| CRISPR inversion of CTCF sites alters genome topology and enhancer/promoter function Y Guo, Q Xu, D Canzio, J Shou, J Li, DU Gorkin, I Jung, H Wu, Y Zhai, ... Cell 162 (4), 900-910, 2015 | 997 | 2015 |
| CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice Y Guo, K Monahan, H Wu, J Gertz, KE Varley, W Li, RM Myers, T Maniatis, ... Proceedings of the National Academy of Sciences 109 (51), 21081-21086, 2012 | 281 | 2012 |
| Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation S Cuartero, FD Weiss, G Dharmalingam, Y Guo, E Ing-Simmons, ... Nature immunology 19 (9), 932-941, 2018 | 182 | 2018 |
| Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9 J Li, J Shou, Y Guo, Y Tang, Y Wu, Z Jia, Y Zhai, Z Chen, Q Xu, Q Wu Journal of molecular cell biology 7 (4), 284-298, 2015 | 158 | 2015 |
| Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection Z Jia, J Li, X Ge, Y Wu, Y Guo, Q Wu Genome biology 21, 1-24, 2020 | 66 | 2020 |
| Akt-mTOR signaling is involved in Notch-1-mediated glioma cell survival and proliferation N Zhao, Y Guo, M Zhang, L Lin, Z Zheng Oncology reports 23 (5), 1443-1447, 2010 | 64 | 2010 |
| SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression G Hou, ITW Harley, X Lu, T Zhou, N Xu, C Yao, Y Qin, Y Ouyang, J Ma, ... Nature communications 12 (1), 135, 2021 | 61 | 2021 |
| The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus MM Karimi, YA Guo, X Cui, HA Pallikonda, V Horková, YF Wang, SR Gil, ... Nature Communications 12 (1), 99, 2021 | 37 | 2021 |
| Regulation of the Protocadherin Celsr3 Gene and Its Role in Globus Pallidus Development and Connectivity Z Jia, Y Guo, Y Tang, Q Xu, B Li, Q Wu Molecular and cellular biology 34 (20), 3895-3910, 2014 | 31 | 2014 |
| Chromatin jets define the properties of cohesin-driven in vivo loop extrusion Y Guo, E Al-Jibury, R Garcia-Millan, K Ntagiantas, JWD King, AJ Nash, ... Molecular Cell 82 (20), 3769-3780. e5, 2022 | 29 | 2022 |
| Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction D Djeghloul, B Patel, H Kramer, A Dimond, C Whilding, K Brown, ... Nature Communications 11 (1), 4118, 2020 | 28 | 2020 |
| Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin FD Weiss, L Calderon, YF Wang, R Georgieva, Y Guo, N Cvetesic, M Kaur, ... Nature Communications 12 (1), 2919, 2021 | 22 | 2021 |
| Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery T Zhou, X Zhu, Z Ye, YF Wang, C Yao, N Xu, M Zhou, J Ma, Y Qin, Y Shen, ... Nature communications 13 (1), 1855, 2022 | 19 | 2022 |
| Characterization of a cluster of CTCF-binding sites in a protocadherin regulatory region. YN Zhai, Q Xu, Y Guo, Q Wu Yi Chuan= Hereditas 38 (4), 323-336, 2016 | 18 | 2016 |
| Genetic evidence for asymmetric blocking of higher-order chromatin structure by CTCF/cohesin Y Lu, J Shou, Z Jia, Y Wu, J Li, Y Guo, Q Wu Protein & Cell 10 (12), 914-920, 2019 | 15 | 2019 |
| Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus G Hou, T Zhou, N Xu, Z Yin, X Zhu, Y Zhang, Y Cui, J Ma, Y Tang, ... Arthritis & rheumatology 75 (4), 574-585, 2023 | 8 | 2023 |
| Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation I Ferreirós-Vidal, T Carroll, T Zhang, V Lagani, RN Ramirez, ... PLoS Biology 17 (4), e2006506, 2019 | 8 | 2019 |
| 采用 DNA 片段编辑技术反转 CTCF 结合位点改变基因组拓扑结构和增强子与启动子功能 郭亚， 吴强 遗传 37 (10), 1073-1074, 2015 | 6 | 2015 |
| 3D chromosomal landscape reveals miR-146a dysfunctional enhancer in lupus and establishes a CRISPR-mediated approach to inhibit the IFN pathway. X Zhu, Y Zhang, Z Yin, Z Ye, Y Qin, Z Cheng, Y Shen, J Ma, Y Tang, ... Arthritis & Rheumatology (Hoboken, NJ), 2023 | 1 | 2023 |
| A deep learning method for replicate-based analysis of chromosome conformation contacts using Siamese neural networks E Al-Jibury, JWD King, Y Guo, B Lenhard, AG Fisher, M Merkenschlager, ... Nature Communications 14 (1), 5007, 2023 | 1 | 2023 |
