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Matthew Porteus
Matthew Porteus
Professor of Pediatrics, Stanford University
Dirección de correo verificada de stanford.edu
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Highly efficient endogenous human gene correction using designed zinc-finger nucleases
FD Urnov, JC Miller, YL Lee, CM Beausejour, JM Rock, S Augustus, ...
Nature 435 (7042), 646-651, 2005
21802005
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
A Hendel, RO Bak, JT Clark, AB Kennedy, DE Ryan, S Roy, I Steinfeld, ...
Nature biotechnology 33 (9), 985-989, 2015
11722015
Chimeric nucleases stimulate gene targeting in human cells
MH Porteus, D Baltimore
Science 300 (5620), 763-763, 2003
11232003
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science 351 (6280), 1454-1458, 2016
10382016
Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification
ML Maeder, S Thibodeau-Beganny, A Osiak, DA Wright, RM Anthony, ...
Molecular cell 31 (2), 294-301, 2008
9642008
Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ...
Nature medicine 25 (2), 249-254, 2019
9322019
Gene targeting using zinc finger nucleases
MH Porteus, D Carroll
Nature biotechnology 23 (8), 967-973, 2005
9262005
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
DP Dever, RO Bak, A Reinisch, J Camarena, G Washington, CE Nicolas, ...
Nature 539 (7629), 384-389, 2016
9082016
Transplantation outcomes for severe combined immunodeficiency, 2000–2009
SY Pai, BR Logan, LM Griffith, RH Buckley, RE Parrott, CC Dvorak, ...
New England Journal of Medicine 371 (5), 434-446, 2014
7432014
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ...
Nature medicine 24 (8), 1216-1224, 2018
7322018
Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States
A Kwan, RS Abraham, R Currier, A Brower, K Andruszewski, JK Abbott, ...
Jama 312 (7), 729-738, 2014
7232014
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells
S Durai, M Mani, K Kandavelou, J Wu, MH Porteus, S Chandrasegaran
Nucleic acids research 33 (18), 5978-5990, 2005
6902005
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ...
Science 342 (6155), 253-257, 2013
6672013
Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental …
A Bulfone, L Puelles, MH Porteus, MA Frohman, GR Martin, ...
Journal of Neuroscience 13 (7), 3155-3172, 1993
6561993
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
J Zou, ML Maeder, P Mali, SM Pruett-Miller, S Thibodeau-Beganny, ...
Cell stem cell 5 (1), 97-110, 2009
6232009
Use of chimeric nucleases to stimulate gene targeting
D Baltimore, M Porteus
US Patent 9,447,434, 2016
4512016
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
GG Sharma, S So, A Gupta, R Kumar, C Cayrou, N Avvakumov, U Bhadra, ...
Molecular and cellular biology 30 (14), 3582-3595, 2010
3542010
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double‐strand breaks
PR Potts, MH Porteus, H Yu
The EMBO journal 25 (14), 3377-3388, 2006
3212006
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis
N Gomez-Ospina, CJ Potter, R Xiao, K Manickam, MS Kim, KH Kim, ...
Nature communications 7 (1), 10713, 2016
2942016
CRISPR/Cas9 genome editing in human hematopoietic stem cells
RO Bak, DP Dever, MH Porteus
Nature protocols 13 (2), 358-376, 2018
2852018
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Artículos 1–20