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Maxime Louet
Maxime Louet
Dirección de correo verificada de umontpellier.fr
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Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
S Mary, M Damian, M Louet, N Floquet, JA Fehrentz, J Marie, J Martinez, ...
Proceedings of the National Academy of Sciences 109 (21), 8304-8309, 2012
1182012
Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains
L Charlier, M Louet, L Chaloin, P Fuchs, J Martinez, D Muriaux, C Favard, ...
Biophysical journal 106 (3), 577-585, 2014
772014
Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism
A Isvoran, M Louet, DL Vladoiu, D Craciun, MA Loriot, BO Villoutreix, ...
Drug Discovery Today 22 (2), 366-376, 2017
752017
GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation
M Damian, V Pons, P Renault, C M’kadmi, B Delort, L Hartmann, AI Kaya, ...
Proceedings of the National Academy of Sciences 115 (17), 4501-4506, 2018
652018
Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain
G Ferré, M Louet, O Saurel, B Delort, G Czaplicki, C M’kadmi, M Damian, ...
Proceedings of the National Academy of Sciences 116 (35), 17525-17530, 2019
582019
A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins
M Louet, D Perahia, J Martinez, N Floquet
Journal of molecular biology 411 (1), 298-312, 2011
362011
Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9* 30
M Louet, CM Labbé, C Fagnen, CM Aono, P Homem-de-Mello, ...
PLoS One 13 (5), e0197249, 2018
352018
Allosteric modulation of ghrelin receptor signaling by lipids
M Damian, M Louet, AAS Gomes, C M’kadmi, S Denoyelle, S Cantel, ...
Nature communications 12 (1), 3938, 2021
332021
Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
J Bous, H Orcel, N Floquet, C Leyrat, J Lai-Kee-Him, G Gaibelet, ...
Science Advances 7 (21), eabg5628, 2021
302021
GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins
M Louet, J Martinez, N Floquet
PLoS computational biology 8 (7), e1002595, 2012
262012
Dynamic allostery of the catabolite activator protein revealed by interatomic forces
M Louet, C Seifert, U Hensen, F Gräter
PLoS computational biology 11 (8), e1004358, 2015
222015
Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2a Receptor by a Mini-G Protein
P Renault, M Louet, J Marie, G Labesse, N Floquet
Scientific reports 9 (1), 5495, 2019
192019
In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
M Louet, S Bitam, N Bakouh, Y Bignon, G Planelles, D Lagorce, ...
Scientific reports 7 (1), 7249, 2017
142017
Conformational restriction of G-proteins Coupled Receptors (GPCRs) upon complexation to G-proteins: A putative activation mode of GPCRs?
M Louet, E Karakas, A Perret, D Perahia, J Martinez, N Floquet
FEBS letters 587 (16), 2656-2661, 2013
122013
Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
M Louet, M Casiraghi, M Damian, MGS Costa, P Renault, AAS Gomes, ...
Elife 10, e63201, 2021
62021
Dissociation of Membrane-Anchored Heterotrimeric G-Protein Induced by Gα Subunit Binding to GTP
M Louet, L Charlier, J Martinez, N Floquet
Journal of chemical information and modeling 52 (11), 3022-3027, 2012
42012
Sodium is a negative allosteric regulator of the ghrelin receptor
G Ferré, AAS Gomes, M Louet, M Damian, PM Bisch, O Saurel, N Floquet, ...
Cell Reports 42 (4), 2023
32023
MDexciteR: enhanced sampling molecular dynamics by excited normal modes or principal components obtained from experiments
MGS Costa, PR Batista, A Gomes, LS Bastos, M Louet, N Floquet, ...
Journal of Chemical Theory and Computation 19 (2), 412-425, 2023
22023
Identification of First-in-class inhibitors of Kallikrein-Related peptidase 6 that promote oligodendrocyte differentiation
S Aït Amiri, C Deboux, F Soualmia, N Chaaya, M Louet, E Duplus, ...
Journal of Medicinal Chemistry 64 (9), 5667-5688, 2021
12021
LIPIDS MODULATE THE DYNAMICS OF GPCR: β-ARRESTIN INTERACTION
G AAS, M DI MICHELE, R RA, M DAMIAN, B PM, N SIBILLE, M LOUET, ...
2024
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