| AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis RW Wilkinson, R Odedra, SP Heaton, SR Wedge, NJ Keen, C Crafter, ... Clinical cancer research 13 (12), 3682-3688, 2007 | 410 | 2007 |
| Discovery, Synthesis, and in Vivo Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase AA Mortlock, KM Foote, NM Heron, FH Jung, G Pasquet, JJM Lohmann, ... Journal of medicinal chemistry 50 (9), 2213-2224, 2007 | 315 | 2007 |
| Grignard reagents: new developments HG Richey (No Title), 2000 | 295 | 2000 |
| Catalytic and enantioselective route to medium-ring heterocycles. Asymmetric zirconium-catalyzed ethylmagnesation of seven-and eight-membered rings MS Visser, NM Heron, MT Didiuk, JF Sagal, AH Hoveyda Journal of the American Chemical Society 118 (18), 4291-4298, 1996 | 158 | 1996 |
| SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors NM Heron, M Anderson, DP Blowers, J Breed, JM Eden, S Green, GB Hill, ... Bioorganic & medicinal chemistry letters 16 (5), 1320-1323, 2006 | 150 | 2006 |
| Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors FH Jung, G Pasquet, C Lambert-van der Brempt, JJM Lohmann, N Warin, ... Journal of medicinal chemistry 49 (3), 955-970, 2006 | 119 | 2006 |
| Progress in the development of selective inhibitors of aurora kinases AA Mortlock, NJ Keen, FH Jung, NM Heron, RW Wilkinson, S Green Current topics in medicinal chemistry 5 (8), 807-821, 2005 | 119 | 2005 |
| Ni-catalyzed asymmetric addition of Grignard reagents to unsaturated cyclic acetals. The influence of added phosphine on enantioselectivity E Gomez-Bengoa, NM Heron, MT Didiuk, CA Luchaco, AH Hoveyda Journal of the American Chemical Society 120 (30), 7649-7650, 1998 | 97 | 1998 |
| Discovery of an orally bioavailable NK1 receptor antagonist,(2S, 3S)-(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl) amine (GR203040), with potent antiemetic activity P Ward, DR Armour, DE Bays, B Evans, GMP Giblin, N Heron, T Hubbard, ... Journal of medicinal chemistry 38 (26), 4985-4992, 1995 | 73 | 1995 |
| Stereoselective heteroatom-assisted allylic alkylation of cyclic ethers with Grignard reagents. A convenient route to enantiomerically pure carbocycles NM Heron, JA Adams, AH Hoveyda Journal of the American Chemical Society 119 (26), 6205-6206, 1997 | 60 | 1997 |
| Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: Selective inhibitors of Aurora B kinase with potent anti-tumor activity KM Foote, AA Mortlock, NM Heron, FH Jung, GB Hill, G Pasquet, ... Bioorganic & medicinal chemistry letters 18 (6), 1904-1909, 2008 | 52 | 2008 |
| Phosphonooxy quinazoline derivatives and their pharmaceutical use NM Heron, AA Mortlock US Patent 7,528,121, 2009 | 45 | 2009 |
| (1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly … AG Dossetter, H Beeley, J Bowyer, CR Cook, JJ Crawford, JE Finlayson, ... Journal of medicinal chemistry 55 (14), 6363-6374, 2012 | 37 | 2012 |
| Head-Up; An interdisciplinary, participatory and co-design process informing the development of a novel head and neck support for people living with progressive neck muscle … H Reed, J Langley, A Stanton, N Heron, Z Clarke, S Judge, A McCarthy, ... Journal of medical engineering & technology 39 (7), 404-410, 2015 | 36 | 2015 |
| Comprehensive Asymmetric Catalysis AN Hoveyda, NV Heron, EN Jacobsen, A Pfaltz, H Yamamoto) Springer Verlag, Berlin, 1999 | 35 | 1999 |
| Evaluating a novel cervical orthosis, the Sheffield Support Snood, in patients with amyotrophic lateral sclerosis/motor neuron disease with neck weakness S Baxter, H Reed, Z Clarke, S Judge, N Heron, A Mccarthy, J Langley, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 17 (5-6), 436-442, 2016 | 33 | 2016 |
| On the use of the modified Julia olefination for bryostatin synthesis JV Allen, AP Green, S Hardy, NM Heron, ATL Lee, EJ Thomas Tetrahedron Letters 49 (44), 6352-6355, 2008 | 32 | 2008 |
| Assessment of the Sheffield Support Snood, an innovative cervical orthosis designed for people affected by neck muscle weakness S Pancani, J Rowson, W Tindale, N Heron, J Langley, AD McCarthy, ... Clinical biomechanics 32, 201-206, 2016 | 29 | 2016 |
| Development of two electronic bladder diaries: a patient and healthcare professionals pilot study A Mangera, A Marzo, N Heron, D Fernando, K Hameed, AHA Soliman, ... Neurourology and Urodynamics 33 (7), 1101-1109, 2014 | 29 | 2014 |
| Stereoselective chelate-controlled addition of Grignard reagents to unsaturated medium-ring heterocycles JA Adams, NM Heron, AM Koss, AH Hoveyda The Journal of Organic Chemistry 64 (3), 854-860, 1999 | 26 | 1999 |
Joseph LangleySheffield Hallam UniversityDirección de correo verificada de shu.ac.uk
