Seguir
Donald M. O'Rourke
Título
Citado por
Citado por
Año
IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
18342012
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...
Science translational medicine 9 (399), eaaa0984, 2017
10222017
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial
M Weller, N Butowski, DD Tran, LD Recht, M Lim, H Hirte, L Ashby, ...
The Lancet Oncology 18 (10), 1373-1385, 2017
6622017
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity
F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...
Cell 180 (1), 188-204. e22, 2020
3372020
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving …
A Maity, N Pore, J Lee, D Solomon, DM O’Rourke
Cancer research 60 (20), 5879-5886, 2000
3262000
Induction of ischemic tolerance following brief focal ischemia in rat brain
SS Glazier, DM O'Rourke, DI Graham, FA Welsh
Journal of Cerebral Blood Flow & Metabolism 14 (4), 545-553, 1994
2861994
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1–independent mechanism
N Pore, S Liu, HK Shu, B Li, D Haas-Kogan, D Stokoe, J Milanini-Mongiat, ...
Molecular biology of the cell 15 (11), 4841-4853, 2004
2762004
Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo
BW Park, HT Zhang, C Wu, A Berezov, X Zhang, R Dua, Q Wang, G Kao, ...
Nature biotechnology 18 (2), 194-198, 2000
2532000
Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques
L Macyszyn, H Akbari, JM Pisapia, X Da, M Attiah, V Pigrish, Y Bi, S Pal, ...
Neuro-oncology 18 (3), 417-425, 2015
2412015
Intraaxial Brain Masses: MR Imaging–based Diagnostic Strategy—Initial Experience1
RN Al-Okaili, J Krejza, JH Woo, RL Wolf, DM O'Rourke, KD Judy, ...
Radiology 243 (2), 539-550, 2007
2162007
PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating …
N Pore, S Liu, DA Haas-Kogan, DM O’Rourke, A Maity
Cancer research 63 (1), 236-241, 2003
2032003
Grading of CNS neoplasms using continuous arterial spin labeled perfusion MR imaging at 3 Tesla
RL Wolf, J Wang, S Wang, ER Melhem, DM O'Rourke, KD Judy, JA Detre
Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2005
1962005
Differentiation between glioblastomas, solitary brain metastases, and primary cerebral lymphomas using diffusion tensor and dynamic susceptibility contrast-enhanced MR imaging
S Wang, S Kim, S Chawla, RL Wolf, DE Knipp, A Vossough, DM O'Rourke, ...
American Journal of Neuroradiology 32 (3), 507-514, 2011
1792011
Differentiation between glioblastomas and solitary brain metastases using diffusion tensor imaging
S Wang, S Kim, S Chawla, RL Wolf, WG Zhang, DM O'Rourke, KD Judy, ...
Neuroimage 44 (3), 653-660, 2009
1692009
The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors
CJ Wu, DM O'Rourke, GS Feng, GR Johnson, Q Wang, MI Greene
Oncogene 20 (42), 6018-6025, 2001
1662001
Constitutive EGFR signaling confers a motile phenotype to neural stem cells
JA Boockvar, D Kapitonov, G Kapoor, J Schouten, GJ Counelis, O Bogler, ...
Molecular and Cellular Neuroscience 24 (4), 1116-1130, 2003
1482003
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells
A Ayuso-Sacido, JA Moliterno, S Kratovac, GS Kapoor, DM O’Rourke, ...
Journal of neuro-oncology 97 (3), 323-337, 2010
1442010
CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges
SJ Bagley, AS Desai, GP Linette, CH June, DM O’Rourke
Neuro-oncology 20 (11), 1429-1438, 2018
1432018
Expression of oncogenic epidermal growth factor receptor family kinases induces paclitaxel resistance and alters β-tubulin isotype expression
RB Montgomery, J Guzman, DM O'Rourke, WL Stahl
Journal of Biological chemistry 275 (23), 17358-17363, 2000
1352000
Compositions and methods of treating tumors
MI Greene, DM O'rourke, R Murali, BW Park
US Patent 6,417,168, 2002
131*2002
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20