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Christian R Schubert
Christian R Schubert
MIT | Harvard | Pfizer | Biogen | Servier | Atlas Venture | AbbVie
Dirección de correo verificada de alum.mit.edu
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Biological insights from 108 schizophrenia-associated genetic loci
C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ...
Nature 511 (7510), 421-427, 2014
73942014
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
B Bulik-Sullivan, PR Loh, H Finucane, S Ripke, J Yang, N Patterson, ...
Nature Genetics 47 (3), 291-5, 2015
43022015
An atlas of genetic correlations across human diseases and traits
B Bulik-Sullivan, HK Finucane, V Anttila, A Gusev, FR Day, PR Loh, ...
Nature genetics 47 (11), 1236-1241, 2015
34102015
Schizophrenia risk from complex variation of complement component 4
A Sekar, AR Bialas, H De Rivera, A Davis, TR Hammond, N Kamitaki, ...
Nature 530 (7589), 177-183, 2016
23412016
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228-1235, 2015
21722015
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
13282015
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
12282022
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
6492014
Comparative genetic architectures of schizophrenia in East Asian and European populations
M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma, H Gaspar, M Ikeda, ...
Nature genetics 51 (12), 1670-1678, 2019
5172019
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
5082018
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
PR Loh, G Bhatia, A Gusev, HK Finucane, BK Bulik-Sullivan, SJ Pollack, ...
Nature Genetics doi: 10.1038/ng.3431, 2015
4912015
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ...
Nature genetics 50 (4), 538-548, 2018
4272018
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
DM Ruderfer, AH Fanous, S Ripke, A McQuillin, RL Amdur, PV Gejman, ...
Molecular psychiatry 19 (9), 1017-1024, 2014
3722014
Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia
Schizophrenia Working Group of the Psychiatric Genomics Consortium, ...
MedRxiv, 2020.09. 12.20192922, 2020
3162020
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
AE Jaffe, RE Straub, JH Shin, R Tao, Y Gao, L Collado-Torres, ...
Nature neuroscience 21 (8), 1117-1125, 2018
3112018
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
B Franke, JL Stein, S Ripke, V Anttila, DP Hibar, KJE Van Hulzen, ...
Nature neuroscience 19 (3), 420-431, 2016
2382016
Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism
MH Chahrour, TW Yu, ET Lim, B Ataman, ME Coulter, RS Hill, ...
PLoS genetics 8 (4), e1002635, 2012
2282012
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
N Mullins, TB Bigdeli, AD Børglum, JRI Coleman, D Demontis, D Mehta, ...
American journal of psychiatry 176 (8), 651-660, 2019
2202019
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
SH Witt, F Streit, M Jungkunz, J Frank, S Awasthi, CS Reinbold, ...
Translational psychiatry 7 (6), e1155-e1155, 2017
1862017
Complement genes contribute sex-biased vulnerability in diverse disorders
N Kamitaki, A Sekar, RE Handsaker, H De Rivera, K Tooley, DL Morris, ...
Nature 582 (7813), 577-581, 2020
1802020
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20