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David Calligaris
David Calligaris
Head of Laboratory, ImaBiotech CORP
No hay ninguna dirección de correo electrónico verificada.
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Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery
S Santagata, LS Eberlin, I Norton, D Calligaris, DR Feldman, JL Ide, X Liu, ...
Proceedings of the National Academy of Sciences 111 (30), 11121-11126, 2014
2902014
Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
CF Cho, JM Wolfe, CM Fadzen, D Calligaris, K Hornburg, EA Chiocca, ...
Nature communications 8 (1), 15623, 2017
2552017
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis
D Calligaris, D Caragacianu, X Liu, I Norton, CJ Thompson, ...
Proceedings of the National Academy of Sciences 111 (42), 15184-15189, 2014
2532014
Coordinated splicing of regulatory detained introns within oncogenic transcripts creates an exploitable vulnerability in malignant glioma
CJ Braun, M Stanciu, PL Boutz, JC Patterson, D Calligaris, F Higuchi, ...
Cancer cell 32 (4), 411-426. e11, 2017
2002017
Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal
NE Sounni, J Cimino, S Blacher, I Primac, A Truong, G Mazzucchelli, ...
Cell metabolism 20 (2), 280-294, 2014
1842014
Label-free neurosurgical pathology with stimulated Raman imaging
FK Lu, D Calligaris, OI Olubiyi, I Norton, W Yang, S Santagata, XS Xie, ...
Cancer research 76 (12), 3451-3462, 2016
1472016
Mass spectrometry imaging as a tool for surgical decision‐making
D Calligaris, I Norton, DR Feldman, JL Ide, IF Dunn, LS Eberlin, ...
Journal of Mass Spectrometry 48 (11), 1178-1187, 2013
1112013
The efficacy of the Wee1 inhibitor MK-1775 combined with temozolomide is limited by heterogeneous distribution across the blood–brain barrier in glioblastoma
JL Pokorny, D Calligaris, SK Gupta, DO Iyekegbe Jr, D Mueller, ...
Clinical cancer research 21 (8), 1916-1924, 2015
962015
Microtubule targeting agents: from biophysics to proteomics
D Calligaris, P Verdier-Pinard, F Devred, C Villard, D Braguer, D Lafitte
Cellular and molecular life sciences 67, 1089-1104, 2010
942010
A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas
Y Sun, JA Alberta, C Pilarz, D Calligaris, EJ Chadwick, SH Ramkissoon, ...
Neuro-oncology 19 (6), 774-785, 2017
922017
Efficacy of PARP inhibitor rucaparib in orthotopic glioblastoma xenografts is limited by ineffective drug penetration into the central nervous system
KE Parrish, L Cen, J Murray, D Calligaris, S Kizilbash, RK Mittapalli, ...
Molecular cancer therapeutics 14 (12), 2735-2743, 2015
912015
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation
D Calligaris, DR Feldman, I Norton, O Olubiyi, AN Changelian, ...
Proceedings of the National Academy of Sciences 112 (32), 9978-9983, 2015
872015
Advances in top-down proteomics for disease biomarker discovery
D Calligaris, C Villard, D Lafitte
Journal of proteomics 74 (7), 920-934, 2011
812011
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma
EC Randall, KB Emdal, JK Laramy, M Kim, A Roos, D Calligaris, ...
Nature communications 9 (1), 4904, 2018
742018
Rapid discrimination of pediatric brain tumors by mass spectrometry imaging
AR Clark, D Calligaris, MS Regan, D Pomeranz Krummel, JN Agar, ...
Journal of Neuro-oncology 140, 269-279, 2018
582018
Molecular typing of meningiomas by desorption electrospray ionization mass spectrometry imaging for surgical decision-making
D Calligaris, DR Feldman, I Norton, PK Brastianos, IF Dunn, S Santagata, ...
International journal of mass spectrometry 377, 690-698, 2015
552015
Selected protein monitoring in histological sections by targeted MALDI-FTICR in-source decay imaging
D Calligaris, R Longuespée, D Debois, D Asakawa, A Turtoi, ...
Analytical chemistry 85 (4), 2117-2126, 2013
482013
MALDI in-source decay of high mass protein isoforms: application to α-and β-tubulin variants
D Calligaris, C Villard, L Terras, D Braguer, P Verdier-Pinard, D Lafitte
Analytical chemistry 82 (14), 6176-6184, 2010
472010
First in vivo testing of compounds targeting group 3 medulloblastomas using an implantable microdevice as a new paradigm for drug development
O Jonas, D Calligaris, KR Methuku, MM Poe, JP Francois, F Tranghese, ...
Journal of biomedical nanotechnology 12 (6), 1297-1302, 2016
442016
Ultraviolet laser induced hydrogen transfer reaction: study of the first step of MALDI in-source decay mass spectrometry
D Asakawa, D Calligaris, N Smargiasso, E De Pauw
The Journal of Physical Chemistry B 117 (8), 2321-2327, 2013
432013
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Artículos 1–20