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Alfred Zippelius
Alfred Zippelius
Professor of Translational Oncology, Co-Head Medical Oncology
Dirección de correo verificada de usb.ch
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First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
BJ Solomon, T Mok, DW Kim, YL Wu, K Nakagawa, T Mekhail, E Felip, ...
New England Journal of Medicine 371 (23), 2167-2177, 2014
35412014
Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label …
TSK Mok, YL Wu, I Kudaba, DM Kowalski, BC Cho, HZ Turna, G Castro, ...
The Lancet 393 (10183), 1819-1830, 2019
28332019
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade
DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ...
Nature medicine 24 (7), 994-1004, 2018
8732018
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12
CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ...
Immunity 49 (6), 1148-1161. e7, 2018
7582018
RNA-Seq signatures normalized by mRNA abundance allow absolute deconvolution of human immune cell types
G Monaco, B Lee, W Xu, S Mustafah, YY Hwang, C Carré, N Burdin, ...
Cell reports 26 (6), 1627-1640. e7, 2019
6342019
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes
P Romero, A Zippelius, I Kurth, MJ Pittet, C Touvrey, EM Iancu, P Corthesy, ...
The Journal of Immunology 178 (7), 4112-4119, 2007
5072007
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance
A Zippelius, P Batard, V Rubio-Godoy, G Bioley, D Liénard, F Lejeune, ...
Cancer research 64 (8), 2865-2873, 2004
4502004
Selective survival of naturally occurring human CD4+ CD25+ Foxp3+ regulatory T cells cultured with rapamycin
L Strauss, TL Whiteside, A Knights, C Bergmann, A Knuth, A Zippelius
The Journal of Immunology 178 (1), 320-329, 2007
4232007
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors
H Wang, F Franco, YC Tsui, X Xie, MP Trefny, R Zappasodi, SR Mohmood, ...
Nature immunology 21 (3), 298-308, 2020
3852020
Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial
M Pless, R Stupp, HB Ris, RA Stahel, W Weder, S Thierstein, MA Gerard, ...
The Lancet 386 (9998), 1049-1056, 2015
3842015
Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors
DS Thommen, J Schreiner, P Müller, P Herzig, A Roller, A Belousov, ...
Cancer immunology research 3 (12), 1344-1355, 2015
3642015
Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow.
A Zippelius, P Kufer, G Honold, MW Köllermann, R Oberneder, ...
Journal of Clinical Oncology 15 (7), 2701-2708, 1997
3571997
Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma.
heinz laeubli, A Zippelius
338*
The immune system and cancer evasion strategies: therapeutic concepts
S Muenst, H Läubli, SD Soysal, A Zippelius, A Tzankov, S Hoeller
Journal of internal medicine 279 (6), 541-562, 2016
3362016
Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade
P Müller, M Kreuzaler, T Khan, DS Thommen, K Martin, K Glatz, S Savic, ...
Science translational medicine 7 (315), 315ra188-315ra188, 2015
3312015
Association of checkpoint inhibitor–induced toxic effects with shared cancer and tissue antigens in non–small cell lung cancer
F Berner, D Bomze, S Diem, OH Ali, M Fässler, S Ring, R Niederer, ...
JAMA oncology 5 (7), 1043-1047, 2019
3062019
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion
YR Yu, H Imrichova, H Wang, T Chao, Z Xiao, M Gao, M Rincon-Restrepo, ...
Nature immunology 21 (12), 1540-1551, 2020
3012020
Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for …
E Putz, K Witter, S Offner, P Stosiek, A Zippelius, J Johnson, R Zahn, ...
Cancer research 59 (1), 241-248, 1999
2541999
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions
N Rufer, A Zippelius, P Batard, MJ Pittet, I Kurth, P Corthesy, JC Cerottini, ...
Blood 102 (5), 1779-1787, 2003
2302003
Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
MA Stanczak, SS Siddiqui, MP Trefny, DS Thommen, KF Boligan, ...
The Journal of clinical investigation 128 (11), 4912-4923, 2018
2272018
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Artículos 1–20