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Jing Fan
Jing Fan
Morgridge Institute for Research; University of Wisconsin-Madison
Dirección de correo verificada de morgridge.org
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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ...
Genes & development 25 (5), 460-470, 2011
14282011
Quantitative flux analysis reveals folate-dependent NADPH production
J Fan, J Ye, JJ Kamphorst, T Shlomi, CB Thompson, JD Rabinowitz
Nature 510 (7504), 298-302, 2014
10332014
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
JJ Kamphorst, JR Cross, J Fan, E De Stanchina, R Mathew, EP White, ...
Proceedings of the National Academy of Sciences 110 (22), 8882-8887, 2013
6792013
Gut microbial metabolites as multi-kingdom intermediates
KA Krautkramer, J Fan, F Bäckhed
Nature Reviews Microbiology 19 (2), 77-94, 2021
6392021
Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
J Fan, JJ Kamphorst, R Mathew, MK Chung, E White, T Shlomi, ...
Molecular systems biology 9 (1), 712, 2013
4472013
Serine catabolism regulates mitochondrial redox control during hypoxia
J Ye, J Fan, S Venneti, YW Wan, BR Pawel, J Zhang, LWS Finley, C Lu, ...
Cancer discovery 4 (12), 1406-1417, 2014
4252014
Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation
J Ye, A Mancuso, X Tong, PS Ward, J Fan, JD Rabinowitz, CB Thompson
Proceedings of the National Academy of Sciences 109 (18), 6904-6909, 2012
4002012
Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
JO Park, SA Rubin, YF Xu, D Amador-Noguez, J Fan, T Shlomi, ...
Nature chemical biology 12 (7), 482-489, 2016
3932016
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion
J Zhang, J Fan, S Venneti, JR Cross, T Takagi, B Bhinder, H Djaballah, ...
Molecular cell 56 (2), 205-218, 2014
3912014
Metabolic regulation of histone post-translational modifications
J Fan, KA Krautkramer, JL Feldman, JM Denu
ACS chemical biology 10 (1), 95-108, 2015
3192015
As extracellular glutamine levels decline, asparagine becomes an essential amino acid
NN Pavlova, S Hui, JM Ghergurovich, J Fan, AM Intlekofer, RM White, ...
Cell metabolism 27 (2), 428-438. e5, 2018
2712018
Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate
JJ Kamphorst, MK Chung, J Fan, JD Rabinowitz
Cancer & metabolism 2, 1-8, 2014
2322014
Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate
J Fan, X Teng, L Liu, KR Mattaini, RE Looper, MG Vander Heiden, ...
ACS chemical biology 10 (2), 510-516, 2015
1812015
SIRT3 mediates multi-tissue coupling for metabolic fuel switching
KE Dittenhafer-Reed, AL Richards, J Fan, MJ Smallegan, AF Siahpirani, ...
Cell metabolism 21 (4), 637-646, 2015
1802015
Stoichiometry of Site-specific Lysine Acetylation in an Entire Proteome*♦
J Baeza, JA Dowell, MJ Smallegan, J Fan, D Amador-Noguez, Z Khan, ...
Journal of Biological Chemistry 289 (31), 21326-21338, 2014
1652014
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
K Bray, R Mathew, A Lau, JJ Kamphorst, J Fan, J Chen, HY Chen, ...
PloS one 7 (7), e41831, 2012
1612012
Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in Clostridium acetobutylicum
D Amador-Noguez, XJ Feng, J Fan, N Roquet, H Rabitz, JD Rabinowitz
Journal of bacteriology 192 (17), 4452-4461, 2010
1562010
Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
L Liu, S Shah, J Fan, JO Park, KE Wellen, JD Rabinowitz
Nature chemical biology 12 (5), 345-352, 2016
1272016
Liquid chromatography–high resolution mass spectrometry analysis of fatty acid metabolism
JJ Kamphorst, J Fan, W Lu, E White, JD Rabinowitz
Analytical chemistry 83 (23), 9114-9122, 2011
1182011
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ...
Nature chemical biology 16 (7), 731-739, 2020
1152020
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