CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 1957 | 2014 |
Optical control of mammalian endogenous transcription and epigenetic states S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ... Nature 500 (7463), 472-476, 2013 | 1061 | 2013 |
Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 915 | 2017 |
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9 L Swiech, M Heidenreich, A Banerjee, N Habib, Y Li, J Trombetta, M Sur, ... Nature biotechnology 33 (1), 102-106, 2015 | 884 | 2015 |
Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons N Habib, Y Li, M Heidenreich, L Swiech, I Avraham-Davidi, JJ Trombetta, ... Science 353 (6302), 925-928, 2016 | 540 | 2016 |
Applications of CRISPR–Cas systems in neuroscience M Heidenreich, F Zhang Nature Reviews Neuroscience 17 (1), 36-44, 2016 | 329 | 2016 |
The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus AV Tzingounis, M Heidenreich, T Kharkovets, G Spitzmaul, HS Jensen, ... Proceedings of the National Academy of Sciences 107 (22), 10232-10237, 2010 | 143 | 2010 |
Stretch–Activation of Angiotensin II Type 1a Receptors Contributes to the Myogenic Response of Mouse Mesenteric and Renal Arteries J Schleifenbaum, M Kassmann, IA Szijártó, HC Hercule, JY Tano, ... Circulation research 115 (2), 263-272, 2014 | 139 | 2014 |
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components F Zhang, L Cong, RAN Fei, M Heidenreich, L Swiech US Patent 10,946,108, 2021 | 124 | 2021 |
KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man M Heidenreich, SG Lechner, V Vardanyan, C Wetzel, CW Cremers, ... Nature neuroscience 15 (1), 138-145, 2012 | 123 | 2012 |
Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells F Zhang, M Heidenreich, L Swiech US Patent App. 14/971,169, 2016 | 105 | 2016 |
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons H Tekin, S Simmons, B Cummings, L Gao, X Adiconis, CC Hession, ... Nature Biomedical Engineering 2 (7), 540-554, 2018 | 90 | 2018 |
Methods for determining spatial and temporal gene expression dynamics in single cells A Regev, F Zhang, N Habib, Y Li, M Heidenreich, L Swiech, B Anindita, ... US Patent App. 16/087,036, 2019 | 89 | 2019 |
KCNQ5 K+ channels control hippocampal synaptic inhibition and fast network oscillations P Fidzinski, T Korotkova, M Heidenreich, N Maier, S Schuetze, O Kobler, ... Nature communications 6 (1), 6254, 2015 | 65 | 2015 |
Postsynaptic and differential localization to neuronal subtypes of protocadherin β16 in the mammalian central nervous system D Junghans, M Heidenreich, I Hack, V Taylor, M Frotscher, R Kemler European Journal of Neuroscience 27 (3), 559-571, 2008 | 60 | 2008 |
Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models G Spitzmaul, L Tolosa, BHJ Winkelman, M Heidenreich, MA Frens, ... Journal of Biological Chemistry 288 (13), 9334-9344, 2013 | 44 | 2013 |
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for genome editing L Cong, DBT Cox, M Heidenreich, RJ Platt, L Swiech, F Zhang US Patent 11,407,985, 2022 | 39 | 2022 |
Erratum: Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature Biotechnology 35 (2), 178-178, 2017 | 20 | 2017 |
Crispr enzymes and systems F Zhang, DA Scott, WX Yan, S Choudhury, M Heidenreich US Patent 11,352,647, 2022 | 14 | 2022 |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using viral components F Zhang, L Cong, RAN Fei, M Heidenreich, L Swiech US Patent App. 17/201,347, 2021 | 10 | 2021 |