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Hyuk-Soo Seo
Hyuk-Soo Seo
Dana-Farber Cancer Institute
Dirección de correo verificada de crystal.harvard.edu
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Transcription control by the ENL YEATS domain in acute leukaemia
MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ...
Nature 543 (7644), 270-274, 2017
3012017
Degradation of the BAF complex factor BRD9 by heterobifunctional ligands
D Remillard, DL Buckley, J Paulk, GL Brien, M Sonnett, HS Seo, ...
Angewandte Chemie International Edition 56 (21), 5738-5743, 2017
2922017
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands
LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ...
Nature chemical biology 14 (4), 405-412, 2018
2142018
Structure-guided development of a potent and selective non-covalent active-site inhibitor of USP7
I Lamberto, X Liu, HS Seo, NJ Schauer, RE Iacob, W Hu, D Das, ...
Cell chemical biology 24 (12), 1490-1500. e11, 2017
1602017
Design and characterization of bivalent BET inhibitors
M Tanaka, JM Roberts, HS Seo, A Souza, J Paulk, TG Scott, SL DeAngelo, ...
Nature chemical biology 12 (12), 1089-1096, 2016
1412016
A fence-like coat for the nuclear pore membrane
EW Debler, Y Ma, HS Seo, KC Hsia, TR Noriega, G Blobel, A Hoelz
Molecular cell 32 (6), 815-826, 2008
1402008
Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells
S Kozono, YM Lin, HS Seo, B Pinch, X Lian, C Qiu, MK Herbert, CH Chen, ...
Nature communications 9 (1), 3069, 2018
1372018
Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1
Y Ren, HS Seo, G Blobel, A Hoelz
Proceedings of the National Academy of Sciences 107 (23), 10406-10411, 2010
1192010
Inhibition of USP10 induces degradation of oncogenic FLT3
EL Weisberg, NJ Schauer, J Yang, I Lamberto, L Doherty, S Bhatt, ...
Nature chemical biology 13 (12), 1207-1215, 2017
1132017
MELK is not necessary for the proliferation of basal-like breast cancer cells
HT Huang, HS Seo, T Zhang, Y Wang, B Jiang, Q Li, DL Buckley, B Nabet, ...
Elife 6, e26693, 2017
1042017
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo
C Dubiella, BJ Pinch, K Koikawa, D Zaidman, E Poon, TD Manz, B Nabet, ...
Nature chemical biology 17 (9), 954-963, 2021
932021
EF-G-dependent GTPase on the ribosome. Conformational change and fusidic acid inhibition
HS Seo, S Abedin, D Kamp, DN Wilson, KH Nierhaus, BS Cooperman
Biochemistry 45 (8), 2504-2514, 2006
922006
Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex
HS Seo, Y Ma, EW Debler, D Wacker, S Kutik, G Blobel, A Hoelz
Proceedings of the National Academy of Sciences 106 (34), 14281-14286, 2009
882009
Recurrent SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF complex chromatin remodeling
AM Valencia, CK Collings, HT Dao, RS Pierre, YC Cheng, J Huang, ...
Cell 179 (6), 1342-1356. e23, 2019
852019
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1• Nup98)
B Quan, HS Seo, G Blobel, Y Ren
Proceedings of the National Academy of Sciences 111 (25), 9127-9132, 2014
742014
Structural and functional consequences of the STAT5BN642H driver mutation
ED de Araujo, F Erdogan, HA Neubauer, D Meneksedag-Erol, ...
Nature communications 10 (1), 2517, 2019
722019
An aluminum hydroxide: CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice
E Nanishi, F Borriello, TR O’Meara, ME McGrath, Y Saito, RE Haupt, ...
Science translational medicine 14 (629), eabj5305, 2021
702021
Lactate regulates cell cycle by remodelling the anaphase promoting complex
W Liu, Y Wang, LHM Bozi, PD Fischer, MP Jedrychowski, H Xiao, T Wu, ...
Nature 616 (7958), 790-797, 2023
582023
Identification of a potent and selective covalent Pin1 inhibitor
BJ Pinch, ZM Doctor, B Nabet, CM Browne, HS Seo, ML Mohardt, ...
Nature chemical biology 16 (9), 979-987, 2020
582020
Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex
K Yoshida, HS Seo, EW Debler, G Blobel, A Hoelz
Proceedings of the National Academy of Sciences 108 (40), 16571-16576, 2011
582011
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