| Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability DR Wise, PS Ward, JES Shay, JR Cross, JJ Gruber, UM Sachdeva, ... Proceedings of the National Academy of Sciences 108 (49), 19611-19616, 2011 | 1076 | 2011 |
| Ars2 regulates both miRNA-and siRNA-dependent silencing and suppresses RNA virus infection in Drosophila LR Sabin, R Zhou, JJ Gruber, N Lukinova, S Bambina, A Berman, CK Lau, ... Cell 138 (2), 340-351, 2009 | 241 | 2009 |
| Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation JJ Gruber, DS Zatechka, LR Sabin, J Yong, JJ Lum, M Kong, WX Zong, ... Cell 138 (2), 328-339, 2009 | 226 | 2009 |
| Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming F Zhao, A Mancuso, TV Bui, X Tong, JJ Gruber, CR Swider, PV Sanchez, ... Oncogene 29 (20), 2962-2972, 2010 | 196 | 2010 |
| Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility RS Stowers, A Shcherbina, J Israeli, JJ Gruber, J Chang, S Nam, ... Nature biomedical engineering 3 (12), 1009-1019, 2019 | 166 | 2019 |
| The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation X Tong, F Zhao, A Mancuso, JJ Gruber, CB Thompson Proceedings of the National Academy of Sciences 106 (51), 21660-21665, 2009 | 165 | 2009 |
| DR5 knockout mice are compromised in radiation-induced apoptosis N Finnberg, JJ Gruber, P Fei, D Rudolph, A Bric, SH Kim, TF Burns, ... Molecular and cellular biology 25 (5), 2000-2013, 2005 | 140 | 2005 |
| Long-lived microRNA–Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses SH Olejniczak, G La Rocca, JJ Gruber, CB Thompson Proceedings of the National Academy of Sciences 110 (1), 157-162, 2013 | 89 | 2013 |
| Ars2 promotes proper replication-dependent histone mRNA 3′ end formation JJ Gruber, SH Olejniczak, J Yong, G La Rocca, G Dreyfuss, CB Thompson Molecular cell 45 (1), 87-98, 2012 | 88 | 2012 |
| Differentiated thyroid cancer: focus on emerging treatments for radioactive iodine-refractory patients JJ Gruber, AD Colevas The oncologist 20 (2), 113-126, 2015 | 78 | 2015 |
| Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription TP Cash, JJ Gruber, TR Hartman, EP Henske, MC Simon Oncogene 30 (22), 2534-2546, 2011 | 72 | 2011 |
| HAT1 coordinates histone production and acetylation via H4 promoter binding JJ Gruber, B Geller, AM Lipchik, J Chen, AA Salahudeen, AN Ram, ... Molecular cell 75 (4), 711-724. e5, 2019 | 58 | 2019 |
| The PP2A-associated protein α4 plays a critical role in the regulation of cell spreading and migration M Kong, TV Bui, D Ditsworth, JJ Gruber, D Goncharov, VP Krymskaya, ... Journal of biological chemistry 282 (40), 29712-29720, 2007 | 53 | 2007 |
| Talazoparib beyond BRCA: A phase II trial of talazoparib monotherapy in BRCA1 and BRCA2 wild-type patients with advanced HER2-negative breast cancer or … JJ Gruber, A Afghahi, A Hatton, D Scott, A McMillan, JM Ford, ML Telli Journal of Clinical Oncology 37 (15_suppl), 3006-3006, 2019 | 49 | 2019 |
| Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia Y Li, JJ Gruber, UM Litzenburger, Y Zhou, YR Miao, EL LaGory, AM Li, ... Cell Death & Disease 11 (2), 102, 2020 | 46 | 2020 |
| A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes JJ Gruber, A Afghahi, K Timms, A DeWees, W Gross, VN Aushev, HT Wu, ... Nature Cancer 3 (10), 1181-1191, 2022 | 45 | 2022 |
| Rationally targeted anti-VISTA antibody that blockades the C-C’loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit … D Thakkar, S Paliwal, B Dharmadhikari, S Guan, L Liu, S Kar, NK Tulsian, ... Journal for Immunotherapy of Cancer 10 (2), 2022 | 28 | 2022 |
| Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid Q Liu, K Van Bortle, Y Zhang, MT Zhao, JZ Zhang, BS Geller, JJ Gruber, ... Scientific reports 8 (1), 12960, 2018 | 26 | 2018 |
| Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast … ML Telli, C Chu, SS Badve, S Vinayak, DP Silver, SJ Isakoff, V Kaklamani, ... Clinical Cancer Research 26 (11), 2704-2710, 2020 | 24 | 2020 |
| Chromatin accessibility associates with protein-RNA correlation in human cancer A Sanghi, JJ Gruber, A Metwally, L Jiang, W Reynolds, J Sunwoo, L Orloff, ... Nature communications 12 (1), 5732, 2021 | 19 | 2021 |
