Seguir
Haiyang Yu
Título
Citado por
Citado por
Año
Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death
F Gasset-Rosa, S Lu, H Yu, C Chen, Z Melamed, L Guo, J Shorter, ...
Neuron 102 (2), 339-357. e7, 2019
3592019
Allosteric activation of functionally asymmetric RAF kinase dimers
J Hu, EC Stites, H Yu, EA Germino, HS Meharena, PJS Stork, AP Kornev, ...
Cell 154 (5), 1036-1046, 2013
3032013
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
S Akilesh, H Suleiman, H Yu, MC Stander, P Lavin, R Gbadegesin, ...
The Journal of clinical investigation 121 (10), 4127-4137, 2011
2942011
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
H Yu, S Lu, K Gasior, D Singh, S Vazquez-Sanchez, O Tapia, D Toprani, ...
Science 371 (6529), 2021
2052021
Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF
J Hu, H Yu, AP Kornev, J Zhao, EL Filbert, SS Taylor, AS Shaw
Proceedings of the National Academy of Sciences 108 (15), 6067-6072, 2011
1482011
Rac1 activation in podocytes induces rapid foot process effacement and proteinuria
H Yu, H Suleiman, AHJ Kim, JH Miner, A Dani, AS Shaw, S Akilesh
Molecular and cellular biology 33 (23), 4755-4764, 2013
1432013
PAC, an evolutionarily conserved membrane protein, is a proton-activated chloride channel
J Yang, J Chen, M del Carmen Vitery, J Osei-Owusu, J Chu, H Yu, S Sun, ...
Science 364 (6438), 395-399, 2019
992019
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis
H Yu, M Artomov, S Brähler, MC Stander, G Shamsan, MG Sampson, ...
The Journal of clinical investigation 126 (3), 1067-1078, 2016
692016
Intravital and kidney slice imaging of podocyte membrane dynamics
S Brähler, H Yu, H Suleiman, GM Krishnan, BT Saunders, JB Kopp, ...
Journal of the American Society of Nephrology 27 (11), 3285-3290, 2016
562016
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
S Lu, J Hu, OA Arogundade, A Goginashvili, S Vazquez-Sanchez, ...
Nature cell biology 24 (9), 1378-1393, 2022
532022
Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5
X Sun, X Shi, X Sun, Y Luo, X Wu, C Yao, H Yu, D Li, M Liu, J Zhou
Acta pharmacologica Sinica 32 (12), 1543-1548, 2011
512011
Validating the mitotic kinesin Eg5 as a therapeutic target in pancreatic cancer cells and tumor xenografts using a specific inhibitor
M Liu, H Yu, L Huo, J Liu, M Li, J Zhou
Biochemical pharmacology 76 (2), 169-178, 2008
402008
Membralin deficiency dysregulates astrocytic glutamate homeostasis, leading to ALS-like impairment
LL Jiang, B Zhu, Y Zhao, X Li, T Liu, J Pina-Crespo, L Zhou, W Xu, ...
The Journal of Clinical Investigation 129 (8), 3103-3120, 2019
362019
Small-molecule inhibition of Aurora kinases triggers spindle checkpoint-independent apoptosis in cancer cells
L Sun, D Li, X Dong, H Yu, JT Dong, C Zhang, X Lu, J Zhou
Biochemical pharmacology 75 (5), 1027-1034, 2008
222008
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science 371, eabb4309
H Yu, S Lu, K Gasior, D Singh, S Vazquez-Sanchez, O Tapia, D Toprani, ...
142021
Tuning apoptosis and neuroinflammation: TBK1 restrains RIPK1
H Yu, DW Cleveland
Cell 174 (6), 1339-1341, 2018
142018
Tuning T cell signaling sensitivity alters the behavior of CD4+ T cells during an immune response
AAV Milam, JM Bartleson, DL Donermeyer, S Horvath, V Durai, S Raju, ...
The Journal of Immunology 200 (10), 3429-3437, 2018
122018
Significant decrease of ADP release rate underlies the potent activity of dimethylenastron to inhibit mitotic kinesin Eg5 and cancer cell proliferation
L Sun, X Sun, S Xie, H Yu, D Zhong
Biochemical and biophysical research communications 447 (3), 465-470, 2014
72014
Genetic and cellular studies of the Podocyte in focal segmental Glomerulosclerosis
H Yu
Washington University in St. Louis, 2015
12015
CK1δ/ε kinases regulate TDP-43 phosphorylation and are therapeutic targets for ALS-related TDP-43 hyperphosphorylation
VI Ko, K Ong, DW Cleveland, H Yu, JM Ravits
Neurobiology of Disease, 106516, 2024
2024
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20