer’s disease
GV De Ferrari, NC Inestrosa
Brain research reviews 33 (1), 1-12, 2000
3822000
Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils
A Alvarez, C Opazo, R Alarcón, J Garrido, NC Inestrosa
Journal of molecular biology 272 (3), 348-361, 1997
3761997
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
EM Toledo, NC Inestrosa
Molecular psychiatry 15 (3), 272-285, 2010
3582010
Platelets are the primary source of amyloid β-peptide in human blood
M Chen, NC Inestrosa, GS Ross, HL Fernandez
Biochemical and biophysical research communications 213 (1), 96-103, 1995
3561995
Wnt signaling in the nervous system and in Alzheimer's disease
NC Inestrosa, L Varela-Nallar
Journal of molecular cell biology 6 (1), 64-74, 2014
3492014
Amyloid–cholinesterase interactions: implications for Alzheimer’s disease
NC Inestrosa, MC Dinamarca, A Alvarez
The FEBS journal 275 (4), 625-632, 2008
3232008
Peroxisome proliferator-activated receptor γ up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative …
K Fuenzalida, R Quintanilla, P Ramos, D Piderit, RA Fuentealba, ...
Journal of Biological Chemistry 282 (51), 37006-37015, 2007
3192007
Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons
AR Alvarez, JA Godoy, K Mullendorff, GH Olivares, M Bronfman, ...
Experimental cell research 297 (1), 186-196, 2004
3102004
WNT signaling in neuronal maturation and synaptogenesis
SB Rosso, NC Inestrosa
Frontiers in cellular neuroscience 7, 103, 2013
2922013
Wnt signaling in neuroprotection and stem cell differentiation
EM Toledo, M Colombres, NC Inestrosa
Progress in neurobiology 86 (3), 281-296, 2008
2912008
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons
W Cerpa, JA Godoy, I Alfaro, GG Farías, MJ Metcalfe, R Fuentealba, ...
Journal of Biological Chemistry 283 (9), 5918-5927, 2008
2682008
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