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Nicolas Picard, PharmD, PhD
Nicolas Picard, PharmD, PhD
Professor of Pharmacology, University of Limoges
Dirección de correo verificada de unilim.fr
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Is inappropriate medication use a major cause of adverse drug reactions in the elderly?
ML Laroche, JP Charmes, Y Nouaille, N Picard, L Merle
British journal of clinical pharmacology 63 (2), 177-186, 2007
4502007
Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism
N Picard, D Ratanasavanh, A Prémaud, Y Le Meur, P Marquet
Drug metabolism and disposition 33 (1), 139-146, 2005
3322005
The role of organic anion–transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics
N Picard, SW Yee, JB Woillard, Y Lebranchu, Y Le Meur, KM Giacomini, ...
Clinical Pharmacology & Therapeutics 87 (1), 100-108, 2010
1902010
In vitro metabolism study of buprenorphine: evidence for new metabolic pathways
N Picard, T Cresteil, N Djebli, P Marquet
Drug metabolism and disposition 33 (5), 689-695, 2005
1682005
Tacrolimus population pharmacokinetic-pharmacogenetic analysis and Bayesian estimation in renal transplant recipients
K Benkali, A Prémaud, N Picard, JP Rérolle, O Toupance, G Hoizey, ...
Clinical pharmacokinetics 48, 805-816, 2009
1612009
UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice
MC Etienne‐Grimaldi, JC Boyer, F Thomas, S Quaranta, N Picard, ...
Fundamental & Clinical Pharmacology 29 (3), 219-237, 2015
1162015
Contribution of the different UDP-glucuronosyltransferase (UGT) isoforms to buprenorphine and norbuprenorphine metabolism and relationship with the main UGT polymorphisms in a …
K Rouguieg, N Picard, FL Sauvage, JM Gaulier, P Marquet
Drug metabolism and disposition 38 (1), 40-45, 2010
1112010
Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5
N Picard, T Cresteil, A Prémaud, P Marquet
Therapeutic drug monitoring 26 (6), 600-608, 2004
942004
Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse
A Al Saabi, D Allorge, FL Sauvage, G Tournel, J Gaulier, P Marquet, ...
Drug Metabolism and Disposition 41 (3), 568-574, 2013
882013
Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients
N Djebli, N Picard, JP Rérolle, Y Le Meur, P Marquet
Pharmacogenetics and genomics 17 (5), 321-330, 2007
842007
Donor P‐gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long‐term follow‐up
JB Woillard, JP Rerolle, N Picard, A Rousseau, A Guillaudeau, ...
Clinical Pharmacology & Therapeutics 88 (1), 95-100, 2010
832010
Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil
O Gensburger, RHN Van Schaik, N Picard, Y Le Meur, A Rousseau, ...
Pharmacogenetics and genomics 20 (9), 537-543, 2010
772010
CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients
N Picard, K Rouguieg-Malki, N Kamar, L Rostaing, P Marquet
Transplantation 91 (6), 652-656, 2011
742011
Pharmacogenetic biomarkers predictive of the pharmacokinetics and pharmacodynamics of immunosuppressive drugs
N Picard, S Bergan, P Marquet, T Van Gelder, P Wallemacq, ...
Therapeutic drug monitoring 38, S57-S69, 2016
712016
A comparison of the effect of ciclosporin and sirolimus on the pharmokinetics of mycophenolate in renal transplant patients
N Picard, A Prémaud, A Rousseau, Y Le Meur, P Marquet
British journal of clinical pharmacology 62 (4), 477-484, 2006
692006
Risk of diarrhoea in a long‐term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8*2 variant allele
JB Woillard, JP Rerolle, N Picard, A Rousseau, M Drouet, E Munteanu, ...
British journal of clinical pharmacology 69 (6), 675-683, 2010
652010
General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints
FL Sauvage, N Picard, F Saint‐Marcoux, JM Gaulier, G Lachâtre, ...
Journal of separation science 32 (18), 3074-3083, 2009
562009
Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5
N Picard, N Djebli, FL Sauvage, P Marquet
Drug metabolism and disposition 35 (3), 350-355, 2007
562007
The influence of pharmacogenetics and cofactors on clinical outcomes in kidney transplantation
N Picard, P Marquet
Expert opinion on drug metabolism & toxicology 7 (6), 731-743, 2011
452011
Effect of CYP3A4*22, POR*28, and PPARA rs4253728 on Sirolimus In Vitro Metabolism and Trough Concentrations in Kidney Transplant Recipients
JB Woillard, N Kamar, S Coste, L Rostaing, P Marquet, N Picard
Clinical Chemistry 59 (12), 1761-1769, 2013
412013
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Artículos 1–20