David R. Liu
David R. Liu
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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ...
Science 324 (5929), 930-935, 2009
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
AC Komor, YB Kim, MS Packer, JA Zuris, DR Liu
Nature 533 (7603), 420-424, 2016
Programmable base editing of A• T to G• C in genomic DNA without DNA cleavage
NM Gaudelli, AC Komor, HA Rees, MS Packer, AH Badran, DI Bryson, ...
Nature 551 (7681), 464-471, 2017
Search-and-replace genome editing without double-strand breaks or donor DNA
AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ...
Nature 576 (7785), 149-157, 2019
Scaling of theory‐of‐mind tasks
HM Wellman, D Liu
Child development 75 (2), 523-541, 2004
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
DW Huang, BT Sherman, Q Tan, J Kir, D Liu, D Bryant, Y Guo, ...
Nucleic acids research 35 (suppl_2), W169-W175, 2007
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu
Nature biotechnology 31 (9), 839-843, 2013
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a …
ED Kwon, CG Drake, HI Scher, K Fizazi, A Bossi, AJM Van den Eertwegh, ...
The lancet oncology 15 (7), 700-712, 2014
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
JA Zuris, DB Thompson, Y Shu, JP Guilinger, JL Bessen, JH Hu, ...
Nature biotechnology 33 (1), 73-80, 2015
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
JH Hu, SM Miller, MH Geurts, W Tang, L Chen, N Sun, CM Zeina, X Gao, ...
Nature 556 (7699), 57-63, 2018
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
AV Anzalone, LW Koblan, DR Liu
Nature biotechnology 38 (7), 824-844, 2020
Base editing: precision chemistry on the genome and transcriptome of living cells
HA Rees, DR Liu
Nature reviews genetics 19 (12), 770-788, 2018
Sequence-controlled polymers
JF Lutz, M Ouchi, DR Liu, M Sawamoto
Science 341 (6146), 1238149, 2013
CRISPR-based technologies for the manipulation of eukaryotic genomes
AC Komor, AH Badran, DR Liu
Cell 168 (1), 20-36, 2017
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
JP Guilinger, DB Thompson, DR Liu
Nature biotechnology 32 (6), 577-582, 2014
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
Methods for the directed evolution of proteins
MS Packer, DR Liu
Nature Reviews Genetics 16 (7), 379-394, 2015
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing
Y Huang, WA Pastor, Y Shen, M Tahiliani, DR Liu, A Rao
PloS one 5 (1), e8888, 2010
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