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Xiaofeng Cai, M.D., Ph.D.
Xiaofeng Cai, M.D., Ph.D.
Dirección de correo verificada de omrf.org
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Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling
S Pasula, X Cai, Y Dong, M Messa, J McManus, B Chang, X Liu, H Zhu, ...
The Journal of clinical investigation 122 (12), 4424-4438, 2012
1212012
Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function
X Liu, S Pasula, H Song, KL Tessneer, Y Dong, S Hahn, T Yago, ...
Science signaling 7 (347), ra97-ra97, 2014
632014
Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets
Y Pan, T Yago, J Fu, B Herzog, JM McDaniel, P Mehta-D’Souza, X Cai, ...
Blood, The Journal of the American Society of Hematology 124 (24), 3656-3665, 2014
552014
Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes
H Wu, HNA Rahman, Y Dong, X Liu, Y Lee, A Wen, KHT To, L Xiao, ...
The Journal of Clinical Investigation 128 (9), 4025-4043, 2018
532018
Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency
KL Tessneer, S Pasula, X Cai, Y Dong, J McManus, X Liu, L Yu, S Hahn, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (2), 331-337, 2014
502014
Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein
J Hu, XF Cai, G Yan
Cell cycle 8 (20), 3328-3339, 2009
482009
Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells
H Giri, SR Panicker, X Cai, I Biswas, H Weiler, AR Rezaie
Proc Natl Acad Sci U S A. 118 (11), e2022248118, 2021
472021
Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development
B Chang, KL Tessneer, J McManus, X Liu, S Hahn, S Pasula, H Wu, ...
Nature communications 6 (1), 6380, 2015
462015
Selective targeting of a novel epsin–VEGFR2 interaction promotes VEGF-mediated angiogenesis
HNA Rahman, H Wu, Y Dong, S Pasula, A Wen, Y Sun, ML Brophy, ...
Circulation research 118 (6), 957-969, 2016
432016
Motif mimetic of epsin perturbs tumor growth and metastasis
Y Dong, H Wu, HNA Rahman, Y Liu, S Pasula, KL Tessneer, X Cai, X Liu, ...
The Journal of clinical investigation 125 (12), 4349-4364, 2015
332015
Loss of core 1-derived O-glycans decreases breast cancer development in mice
K Song, BH Herzog, J Fu, M Sheng, K Bergstrom, JM McDaniel, Y Kondo, ...
Journal of Biological Chemistry 290 (33), 20159-20166, 2015
332015
Epsin family of endocytic adaptor proteins as oncogenic regulators of cancer progression
KL Tessneer, X Cai, S Pasula, Y Dong, X Liu, B Chang, J McManus, ...
Journal of cancer research updates 2 (3), 144, 2013
312013
Glycogen synthase kinases‐3β controls differentiation of malignant glioma cells
Y Li, H Lu, Y Huang, R Xiao, X Cai, S He, G Yan
International journal of cancer 127 (6), 1271-1282, 2010
302010
DOK3 modulates bone remodeling by negatively regulating osteoclastogenesis and positively regulating osteoblastogenesis
X Cai, J Xing, CL Long, Q Peng, MB Humphrey
Journal of Bone and Mineral Research 32 (11), 2207-2218, 2017
292017
Inorganic polyphosphate amplifies high mobility group box 1–mediated von Willebrand factor release and platelet string formation on endothelial cells
I Biswas, SR Panicker, X Cai, P Mehta-D’souza, AR Rezaie
Arteriosclerosis, Thrombosis, and Vascular Biology 38 (8), 1868-1877, 2018
262018
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
K Song, X Cai, Y Dong, H Wu, Y Wei, U Shankavaram, K Cui, Y Lee, Z Bo, ...
J Clin Invest. 2020 Sep 22;129374. doi: 10.1172/JCI129374. Online ahead of …, 2020
222020
Endocytic adaptor protein epsin is elevated in prostate cancer and required for cancer progression
KL Tessneer, S Pasula, X Cai, Y Dong, X Liu, L Yu, S Hahn, J McManus, ...
International Scholarly Research Notices 2013, 2013
222013
Activated protein C inhibits lipopolysaccharide‐mediated acetylation and secretion of high‐mobility group box 1 in endothelial cells
X Cai, I Biswas, SR Panicker, H Giri, AR Rezaie
Journal of Thrombosis and Haemostasis 17 (5), 803-817, 2019
202019
Thrombomodulin regulation of mitogen-activated protein kinases
H Giri, X Cai, SR Panicker, I Biswas, AR Rezaie
International journal of molecular sciences 20 (8), 1851, 2019
152019
Recombinant fibrinogenase from Agkistrodon acutus venom protects against sepsis via direct degradation of fibrin and TNF-α
R Wang, P Qiu, W Jiang, X Cai, Y Ou, X Su, J Cai, J Chen, W Yin, G Yan
biochemical pharmacology 76 (5), 620-630, 2008
152008
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