Ivelin Georgiev
Ivelin Georgiev
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Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01
T Zhou, I Georgiev, X Wu, ZY Yang, K Dai, A Finzi, Y Do Kwon, JF Scheid, ...
Science 329 (5993), 811-817, 2010
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ...
Nature 480 (7377), 336-343, 2011
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing
X Wu, T Zhou, J Zhu, B Zhang, I Georgiev, C Wang, X Chen, NS Longo, ...
Science 333 (6049), 1593-1602, 2011
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ...
Nature 514 (7523), 455-461, 2014
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
F Klein, R Diskin, JF Scheid, C Gaebler, H Mouquet, IS Georgiev, ...
Cell 153 (1), 126-138, 2013
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ...
Nature 515 (7525), 138-142, 2014
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
M Rolland, PT Edlefsen, BB Larsen, S Tovanabutra, E Sanders-Buell, ...
Nature 490 (7420), 417-420, 2012
Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G
GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ...
Cell 165 (4), 813-826, 2016
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ...
Immunity 39 (2), 245-258, 2013
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522-531, 2015
Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera
JO Ngwuta, M Chen, K Modjarrad, MG Joyce, M Kanekiyo, A Kumar, ...
Science translational medicine 7 (309), 309ra162-309ra162, 2015
Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth
J Huang, BH Kang, E Ishida, T Zhou, T Griesman, Z Sheng, F Wu, ...
Immunity 45 (5), 1108-1121, 2016
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ...
Science 352 (6287), 828-833, 2016
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
RS Rudicell, YD Kwon, SY Ko, A Pegu, MK Louder, IS Georgiev, X Wu, ...
Journal of virology 88 (21), 12669-12682, 2014
Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses
MG Joyce, AK Wheatley, PV Thomas, GY Chuang, C Soto, RT Bailer, ...
Cell 166 (3), 609-623, 2016
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ...
Nature medicine 24 (6), 857-867, 2018
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ...
Science 340 (6133), 751-756, 2013
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