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Andrea Degasperi
Andrea Degasperi
Research Associate, Early Cancer Institute and Department of Medical Genetics, University of
Verified email at cam.ac.uk - Homepage
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Cited by
Cited by
Year
A compendium of mutational signatures of environmental agents
JE Kucab, X Zou, S Morganella, M Joel, AS Nanda, E Nagy, C Gomez, ...
Cell 177 (4), 821-836. e16, 2019
5222019
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study
J Staaf, D Glodzik, A Bosch, J Vallon-Christersson, C Reuterswärd, ...
Nature medicine 25 (10), 1526-1533, 2019
2372019
Evaluating strategies to normalise biological replicates of Western blot data
A Degasperi, MR Birtwistle, N Volinsky, J Rauch, W Kolch, ...
PloS one 9 (1), e87293, 2014
2282014
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer
N Chopra, H Tovey, A Pearson, R Cutts, C Toms, P Proszek, M Hubank, ...
Nature communications 11 (1), 2662, 2020
1932020
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
A Degasperi, TD Amarante, J Czarnecki, S Shooter, X Zou, D Glodzik, ...
Nature cancer 1 (2), 249-263, 2020
1912020
Mutational signatures: emerging concepts, caveats and clinical applications
G Koh, A Degasperi, X Zou, S Momen, S Nik-Zainal
Nature reviews cancer 21 (10), 619-637, 2021
1872021
A practical guide for mutational signature analysis in hematological malignancies
F Maura, A Degasperi, F Nadeu, D Leongamornlert, H Davies, L Moore, ...
Nature communications 10 (1), 2969, 2019
1692019
Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches
KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ...
Cell systems 2 (1), 38-48, 2016
1662016
Substitution mutational signatures in whole-genome–sequenced cancers in the UK population
A Degasperi, X Zou, T Dias Amarante, A Martinez-Martinez, GCC Koh, ...
Science 376 (6591), abl9283, 2022
1492022
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage
X Zou, GCC Koh, AS Nanda, A Degasperi, K Urgo, TI Roumeliotis, ...
Nature cancer 2 (6), 643-657, 2021
1082021
Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes
RM Mackenzie, IP Salt, WH Miller, A Logan, HA Ibrahim, A Degasperi, ...
Clinical science 124 (6), 403-411, 2013
792013
Whole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers
K Nones, J Johnson, F Newell, AM Patch, H Thorne, SH Kazakoff, ...
Annals of Oncology 30 (7), 1071-1079, 2019
672019
Performance of objective functions and optimisation procedures for parameter estimation in system biology models
A Degasperi, D Fey, BN Kholodenko
NPJ systems biology and applications 3 (1), 20, 2017
602017
Sensitivity analysis of stochastic models of bistable biochemical reactions
A Degasperi, S Gilmore
International School on Formal Methods for the Design of Computer …, 2008
492008
Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification
B Pellegrino, A Herencia-Ropero, A Llop-Guevara, F Pedretti, ...
Cancer research 82 (8), 1646-1657, 2022
452022
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma
CL Jones, A Degasperi, V Grandi, TD Amarante, TJ Mitchell, S Nik-Zainal, ...
Scientific reports 11 (1), 3962, 2021
442021
Some investigations concerning the CTMC and the ODE model derived from Bio-PEPA
F Ciocchetta, A Degasperi, J Hillston, M Calder
Electronic Notes in Theoretical Computer Science 229 (1), 145-163, 2009
442009
Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment …
S Momen, H Fassihi, HR Davies, C Nikolaou, A Degasperi, CM Stefanato, ...
Molecular Case Studies 5 (5), a004408, 2019
432019
Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network
OE Akman, F Ciocchetta, A Degasperi, ML Guerriero
Computational Methods in Systems Biology: 7th International Conference, CMSB …, 2009
302009
DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networks
LK Nguyen, A Degasperi, P Cotter, BN Kholodenko
Scientific reports 5 (1), 12569, 2015
262015
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