Chun Wei Yap
Chun Wei Yap
National Healthcare Group
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PaDEL‐descriptor: An open source software to calculate molecular descriptors and fingerprints
CW Yap
Journal of computational chemistry 32 (7), 1466-1474, 2011
Social isolation, loneliness and their relationships with depressive symptoms: A population-based study
L Ge, CW Yap, R Ong, BH Heng
PloS one 12 (8), e0182145, 2017
Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway
CC Woo, SY Loo, V Gee, CW Yap, G Sethi, AP Kumar, KHB Tan
Biochemical pharmacology 82 (5), 464-475, 2011
Prediction of P-glycoprotein substrates by a support vector machine approach
Y Xue, CW Yap, LZ Sun, ZW Cao, JF Wang, YZ Chen
Journal of chemical information and computer sciences 44 (4), 1497-1505, 2004
Therapeutic targets: progress of their exploration and investigation of their characteristics
CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao, YZ Chen
Pharmacological reviews 58 (2), 259-279, 2006
Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents
Y Xue, ZR Li, CW Yap, LZ Sun, X Chen, YZ Chen
Journal of chemical information and computer sciences 44 (5), 1630-1638, 2004
Prediction of cytochrome P450 3A4, 2D6, and 2C9 inhibitors and substrates by using support vector machines
CW Yap, YZ Chen
Journal of chemical information and modeling 45 (4), 982-992, 2005
QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo‐) triazoles on Algae
P Gramatica, S Cassani, PP Roy, S Kovarich, CW Yap, E Papa
Molecular Informatics 31 (11‐12), 817-835, 2012
Effect of selection of molecular descriptors on the prediction of blood-brain barrier penetrating and nonpenetrating agents by statistical learning methods
H Li, CW Yap, CY Ung, Y Xue, ZW Cao, YZ Chen
Journal of chemical information and modeling 45 (5), 1376-1384, 2005
Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer
L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ...
Journal of Biological Chemistry 287 (45), 38028-38040, 2012
Formulation development of transdermal dosage forms: Quantitative structure-activity relationship model for predicting activities of terpenes that enhance drug penetration …
L Kang, CW Yap, PFC Lim, YZ Chen, PC Ho, YW Chan, GP Wong, ...
Journal of controlled release 120 (3), 211-219, 2007
Prediction of genotoxicity of chemical compounds by statistical learning methods
H Li, CY Ung, CW Yap, Y Xue, ZR Li, ZW Cao, YZ Chen
Chemical research in toxicology 18 (6), 1071-1080, 2005
Prediction of torsade-causing potential of drugs by support vector machine approach
CW Yap, CZ Cai, Y Xue, YZ Chen
Toxicological Sciences 79 (1), 170-177, 2004
Mixed learning algorithms and features ensemble in hepatotoxicity prediction
CY Liew, YC Lim, CW Yap
Journal of computer-aided molecular design 25 (9), 855-871, 2011
Classification of a diverse set of tetrahymena pyriformis toxicity chemical compounds from molecular descriptors by statistical learning methods
Y Xue, H Li, CY Ung, CW Yap, YZ Chen
Chemical research in toxicology 19 (8), 1030-1039, 2006
Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity
FF Gan, KK Kaminska, H Yang, CY Liew, PC Leow, CL So, LL Tu Ngoc, ...
Antioxidants & Redox Signaling, 2013
Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins
H Li, CW Yap, CY Ung, Y Xue, ZR Li, LY Han, HH Lin, YZ Chen
Journal of pharmaceutical sciences 96 (11), 2838-2860, 2007
In Silico Prediction of Pregnane X Receptor Activators by Machine Learning Approache
CY Ung, H Li, CW Yap, YZ Chen
Molecular pharmacology 71 (1), 158-168, 2007
Progress and problems in the exploration of therapeutic targets
C Zheng, L Han, CW Yap, B Xie, Y Chen
Drug discovery today 11 (9), 412-420, 2006
Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods
CW Yap, ZR Li, YZ Chen
Journal of Molecular Graphics and Modelling 24 (5), 383-395, 2006
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