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James Hadfield
James Hadfield
Director Epigenomics, Tranlsational Medicine TDE, Astrazeneca, UK
Dirección de correo verificada de CRUK.cam.ac.uk - Página principal
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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
61912012
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
M Murtaza, SJ Dawson, DWY Tsui, D Gale, T Forshew, AM Piskorz, ...
Nature 497 (7447), 108-112, 2013
19462013
RNA sequencing: the teenage years
R Stark, M Grzelak, J Hadfield
Nature Reviews Genetics 20 (11), 631-656, 2019
17962019
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA
T Forshew, M Murtaza, C Parkinson, D Gale, DWY Tsui, F Kaper, ...
Science Translational Medicine 4 (136), 136ra68-136ra68, 2012
15782012
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
Nature biotechnology 32 (9), 903-914, 2014
8682014
Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression
A Git, H Dvinge, M Salmon-Divon, M Osborne, C Kutter, J Hadfield, ...
Rna 16 (5), 991-1006, 2010
8102010
Progesterone receptor modulates ER [agr] action in breast cancer
H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ...
Nature 523 (7560), 313-317, 2015
7742015
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
CE Massie, A Lynch, A Ramos-Montoya, J Boren, R Stark, L Fazli, ...
The EMBO Journal 30 (13), 2719-2733, 2011
7082011
ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions
D Schmidt, MD Wilson, C Spyrou, GD Brown, J Hadfield, DT Odom
Methods 48 (3), 240-248, 2009
6282009
A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning
RM Mitra, CA Gleason, A Edwards, J Hadfield, JA Downie, GED Oldroyd, ...
Science Signalling 101 (13), 4701, 2004
5882004
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension
EAB Azizan, H Poulsen, P Tuluc, J Zhou, MV Clausen, A Lieb, C Maniero, ...
Nature genetics 45 (9), 1055-1060, 2013
5442013
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
PP Das, MP Bagijn, LD Goldstein, JR Woolford, NJ Lehrbach, ...
Molecular cell 31 (1), 79-90, 2008
4962008
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
4662016
Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
K Bach, S Pensa, M Grzelak, J Hadfield, DJ Adams, JC Marioni, ...
Nature communications 8 (1), 1-11, 2017
2932017
The pitfalls of platform comparison: DNA copy number array technologies assessed
C Curtis, AG Lynch, MJ Dunning, I Spiteri, JC Marioni, J Hadfield, SF Chin, ...
BMC genomics 10, 1-23, 2009
1242009
Additional targets of the Arabidopsis autonomous pathway members, FCA and FY
S Marquardt, PK Boss, J Hadfield, C Dean
Journal of experimental botany 57 (13), 3379-3386, 2006
912006
STS markers for the wheat yellow rust resistance gene Yr5 suggest a NBS–LRR-type resistance gene cluster
PH Smith, J Hadfield, NJ Hart, RMD Koebner, LA Boyd
Genome 50 (3), 259-265, 2007
682007
Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells
KA Holmes, A Hurtado, GD Brown, R Launchbury, CS Ross-Innes, ...
Proceedings of the National Academy of Sciences 109 (8), 2748-2753, 2012
572012
Introduction to miRNA profiling technologies and cross-platform comparison.
S Aldridge, J Hadfield
Methods in molecular biology (Clifton, NJ) 822, 19, 2012
512012
Multi-genome alignment for quality control and contamination screening of next-generation sequencing data.
J Hadfield, MD Eldridge
Name: Frontiers in Genetics 5, 31, 2014
352014
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Artículos 1–20