Trevor Biden
Trevor Biden
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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
DR Laybutt, AM Preston, MC Åkerfeldt, JG Kench, AK Busch, AV Biankin, ...
Diabetologia 50 (4), 752-763, 2007
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
C Schmitz-Peiffer, DL Craig, TJ Biden
Journal of Biological Chemistry 274 (34), 24202-24210, 1999
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1, 4, 5-trisphosphate
M Prentki, TJ Biden, D Janjic, RF Irvine, MJ Berridge, CB Wollheim
Nature 309 (5968), 562-564, 1984
Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells.
LA Selbie, C Schmitz-Peiffer, Y Sheng, TJ Biden
Journal of Biological Chemistry 268 (32), 24296-24302, 1993
Alterations in the expression and cellular localization of protein kinase C isozymes ε and θ are associated with insulin resistance in skeletal muscle of the high-fat–fed rat
C Schmitz-Peiffer, CL Browne, ND Oakes, A Watkinson, DJ Chisholm, ...
Diabetes 46 (2), 169-178, 1997
Protein kinase Cζ activation mediates glucagon-like peptide-1–induced pancreatic β-cell proliferation
J Buteau, S Foisy, CJ Rhodes, L Carpenter, TJ Biden, M Prentki
Diabetes 50 (10), 2237-2243, 2001
Guanine nucleotides induce Ca2+-independent insulin secretion from permeabilized RINm5F cells.
L Vallar, TJ Biden, CB Wollheim
Journal of Biological Chemistry 262 (11), 5049-5056, 1987
Structural subtypes of the dopamine D2 receptor are functionally distinct: expression of the cloned D2A and D2B subtypes in a heterologous cell line.
G Hayes, TJ Biden, LA Selbie, J Shine
Molecular Endocrinology 6 (6), 920-926, 1992
Inositol 1,4,5-trisphosphate mobilizes intracellular Ca2+ from permeabilized insulin-secreting cells
TJ Biden, M Prentki, RF Irvine, MJ Berridge, CB Wollheim
Biochemical Journal 223 (2), 467-473, 1984
Ca2+ regulates the inositol tris/tetrakisphosphate pathway in intact and broken preparations of insulin-secreting RINm5F cells.
TJ Biden, CB Wollheim
Journal of Biological Chemistry 261 (26), 11931-11934, 1986
Expression profiling of palmitate-and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic β-cell function
AK Busch, D Cordery, GS Denyer, TJ Biden
Diabetes 51 (4), 977-987, 2002
Lipotoxic endoplasmic reticulum stress, β cell failure, and type 2 diabetes mellitus
TJ Biden, E Boslem, KY Chu, N Sue
Trends in Endocrinology & Metabolism 25 (8), 389-398, 2014
Ca2+-mediated generation of inositol 1, 4, 5-triphosphate and inositol 1, 3, 4, 5-tetrakisphosphate in pancreatic islets. Studies with K+, glucose, and carbamylcholine.
TJ Biden, B Peter-Riesch, W Schlegel, CB Wollheim
Journal of Biological Chemistry 262 (8), 3567-3571, 1987
Second messenger function of inositol 1, 4, 5-trisphosphate. Early changes in inositol phosphates, cytosolic Ca2+, and insulin release in carbamylcholine-stimulated RINm5F cells.
CB Wollheim, TJ Biden
Journal of Biological Chemistry 261 (18), 8314-8319, 1986
Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic β-cells from lipoapoptosis
AK Busch, E Gurisik, DV Cordery, M Sudlow, GS Denyer, DR Laybutt, ...
Diabetes 54 (10), 2917-2924, 2005
A role for protein phosphatase 2A–like activity, but not atypical protein kinase Cζ, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate
R Cazzolli, L Carpenter, TJ Biden, C Schmitz-Peiffer
Diabetes 50 (10), 2210-2218, 2001
A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking
E Boslem, G MacIntosh, AM Preston, C Bartley, AK Busch, M Fuller, ...
Biochemical Journal 435 (1), 267-276, 2011
Protein kinase C function in muscle, liver, and β-cells and its therapeutic implications for type 2 diabetes
C Schmitz-Peiffer, TJ Biden
Diabetes 57 (7), 1774-1783, 2008
PKCδ is required for mitochondrial-dependent apoptosis in salivary epithelial cells
AA Matassa, L Carpenter, TJ Biden, MJ Humphries, ME Reyland
Journal of Biological Chemistry 276 (32), 29719-29728, 2001
G protein-coupled receptor (GPR) 40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1
M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, ...
Diabetologia 55 (10), 2682-2692, 2012
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