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Ravi Amaravadi
Ravi Amaravadi
Dirección de correo verificada de uphs.upenn.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
12090*2021
Survival in BRAF V600–mutant advanced melanoma treated with vemurafenib
JA Sosman, KB Kim, L Schuchter, R Gonzalez, AC Pavlick, JS Weber, ...
New England Journal of Medicine 366 (8), 707-714, 2012
24192012
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ...
Nature 520 (7547), 373-377, 2015
20422015
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ...
The Journal of clinical investigation 117 (2), 326-336, 2007
13572007
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ...
Nature 545 (7652), 60-65, 2017
12392017
Autophagy in malignant transformation and cancer progression
L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ...
The EMBO journal 34 (7), 856-880, 2015
11052015
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
M Buzzai, RG Jones, RK Amaravadi, JJ Lum, RJ DeBerardinis, F Zhao, ...
Cancer research 67 (14), 6745-6752, 2007
10672007
Principles and current strategies for targeting autophagy for cancer treatment
RK Amaravadi, J Lippincott-Schwartz, XM Yin, WA Weiss, N Takebe, ...
Clinical cancer research 17 (4), 654-666, 2011
9582011
Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade
JL Benci, B Xu, Y Qiu, TJ Wu, H Dada, C Twyman-Saint Victor, L Cucolo, ...
Cell 167 (6), 1540-1554. e12, 2016
8442016
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ...
Nature 571 (7764), 211-218, 2019
7832019
Recent insights into the function of autophagy in cancer
R Amaravadi, AC Kimmelman, E White
Genes & development 30 (17), 1913-1930, 2016
6642016
The roles of therapy-induced autophagy and necrosis in cancer treatment
RK Amaravadi, CB Thompson
Clinical cancer research 13 (24), 7271-7279, 2007
5772007
Targeting Autophagy in Cancer: Recent Advances and Future DirectionsTargeting Autophagy in Cancer
RK Amaravadi, AC Kimmelman, J Debnath
Cancer discovery 9 (9), 1167-1181, 2019
5092019
The survival kinases Akt and Pim as potential pharmacological targets
R Amaravadi, CB Thompson
The Journal of clinical investigation 115 (10), 2618-2624, 2005
4922005
Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma
PA Ascierto, D Minor, A Ribas, C Lebbe, A O’Hagan, N Arya, M Guckert, ...
J Clin Oncol 31 (26), 3205-3211, 2013
4752013
Targeting autophagy in cancer
AV Onorati, M Dyczynski, R Ojha, RK Amaravadi
Cancer 124 (16), 3307-3318, 2018
4672018
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
MR Rosenfeld, X Ye, JG Supko, S Desideri, SA Grossman, S Brem, ...
Autophagy 10 (8), 1359-1368, 2014
4552014
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma
AC Huang, RJ Orlowski, X Xu, R Mick, SM George, PK Yan, S Manne, ...
Nature medicine 25 (3), 454-461, 2019
4372019
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma
K Trunzer, AC Pavlick, L Schuchter, R Gonzalez, GA McArthur, TE Hutson, ...
Journal of clinical oncology 31 (14), 1767-1774, 2013
4362013
Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ...
The Journal of clinical investigation 124 (3), 1406-1417, 2014
4062014
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Artículos 1–20