Dagmar Ehrnhoefer

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Niels Henning SkotteAssistant Professor, Department for Drug Design and Pharmacology, UCPHDirección de correo verificada de sund.ku.dk
Amber L SouthwellBurnett School of Biomedical Sciences, University of Central FloridaDirección de correo verificada de ucf.edu
Justin LegleiterWest Virginia UniversityDirección de correo verificada de mail.wvu.edu
Stefanie Butlandhttps://www.openscapes.org/Dirección de correo verificada de cmmt.ubc.ca
Daniel OffenTel Aviv UniversityDirección de correo verificada de post.tau.ac.il
X. WillIam YangProfessor, Dept. Psychiatry & Semel Institute, David Geffen School of Medicine at UCLADirección de correo verificada de mednet.ucla.edu
Jason D GalpinAssociate Research Scientist, University of IowaDirección de correo verificada de uiowa.edu
Barak RotblatBen Gurion University of the NegevDirección de correo verificada de bgu.ac.il
Gerry MelinoUniversity Rome Tor Vergata, Italy & CDDpress, UK.Dirección de correo verificada de uniroma2.it
Roberto NitschAstraZeneca R&DDirección de correo verificada de astrazeneca.com
Josef PenningerLife Sciences Institute, University of British Columbia / IMBA Institut für MolekulareDirección de correo verificada de imba.oeaw.ac.at
Gabriel LeprivierUniversity Hospital Düsseldorf, HHUDirección de correo verificada de med.uni-duesseldorf.de
Syam SomasekharanAssistant Professor, University of British ColumbiaDirección de correo verificada de mail.ubc.ca
Guy SalvesenProfessor, Sanford-Burnham Medical Research InstituteDirección de correo verificada de sbpdiscovery.org
Jeff CarrollAssociate Professor, Department of Neurology, University of WashingtonDirección de correo verificada de uw.edu
Jason LerchWellcome Centre for Integrative Neuroimaging, University of OxfordDirección de correo verificada de ndcn.ox.ac.uk
Mark HenkelmanSickkidsDirección de correo verificada de sickkids.ca
Annalisa PastoreESRF

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Dagmar Ehrnhoefer

Principal Research Scientist, AbbVie GmbH Co KG, Germany

Dirección de correo verificada de abbvie.com

Neurodegeneration Alzheimer's disease Huntington disease post-translational modifications


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers DE Ehrnhoefer, J Bieschke, A Boeddrich, M Herbst, L Masino, R Lurz, ... Nature structural & molecular biology 15 (6), 558-566, 2008	1563	2008
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity J Bieschke, J Russ, RP Friedrich, DE Ehrnhoefer, H Wobst, ... Proceedings of the National Academy of Sciences 107 (17), 7710-7715, 2010	1077	2010
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin S Okamoto, MA Pouladi, M Talantova, D Yao, P Xia, DE Ehrnhoefer, ... Nature medicine 15 (12), 1407-1413, 2009	483	2009
Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models DE Ehrnhoefer, M Duennwald, P Markovic, JL Wacker, S Engemann, ... Human molecular genetics 15 (18), 2743-2751, 2006	464	2006
Autophagy in Huntington disease and huntingtin in autophagy DDO Martin, S Ladha, DE Ehrnhoefer, MR Hayden Trends in neurosciences 38 (1), 26-35, 2015	361	2015
Small changes, big impact: posttranslational modifications and function of huntingtin in Huntington disease DE Ehrnhoefer, L Sutton, MR Hayden The Neuroscientist 17 (5), 475-492, 2011	207	2011
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin MA Pouladi, RK Graham, JM Karasinska, Y Xie, RD Santos, Å Petersén, ... Brain 132 (4), 919-932, 2009	180	2009
Caspase-6 and neurodegeneration RK Graham, DE Ehrnhoefer, MR Hayden Trends in neurosciences 34 (12), 646-656, 2011	141	2011
Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression MA Pouladi, Y Xie, NH Skotte, DE Ehrnhoefer, RK Graham, JE Kim, ... Human molecular genetics 19 (8), 1528-1538, 2010	139	2010
Mouse models of Huntington disease: variations on a theme DE Ehrnhoefer, SL Butland, MA Pouladi, MR Hayden Disease models & mechanisms 2 (3-4), 123-129, 2009	129	2009
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ... Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014	104	2014
Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development DE Ehrnhoefer, BKY Wong, MR Hayden Nature reviews Drug discovery 10 (11), 853-867, 2011	86	2011
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice V Uribe, BKY Wong, RK Graham, CL Cusack, NH Skotte, MA Pouladi, ... Human molecular genetics 21 (9), 1954-1967, 2012	75	2012
A validated antibody panel for the characterization of tau post-translational modifications E Ercan, S Eid, C Weber, A Kowalski, M Bichmann, A Behrendt, F Matthes, ... Molecular neurodegeneration 12, 1-19, 2017	74	2017
A Huntingtin-based peptide inhibitor of caspase-6 provides protection from mutant Huntingtin-induced motor and behavioral deficits I Aharony, DE Ehrnhoefer, A Shruster, X Qiu, S Franciosi, MR Hayden, ... Human molecular genetics 24 (9), 2604-2614, 2015	66	2015
A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain E Ercan-Herbst, J Ehrig, DC Schöndorf, A Behrendt, B Klaus, ... Acta neuropathologica communications 7, 1-19, 2019	62	2019
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice BKY Wong, DE Ehrnhoefer, RK Graham, DDO Martin, S Ladha, V Uribe, ... Neurobiology of disease 76, 24-36, 2015	62	2015
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin DE Ehrnhoefer, NH Skotte, S Ladha, YTN Nguyen, X Qiu, Y Deng, ... Human molecular genetics 23 (3), 717-729, 2014	58	2014
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease DE Ehrnhoefer, DDO Martin, ME Schmidt, X Qiu, S Ladha, NS Caron, ... Acta neuropathologica communications 6, 1-16, 2018	56	2018
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease MA Pouladi, E Brillaud, Y Xie, P Conforti, RK Graham, DE Ehrnhoefer, ... Neurobiology of disease 48 (3), 282-289, 2012	53	2012

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