James Hadfield
James Hadfield
Director Epigenomics, Tranlsational Medicine TDE, Astrazeneca, UK
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Citado por
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
M Murtaza, SJ Dawson, DWY Tsui, D Gale, T Forshew, AM Piskorz, ...
Nature 497 (7447), 108-112, 2013
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA
T Forshew, M Murtaza, C Parkinson, D Gale, DWY Tsui, F Kaper, ...
Science Translational Medicine 4 (136), 136ra68-136ra68, 2012
RNA sequencing: the teenage years
R Stark, M Grzelak, J Hadfield
Nature Reviews Genetics 20 (11), 631-656, 2019
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
SEQC Consortium
Nature biotechnology 32 (9), 903, 2014
Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression
A Git, H Dvinge, M Salmon-Divon, M Osborne, C Kutter, J Hadfield, ...
Rna 16 (5), 991-1006, 2010
Progesterone receptor modulates ER [agr] action in breast cancer
H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ...
Nature 523 (7560), 313-317, 2015
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
CE Massie, A Lynch, A Ramos-Montoya, J Boren, R Stark, L Fazli, ...
The EMBO Journal 30 (13), 2719-2733, 2011
ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions
D Schmidt, MD Wilson, C Spyrou, GD Brown, J Hadfield, DT Odom
Methods 48 (3), 240-248, 2009
A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning
RM Mitra, CA Gleason, A Edwards, J Hadfield, JA Downie, GED Oldroyd, ...
Science Signalling 101 (13), 4701, 2004
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension
EAB Azizan, H Poulsen, P Tuluc, J Zhou, MV Clausen, A Lieb, C Maniero, ...
Nature genetics 45 (9), 1055-1060, 2013
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
PP Das, MP Bagijn, LD Goldstein, JR Woolford, NJ Lehrbach, ...
Molecular cell 31 (1), 79-90, 2008
A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds
A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ...
Cell 167 (1), 260-274. e22, 2016
Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
K Bach, S Pensa, M Grzelak, J Hadfield, DJ Adams, JC Marioni, ...
Nature communications 8 (1), 1-11, 2017
The pitfalls of platform comparison: DNA copy number array technologies assessed
C Curtis, AG Lynch, MJ Dunning, I Spiteri, JC Marioni, J Hadfield, SF Chin, ...
BMC genomics 10 (1), 1-23, 2009
Additional targets of the Arabidopsis autonomous pathway members, FCA and FY
S Marquardt, PK Boss, J Hadfield, C Dean
Journal of experimental botany 57 (13), 3379-3386, 2006
STS markers for the wheat yellow rust resistance gene Yr5 suggest a NBS–LRR-type resistance gene cluster
PH Smith, J Hadfield, NJ Hart, RMD Koebner, LA Boyd
Genome 50 (3), 259-265, 2007
Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells
KA Holmes, A Hurtado, GD Brown, R Launchbury, CS Ross-Innes, ...
Proceedings of the National Academy of Sciences 109 (8), 2748-2753, 2012
Introduction to miRNA profiling technologies and cross-platform comparison.
S Aldridge, J Hadfield
Methods in molecular biology (Clifton, NJ) 822, 19, 2012
The role of high-throughput technologies in clinical cancer genomics
SF Idris, SS Ahmad, MA Scott, GS Vassiliou, J Hadfield
Expert Review of Molecular Diagnostics 13 (2), 167-181, 2013
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Artículos 1–20